Assessing the potential of longitudinal smartphone based cognitive assessment in schizophrenia: A naturalistic pilot study
DiscussionIt is feasible for those with schizophrenia to use their own smartphones to complete cognitive assessments and other measures related to their mental health. While we did not investigate the correlations between these cognitive assessments and other smartphone captured metrics like step count or self-reported symptoms, the potential to longitudinally assess cognition in the context of patients' environments outside of the clinic presents unique opportunities for characterizing cognitive burden in schizophrenia. (Source: Schizophrenia Research: Cognition)
Source: Schizophrenia Research: Cognition - April 19, 2019 Category: Psychiatry Source Type: research

Differential improvement of negative-symptom subfactors after cognitive remediation in low-functioning individuals with schizophrenia
ConclusionOur findings suggest that CRT has benefits for negative symptoms in very low-functioning patients and that this change may be in part mediated by change in cognitive functions after CRT. (Source: Schizophrenia Research: Cognition)
Source: Schizophrenia Research: Cognition - April 18, 2019 Category: Psychiatry Source Type: research

Emotion-specific performance across empathy tasks in schizophrenia: Influence of metacognitive capacity
This study aimed to: 1) examine emotion-specific performance on an empathy task, and 2) elucidate associations with four metacognitive domains: self-reflectivity, understanding of others' minds, decentration, and mastery. Fifty-seven people with schizophrenia or schizoaffective disorder participated. All were administered a computerized, performance-based measure of empathy and an interview-based measure of metacognitive capacity. Results revealed that, consistent with research on facial affect recognition, participants performed significantly better when recognizing happiness in empathic stimuli than all other emotions. R...
Source: Schizophrenia Research: Cognition - April 18, 2019 Category: Psychiatry Source Type: research

Metacognition moderates the relationship between self-reported and clinician-rated motivation in schizophrenia
DiscussionMetacognition appears to be a key variable impacting the strength of the relationship between self-reported and clinician-rated motivation measures and may help to partly explain the varied relationships observed in prior work. Using a metacognitive framework to guide assessment interviews and targeting metacognition in psychosocial treatments may help to improve the synchrony between self-perceptions and clinician ratings of motivation. (Source: Schizophrenia Research: Cognition)
Source: Schizophrenia Research: Cognition - April 18, 2019 Category: Psychiatry Source Type: research

Visualizing mental representations in schizophrenia patients: A reverse correlation approach
Conclusion: These novel findings provide a proof of principle that the reverse correlation technique can be applied to investigate mental representations in schizophrenia patients. (Source: Schizophrenia Research: Cognition)
Source: Schizophrenia Research: Cognition - April 7, 2019 Category: Psychiatry Source Type: research

Social skills, executive functioning and social engagement
Publication date: September 2019Source: Schizophrenia Research: Cognition, Volume 17Author(s): Nir Madjar, Elena Chubarov, Gil Zalsman, Mark Weiser, Gal ShovalAbstractThe study explored hypothesized mediation of social interaction skills between executive functions and social engagement among adolescents diagnosed with schizophrenia. Participants (N = 92; 62% boys; age = 16.8) were assessed four weeks after hospitalization using previously validated scales. A regression mediation analysis followed by Structural Equation Modeling (SEM; with bootstrap analysis) supported the hypothesis. Executive functions were signi...
Source: Schizophrenia Research: Cognition - April 6, 2019 Category: Psychiatry Source Type: research

Cognitive impairment and its improvement after six months in adolescents with schizophrenia
ConclusionsWe observed cognitive impairments on schizophrenic adolescents, which improved after six months of treatment in almost all domains. (Source: Schizophrenia Research: Cognition)
Source: Schizophrenia Research: Cognition - March 27, 2019 Category: Psychiatry Source Type: research

