The effect of cognitive training on evoked potentials in schizophrenia
Publication date: December 2014 Source:Schizophrenia Research: Cognition, Volume 1, Issue 4 Author(s): Daniela Kariofillis , Gudrun Sartory , Christian Kärgel , Bernhard W. Müller Electrophysiological indices are sensitive to cognitive dysfunction in schizophrenia but have rarely been used to assess benefits of cognitive remediation. Our aim was to evaluate the effect of specific cognitive training approaches on event-related potentials. Forty-six patients with schizophrenia underwent either auditory (AUD) or visuo-spatial (VIS) cognitive training or treatment-as-usual (TAU). Cognitive training was computer-assis...
Source: Schizophrenia Research: Cognition - December 9, 2014 Category: Psychiatry Source Type: research
Positive and negative subclinical symptoms and MCCB performance in non-psychiatric controls
Publication date: December 2014 Source:Schizophrenia Research: Cognition, Volume 1, Issue 4 Author(s): Cole Korponay , George C. Nitzburg , Anil K. Malhotra , Pamela DeRosse Considerable data support the phenomenological and temporal continuity between subclinical psychosis and psychotic disorders. In recent years, neurocognitive deficits have increasingly been recognized as a core feature of psychotic illness but there are few data seeking to elucidate the relationship between subclinical psychosis and neurocogntive deficits in non-clinical samples. The goal of the present study was to examine the relationship bet...
Source: Schizophrenia Research: Cognition - December 9, 2014 Category: Psychiatry Source Type: research
Social cognition and social judgment in schizophrenia
Publication date: December 2014 Source:Schizophrenia Research: Cognition, Volume 1, Issue 4 Author(s): Robyn Langdon , Michael H. Connors , Emily Connaughton Schizophrenia typically involves poor social functioning. This may be due, in part, to deficits in theory-of-mind, the cognitive ability to reason flexibly about the mental states of others. Patients also have deficits in social knowledge. It is currently unclear how these two impairments interrelate in schizophrenia. To address this issue, 43 patients with schizophrenia and 25 healthy controls completed two theory-of-mind tests and a novel test of social judgm...
Source: Schizophrenia Research: Cognition - December 9, 2014 Category: Psychiatry Source Type: research
Overconfidence in incorrect perceptual judgments in patients with schizophrenia
Discussion To the best of our knowledge, this is the first study to demonstrate overconfidence in errors among individuals with psychosis using a visual perception task. Speaking to the specificity of this abnormality for schizophrenia and its pathogenetic relevance, overconfidence in errors and knowledge corruption were elevated in patients with schizophrenia relative to both control groups and were correlated with paranoia. (Source: Schizophrenia Research: Cognition)
Source: Schizophrenia Research: Cognition - December 9, 2014 Category: Psychiatry Source Type: research
The course and correlates of everyday functioning in schizophrenia
This study examined changes in real-world functioning in a sample of people with schizophrenia who varied in their history of long-term institutionalization and related changes in real world functioning to changes in cognition and functional capacity over the follow-up period. Older patients with schizophrenia (n=111) were examined with assessments of cognitive functioning, functional capacity, clinical symptoms, and everyday functioning. They were then followed up to 45 months and examined up to two times. Mixed-model regression was used to examine changes in real-world functioning in social, everyday living, and vocation...
Source: Schizophrenia Research: Cognition - November 6, 2014 Category: Psychiatry Source Type: research
The course of vocational functioning in patients with schizophrenia: Re-examining social drift
In this study, we examined two separate samples of people with schizophrenia who differed in their educational and social backgrounds. We compared personal and maternal education in people with schizophrenia attending an outpatient rehabilitation facility (n = 57) or receiving outpatient services at a VA medical center (n = 39). The sample as a whole showed evidence of decline in vocational status from their best job to their most recent job. Patients attending a rehabilitation facility had completed less education than their mothers, while the VA patients completed more. Differences between personal and maternal education...
