Cognitive and psychopathology correlates of brain white/grey matter structure in severely psychotic schizophrenic inpatients
Publication date: June 2018Source: Schizophrenia Research: Cognition, Volume 12Author(s): Nerisa Banaj, Federica Piras, Fabrizio Piras, Valentina Ciullo, Mariangela Iorio, Claudia Battaglia, Donatella Pantoli, Giuseppe Ducci, Gianfranco SpallettaAbstractThe brain structural correlates of cognitive and psychopathological symptoms within the active phase in severely psychotic schizophrenic inpatients have been rarely investigated. Twenty-eight inpatients with a DSM-5 diagnosis of Schizophrenia (SZ), admitted for acute psychotic decompensation, were assessed through a comprehensive neuropsychological and psychopathological ba...
Source: Schizophrenia Research: Cognition - July 5, 2018 Category: Psychiatry Source Type: research
Speech-on-speech masking and psychotic symptoms in schizophrenia
This study investigated whether the TSR impairment in schizophrenia is associated with their impaired auditory working memory or certain psychotic symptoms. Thirty participants with schizophrenia (mean age = 35.2 ± 12.7 years) and 30 demographics-matched healthy controls (mean age = 32.9 ± 10.9 years) were tested for their TSR against a two-talker-speech masker. Auditory working memory and memory capacity were evaluated using the Paced Auditory Serial Addition Test (PASAT) and Digit Span Test. Psychotic symptoms were evaluated using the Positive and Negative Syndrome Scale (PANSS). The results showed ...
Source: Schizophrenia Research: Cognition - July 5, 2018 Category: Psychiatry Source Type: research
Long-term treatment with clozapine and verbal memory performance in schizophrenia
Publication date: June 2018Source: Schizophrenia Research: Cognition, Volume 12Author(s): Letícia S. Czepielewski, Marina D.B. Londero, Mathias H. de Sousa, Carolina P. Perin, Helena C. Maldonado, Felipe C.A. Claudino, Clarissa S. GamaAbstractClozapine is more efficacious than first-generation antipsychotics for positive and negative symptoms, although it is related with serious adverse effects. Because of this profile, it could also have an impact on cognition. Therefore, we evaluated learning ability of 31 treatment-resistant individuals with SZ using clozapine uninterruptedly for 18.23 ± 4.71 years and 26 non-tr...
Source: Schizophrenia Research: Cognition - July 5, 2018 Category: Psychiatry Source Type: research
Predictive timing disturbance is a precise marker of schizophrenia
Publication date: June 2018Source: Schizophrenia Research: Cognition, Volume 12Author(s): Valentina Ciullo, Federica Piras, Daniela Vecchio, Nerisa Banaj, Jennifer T. Coull, Gianfranco SpallettaAbstractTiming disturbances have being proposed as a key component of schizophrenia pathogenesis. However, the contribution of cognitive impairment to such disorders has not been clarified. Here, we investigated duration estimation and predictive timing in 30 patients with DSM-5 diagnosis of schizophrenia (SZ) compared to 30 healthy controls (HC). Duration estimation was examined in a temporal and colour discrimination task, fully c...
Source: Schizophrenia Research: Cognition - July 5, 2018 Category: Psychiatry Source Type: research
Effect of cognitive function on jumping to conclusion in patients with schizophrenia
Publication date: June 2018Source: Schizophrenia Research: Cognition, Volume 12Author(s): Tomoya Takeda, Masahito Nakataki, Masashi Ohta, Sayo Hamatani, Kanae Matsuura, Tetsuro OhmoriAbstractThe “jumping to conclusion” (JTC) bias is related to the formation and maintenance of delusions. Higher JTC bias can be based on both neurocognitive dysfunction and social cognitive dysfunction in patients with schizophrenia. The aim of this study was to assess the relationship between JTC bias, neurocognition, and social cognition in patients with schizophrenia.A total of 22 patients with schizophrenia and 21 controls participated...
Source: Schizophrenia Research: Cognition - July 5, 2018 Category: Psychiatry Source Type: research
The relationship between clinical insight and cognitive and affective empathy in schizophrenia
ConclusionFindings suggest that affective empathy is relatively intact across phases of illness whereas cognitive empathy abilities are compromised and could be targets for psychotherapy intervention. (Source: Schizophrenia Research: Cognition)
Source: Schizophrenia Research: Cognition - July 5, 2018 Category: Psychiatry Source Type: research
The impact of reward on attention in schizophrenia
Publication date: June 2018Source: Schizophrenia Research: Cognition, Volume 12Author(s): Sonia Bansal, Benjamin M. Robinson, Joy J. Geng, Carly J. Leonard, Britta Hahn, Steven J. Luck, James M. GoldAbstractTraditionally, attention was thought to be directed by either top-down goals or bottom-up salience. Recent studies have shown that the reward history of a stimulus feature also acts as a powerful attentional cue. This is particularly relevant in schizophrenia, which is characterized by motivational and attentional deficits. Here, we examine the impact of reward on selective attention.Forty-eight people with schizophreni...
