Meeting overview: Sensory perception and schizophrenia, Lausanne, Switzerland June 31 –July 1, 2014
This article summarizes a conference on visual processing dysfunction in schizophrenia held in Lausanne, Switzerland from June 30 to July 1, 2014 and introduces this special issue. Speakers focused on multiple aspects of visual dysfunction in schizophrenia using behavioral, neurophysiological and fMRI-based approaches. Four main themes emerged. First was a focus on response disturbances within the early visual system, using paradigms such as sensory EEG and MEG-based responses. Second, behavioral deficits were noted in processing related to local interaction within visual regions, using paradigms such as Vernier acuity or ...
Source: Schizophrenia Research: Cognition - June 17, 2016 Category: Psychiatry Source Type: research

Recuperaci ón Clinica Pero No Cognitiva En Esquizofrenia A Traves De La Experiencia Del Cine De Ficcion
Publication date: December 2015 Source:Schizophrenia Research: Cognition, Volume 2, Issue 4 Author(s): J. Peña, P. Sánchez, E. Elizagárate, N. Ibarretxe-Bilbao, J. Ezcurra, L. Caballero, M. Margariños, I. García Del Castillo, M. Gutiérrez, N. Ojeda Introducción Una de las críticas que se hace a las técnicas de la rehabilitación es la limitada generalización a la vida cotidiana del paciente. El cine se ha empleado como herramienta de rehabilitación psiquiátrica en el pasado con el objetivo principal de facilitar el entrenamiento en habilidades sociales y de comunicación. En este estudio...
Source: Schizophrenia Research: Cognition - June 17, 2016 Category: Psychiatry Source Type: research

El procesamiento temporal en la esquizofrenia: Revisi ón
Publication date: December 2015 Source:Schizophrenia Research: Cognition, Volume 2, Issue 4 Author(s): Irene Alústiza, Nuria Pujol, Patricio Molero, Felipe Ortuño We review the main contributions of the cognitive neuroscience literature in the field of time processing in schizophrenia. First, we summarize the theoretical concepts and terminology related to time and time estimation as well as the characterization of this deficit in the illness. Secondly, we deeply review the neuroanatomical basis of this deficit and its interaction with other cognitive processes and clinical symptoms. Thirdly, we specifically ...
Source: Schizophrenia Research: Cognition - June 17, 2016 Category: Psychiatry Source Type: research

B úsqueda De Nuevos Biomarcadores De La Cognición En Esquizofrenia
Publication date: December 2015 Source:Schizophrenia Research: Cognition, Volume 2, Issue 4 Author(s): Rafael Penadés, Clemente Garcia-Rizo, Miquel Bioque, Alexandre González-Rodríguez, Bibiana Cabrera, Gisela Mezquida, Miquel Bernardo La búsqueda de biomarcadores en la cognición ha centrado una gran parte de las investigaciones en pacientes con esquizofrenia. La literatura científica es heterogénea y son escasos los estudios disponibles que permitan establecer un modelo integrador de la etiopatogenia y respuesta terapéutica basada en estos marcadores. En el presente trabajo nos proponemos revisar...
Source: Schizophrenia Research: Cognition - June 17, 2016 Category: Psychiatry Source Type: research

e-Motional Training ®: Pilot study on a novel online training program on social cognition for patients with schizophrenia
Conclusion ET® enables self-training in SC and online follow-up by the therapist, thereby covering the lack of online intervention instruments validated for patients with SC deficits. Our preliminary results demonstrate the feasibility of ET® and its possible efficacy in improving emotion recognition, ToM and AS. (Source: Schizophrenia Research: Cognition)
Source: Schizophrenia Research: Cognition - June 17, 2016 Category: Psychiatry Source Type: research

Change in daytime sleepiness and cognitive function in a 6-month, double-blind study of lurasidone and quetiapine XR in patients with schizophrenia
The objective of this post-hoc analysis was to evaluate the long-term effects of lurasidone and quetiapine XR on daytime sleepiness and neurocognitive performance during a 6-month, double-blind continuation study, in subjects who completed an initial 6-week, randomized, placebo-controlled trial comparing these agents. Daytime sleepiness, cognitive performance, and health-related quality of life were assessed with the Epworth Sleepiness Scale (ESS), CogState computerized battery, and the Quality of Well-Being (QWB-SA) Scale, respectively. Treatment with flexible-dose lurasidone 40–160mg/d, administered once daily in the e...
Source: Schizophrenia Research: Cognition - June 2, 2016 Category: Psychiatry Source Type: research

Schizotypy and mindfulness: Magical thinking without suspiciousness characterizes mindfulness meditators
Publication date: September 2016 Source:Schizophrenia Research: Cognition, Volume 5 Author(s): Elena Antonova, Kavitha Amaratunga, Bernice Wright, Ulrich Ettinger, Veena Kumari Despite growing evidence for demonstrated efficacy of mindfulness in various disorders, there is a continuous concern about the relationship between mindfulness practice and psychosis. As schizotypy is part of the psychosis spectrum, we examined the relationship between long-term mindfulness practice and schizotypy in two independent studies. Study 1 included 24 experienced mindfulness practitioners (19 males) from the Buddhist traditi...
Source: Schizophrenia Research: Cognition - June 1, 2016 Category: Psychiatry Source Type: research