Source: Schizophrenia Research: Cognition - November 6, 2014 Category: Psychiatry Source Type: research
Qualitative analysis of interviews of future non-affective psychotic disorder patients and non-psychiatric controls: preliminary results
Conclusions The findings of this unique historical-prospective qualitative analysis of interviews performed before the onset of psychosis, confirmed previous findings of premorbid abnormality of future non-affective psychosis patients. Using qualitative analysis enabled obtaining a more in-depth understanding of the real-life experience of the premorbid period among patients with non-affective psychotic disorders. (Source: Schizophrenia Research: Cognition)
Source: Schizophrenia Research: Cognition - November 6, 2014 Category: Psychiatry Source Type: research
Economic considerations of cognition and functional outcomes in patients with schizophrenia: A systematic literature review
Conclusions Despite the growing scientific literature relating CIAS to adverse outcomes, the translation of outcomes into economic outcomes is seldom reported. Should novel pharmacotherapies and/or psychosocial treatments require reimbursement from health authorities and/or other payers, many gaps warrant attention in order to demonstrate the economic value of these therapies. (Source: Schizophrenia Research: Cognition)
Source: Schizophrenia Research: Cognition - November 6, 2014 Category: Psychiatry Source Type: research
Virtual reality functional capacity assessment in schizophrenia: Preliminary data regarding feasibility and correlations with cognitive and functional capacity performance
Conclusion These results provide support for the possibility of computerized functional capacity assessment, but more substantial studies are required. (Source: Schizophrenia Research: Cognition)
Source: Schizophrenia Research: Cognition - November 6, 2014 Category: Psychiatry Source Type: research
A novel, online social cognitive training program for young adults with schizophrenia: A pilot study
Conclusion This study provides an initial proof of concept for online social cognition training in schizophrenia. This form of training demonstrated feasibility and resulted in within-subject gains in social functioning and motivation. This pilot study represents a first step towards validating this training approach; randomized controlled trials, now underway, are designed to confirm and extend these findings. (Source: Schizophrenia Research: Cognition)
Source: Schizophrenia Research: Cognition - November 6, 2014 Category: Psychiatry Source Type: research
Cognition in schizophrenia: Past, present, and future
Publication date: March 2014 Source:Schizophrenia Research: Cognition, Volume 1, Issue 1 Author(s): Michael F. Green , Philip D. Harvey Schizophrenia Research: Cognition will serve an important function – a place where interests converge and investigators can learn about the recent developments in this area. This new journal will provide rapid dissemination of information to people who will make good use of it. In this initial article, we comment globally on the study of cognition in schizophrenia: how we got here, where we are, and where we are going. The goal of this first article is to place the study of cognit...
Source: Schizophrenia Research: Cognition - November 6, 2014 Category: Psychiatry Source Type: research
Facial emotion recognition impairment is related to disorganisation in multi-episode schizophrenia
Publication date: June 2014 Source:Schizophrenia Research: Cognition, Volume 1, Issue 2 Author(s): Anna Comparelli , Antonella De Carolis , Valentina Corigliano , Giada Trovini , Julia Dehning , Simone Di Pietro , Eleonora De Pisa , Silvana Galderisi , Paolo Girardi The present investigation explores the relationship between facial emotion recognition (FER) and symptom domains in three groups of schizophrenia spectrum patients (43 ultra-high-risk, 50 first episode and 44 multi-episode patients) in which the existence of FER impairment has already been demonstrated. Regression analysis showed that symptoms and ...
Source: Schizophrenia Research: Cognition - November 6, 2014 Category: Psychiatry Source Type: research
Physical performance and disability in schizophrenia
Publication date: June 2014 Source:Schizophrenia Research: Cognition, Volume 1, Issue 2 Author(s): M. Strassnig , J. Signorile , C. Gonzalez , P.D. Harvey Despite 50years of pharmacological and psychosocial interventions, schizophrenia remains one of the leading causes of disability. Schizophrenia is also a life-shortening illness, caused mainly by poor physical health and its complications. The end result is a considerably reduced lifespan that is marred by reduced levels of independence, with few novel treatment options available. Disability is a multidimensional construct that results from different, and often i...
Source: Schizophrenia Research: Cognition - November 6, 2014 Category: Psychiatry Source Type: research
Cognitive predictors of violence in schizophrenia: a meta-analytic review
Conclusions It was concluded that measurement of patients’ global cognitive ability adds incremental variance in the comprehensive assessment and prediction of SZ violence risk. (Source: Schizophrenia Research: Cognition)
Source: Schizophrenia Research: Cognition - November 6, 2014 Category: Psychiatry Source Type: research
The relationship between IQ and performance on the MATRICS consensus cognitive battery
In this study, 250 healthy participants aged 20-69 years were tested with the Wechsler Abbreviated Scale of Intelligence (WASI) and the MATRICS Consensus Cognitive Battery (MCCB). In correlation analyses, IQ was significantly related to all MCCB scores, except the Social Cognition domain. Hierarchical regression analyses including gender, age, and education confirmed this association. For overall cognitive function, 50% of the variance was explained by IQ and demographic characteristics. For the domains Speed of Processing, Working Memory, Visual and Verbal Learning, IQ explained a larger proportion of the variance than th...
Source: Schizophrenia Research: Cognition - November 6, 2014 Category: Psychiatry Source Type: research