Source: Schizophrenia Research: Cognition - July 5, 2018 Category: Psychiatry Source Type: research
Increased social cognitive bias in subclinical paranoia
Publication date: June 2018Source: Schizophrenia Research: Cognition, Volume 12Author(s): Hans S. Klein, Skylar Kelsven, Amy E. Pinkham (Source: Schizophrenia Research: Cognition)
Source: Schizophrenia Research: Cognition - July 5, 2018 Category: Psychiatry Source Type: research
Increased social cognitive bias in subclinical paranoia
Publication date: June 2018 Source:Schizophrenia Research: Cognition, Volume 12 Author(s): Hans S. Klein, Skylar Kelsven, Amy E. Pinkham (Source: Schizophrenia Research: Cognition)
Source: Schizophrenia Research: Cognition - May 30, 2018 Category: Psychiatry Source Type: research
The impact of reward on attention in schizophrenia
Publication date: June 2018 Source:Schizophrenia Research: Cognition, Volume 12 Author(s): Sonia Bansal, Benjamin M. Robinson, Joy J. Geng, Carly J. Leonard, Britta Hahn, Steven J. Luck, James M. Gold Traditionally, attention was thought to be directed by either top-down goals or bottom-up salience. Recent studies have shown that the reward history of a stimulus feature also acts as a powerful attentional cue. This is particularly relevant in schizophrenia, which is characterized by motivational and attentional deficits. Here, we examine the impact of reward on selective attention. Forty-eight people with schizoph...
Source: Schizophrenia Research: Cognition - May 30, 2018 Category: Psychiatry Source Type: research
The relationship between clinical insight and cognitive and affective empathy in schizophrenia
Conclusion Findings suggest that affective empathy is relatively intact across phases of illness whereas cognitive empathy abilities are compromised and could be targets for psychotherapy intervention. (Source: Schizophrenia Research: Cognition)
Source: Schizophrenia Research: Cognition - May 16, 2018 Category: Psychiatry Source Type: research
Effect of cognitive function on jumping to conclusion in patients with schizophrenia
Publication date: June 2018 Source:Schizophrenia Research: Cognition, Volume 12 Author(s): Tomoya Takeda, Masahito Nakataki, Masashi Ohta, Sayo Hamatani, Kanae Matsuura, Tetsuro Ohmori The “jumping to conclusion” (JTC) bias is related to the formation and maintenance of delusions. Higher JTC bias can be based on both neurocognitive dysfunction and social cognitive dysfunction in patients with schizophrenia. The aim of this study was to assess the relationship between JTC bias, neurocognition, and social cognition in patients with schizophrenia. A total of 22 patients with schizophrenia and 21 controls participa...
Source: Schizophrenia Research: Cognition - May 16, 2018 Category: Psychiatry Source Type: research
Predictive timing disturbance is a precise marker of schizophrenia
Publication date: June 2018 Source:Schizophrenia Research: Cognition, Volume 12 Author(s): Valentina Ciullo, Federica Piras, Daniela Vecchio, Nerisa Banaj, Jennifer T. Coull, Gianfranco Spalletta Timing disturbances have being proposed as a key component of schizophrenia pathogenesis. However, the contribution of cognitive impairment to such disorders has not been clarified. Here, we investigated duration estimation and predictive timing in 30 patients with DSM-5 diagnosis of schizophrenia (SZ) compared to 30 healthy controls (HC). Duration estimation was examined in a temporal and colour discrimination task, fully...
Source: Schizophrenia Research: Cognition - May 16, 2018 Category: Psychiatry Source Type: research
Long-term treatment with clozapine and verbal memory performance in schizophrenia
Publication date: June 2018 Source:Schizophrenia Research: Cognition, Volume 12 Author(s): Letícia S. Czepielewski, Marina D.B. Londero, Mathias H. de Sousa, Carolina P. Perin, Helena C. Maldonado, Felipe C.A. Claudino, Clarissa S. Gama Clozapine is more efficacious than first-generation antipsychotics for positive and negative symptoms, although it is related with serious adverse effects. Because of this profile, it could also have an impact on cognition. Therefore, we evaluated learning ability of 31 treatment-resistant individuals with SZ using clozapine uninterruptedly for 18.23 ± 4.71 years and 26 non...
Source: Schizophrenia Research: Cognition - March 9, 2018 Category: Psychiatry Source Type: research
Speech-on-speech masking and psychotic symptoms in schizophrenia
This study investigated whether the TSR impairment in schizophrenia is associated with their impaired auditory working memory or certain psychotic symptoms. Thirty participants with schizophrenia (mean age = 35.2 ± 12.7 years) and 30 demographics-matched healthy controls (mean age = 32.9 ± 10.9 years) were tested for their TSR against a two-talker-speech masker. Auditory working memory and memory capacity were evaluated using the Paced Auditory Serial Addition Test (PASAT) and Digit Span Test. Psychotic symptoms were evaluated using the Positive and Negative Syndrome Scale (PANSS). The results showed ...
Source: Schizophrenia Research: Cognition - March 6, 2018 Category: Psychiatry Source Type: research