Are persistent delusions in schizophrenia associated with aberrant salience?
Conclusion These findings do not support the hypothesis that persistent delusions are related to aberrant motivational salience processing in TRS patients. However, they do support the view that patients with schizophrenia have impaired reward learning. (Source: Schizophrenia Research: Cognition)
Source: Schizophrenia Research: Cognition - May 17, 2016 Category: Psychiatry Source Type: research

Effectiveness of fast mapping to promote learning in schizophrenia
Publication date: June 2016 Source:Schizophrenia Research: Cognition, Volume 4 Author(s): Stephanie A. Korenic, Sarah J. Nisonger, Benjamin W. Krause, S. Andrea Wijtenburg, L. Elliot Hong, Laura M. Rowland Fast mapping (FM), a process that promotes the expeditious incidental learning of information, is thought to support rapid vocabulary acquisition in young children through extra-medial temporal lobe (MTL) regions. A recent study suggested that patients with MTL damage resulting in profound amnesia were able to learn novel word–image associations using an FM paradigm. The present study investigated wheth...
Source: Schizophrenia Research: Cognition - May 16, 2016 Category: Psychiatry Source Type: research

Dissociation mediates the relationship between peer victimization and hallucinatory experiences among early adolescents
We examined whether dissociation mediates the relationship between peer victimization and hallucinatory experiences among 10-year-old adolescents using a population-based cross-sectional survey of early adolescents and their main parent (Tokyo Early Adolescence Survey; N =4478). We examined the mediating effect of dissociation, as well as external locus of control and depressive symptoms, on the relationship between peer victimization and hallucinatory experiences using path analysis. The model assuming mediation effects indicated good model fit (comparative fit index = .999; root mean square error of approximation = .015)...
Source: Schizophrenia Research: Cognition - May 15, 2016 Category: Psychiatry Source Type: research

e-Motional Training®: Pilot study on a novel online training program on social cognition for patients with schizophrenia
Conclusion ET® enables self-training in SC and online follow-up by the therapist, thereby covering the lack of online intervention instruments validated for patients with SC deficits. Our preliminary results demonstrate the feasibility of ET® and its possible efficacy in improving emotion recognition, ToM and AS. (Source: Schizophrenia Research: Cognition)
Source: Schizophrenia Research: Cognition - March 13, 2016 Category: Psychiatry Source Type: research

Kynurenine pathway and cognitive impairments in schizophrenia: Pharmacogenetics of galantamine and memantine
Publication date: June 2016 Source:Schizophrenia Research: Cognition, Volume 4 Author(s): Maju Mathew Koola The Measurement and Treatment Research to Improve Cognition in Schizophrenia (MATRICS) project designed to facilitate the development of new drugs for the treatment of cognitive impairments in people with schizophrenia, identified three drug mechanisms of particular interest: dopaminergic, cholinergic, and glutamatergic. Galantamine is an acetylcholinesterase inhibitor and a positive allosteric modulator of the α7 nicotinic receptors. Memantine is an N-methyl-D-aspartate (NMDA) receptor antagonist. There is ev...
Source: Schizophrenia Research: Cognition - March 13, 2016 Category: Psychiatry Source Type: research

Attribution bias and social anxiety in schizophrenia
The objective of the present study was thus to determine if individuals with schizophrenia and a comorbid social anxiety disorder (SZ+) show distinct attribution biases as compared with individuals with schizophrenia without social anxiety (SZ−) and healthy controls. Attribution biases were assessed with the Internal, Personal, and Situational Attributions Questionnaire in 41 individual with schizophrenia and 41 healthy controls. Results revealed the lack of the normal externalizing bias in SZ+, whereas SZ− did not significantly differ from healthy controls on this dimension. The personalizing bias was not influenced b...
Source: Schizophrenia Research: Cognition - February 25, 2016 Category: Psychiatry Source Type: research

Neuropsychological correlates of remission in chronic schizophrenia subjects: The role of general and task-specific executive processes
Conclusion The present findings suggest that executive function deficits are present in chronic schizophrenic patients. In addition, specific executive processes might be associated to symptom remission. Future studies examining prospectively first-episode, drug naive patients diagnosed with schizophrenia may be especially elucidative. (Source: Schizophrenia Research: Cognition)
Source: Schizophrenia Research: Cognition - February 16, 2016 Category: Psychiatry Source Type: research

Paranoid individuals with schizophrenia show greater social cognitive bias and worse social functioning than non-paranoid individuals with schizophrenia
Publication date: March 2016 Source:Schizophrenia Research: Cognition, Volume 3 Author(s): Amy E. Pinkham, Philip D. Harvey, David L. Penn Paranoia is a common symptom of schizophrenia that may be related to how individuals process and respond to social stimuli. Previous investigations support a link between increased paranoia and greater social cognitive impairments, but these studies have been limited to single domains of social cognition, and no studies have examined how paranoia may influence functional outcome. Data from 147 individuals with schizophrenia were used to examine whether actively paranoid and no...
Source: Schizophrenia Research: Cognition - January 15, 2016 Category: Psychiatry Source Type: research