Association of genetic variants at 22q11.2 chromosomal region with cognitive performance in Japanese patients with schizophrenia
Publication date: Available online 26 March 2019Source: Schizophrenia Research: CognitionAuthor(s): Kazufumi Akiyama, Atsushi Saito, Satoshi Saito, Yuji Ozeki, Takashi Watanabe, Kumiko Fujii, Kazutaka ShimodaAbstract22q11.2 heterozygous multigene deletions confer an increased risk of schizophrenia with marked impairment of cognition. We explored whether genes on 22q11.2 are associated with cognitive performance in patients with idiopathic schizophrenia. A total of 240 schizophrenia patients and 240 healthy controls underwent the Japanese-language version of the Brief Assessment of Cognition in Schizophrenia (BACS) and were...
Source: Schizophrenia Research: Cognition - March 26, 2019 Category: Psychiatry Source Type: research

Disturbed time experience during and after psychosis
Publication date: Available online 21 March 2019Source: Schizophrenia Research: CognitionAuthor(s): D.H.V. Vogel, T. Beeker, T. Haidl, C. Kupke, M. Heinze, K. VogeleyAbstractDisturbances in time experience have been argued to play a significant, if not causative role in the clinical presentation of schizophrenia. Phenomenological considerations suggest a fragmented or dis-articulated time experience causing both primary symptoms such as hallucinations, delusions, and self-disorders, as well as an intersubjective desynchronization. We employed content analysis on material collected from patients diagnosed with schizophrenia...
Source: Schizophrenia Research: Cognition - March 21, 2019 Category: Psychiatry Source Type: research

The continuing story of schizophrenia and schizoaffective disorder: One condition or two?
This study asked whether schizophrenia and schizoaffective disorder are distinguishable on selected cognitive, social cognitive and structural social brain measures. Outpatients with a diagnosis of schizophrenia (n = 44) or schizoaffective disorder (n = 29) and non-psychiatric control participants (n = 62) were studied. Patients were assessed clinically (Positive and Negative Syndrome Scale) and all participants were administered a battery of cognitive (MATRICS Consensus Cognitive Battery; Wechsler Abbreviated Scale of Intelligence, Wide Range Achievement Reading) and social cognitive (Reading the Mind in the E...
Source: Schizophrenia Research: Cognition - February 11, 2019 Category: Psychiatry Source Type: research

Confidence, performance, and accuracy of self-assessment of social cognition: A comparison of schizophrenia patients and healthy controls
This study examines the correlations between performance on a social cognitive test, confidence in performance, effort allocated to the task, and correlates of confidence in patients with schizophrenia and healthy controls (HC). Measures included self-reports of depression, social cognitive ability, and social functioning. A performance-based emotion recognition test assessed social cognitive performance and provided the basis for confidence judgments. Although schizophrenia patients had reduced levels of overall confidence, there was a substantial subset of schizophrenic patients who manifested extreme overconfidence and ...
Source: Schizophrenia Research: Cognition - February 8, 2019 Category: Psychiatry Source Type: research

Limited changes in activities of daily life performance ability among people with schizophrenia at clinical settings and the factors moderating the changes
ConclusionsImpairment of ADL ability is recalcitrant in schizophrenia. The improvement was modest and occurred only in a proportion of participants. However, promisingly, chronic illness, low baseline ADL ability, treatment with clozapine and presence of treatment-resistant schizophrenia did not have an adverse effect on the outcome. (Source: Schizophrenia Research: Cognition)
Source: Schizophrenia Research: Cognition - January 17, 2019 Category: Psychiatry Source Type: research

Modified Work Behavior Inventory assessment: Evaluation of psychometric properties
Publication date: June 2019Source: Schizophrenia Research: Cognition, Volume 16Author(s): Jason E. Peer, Joanna E. Strong Kinnaman, Wendy N. TenhulaAbstractThe Work Behavior Inventory (WBI) is a widely used and validated assessment of work functioning in people with schizophrenia. WBI ratings are based on workplace observation and interview with work supervisors. Workplace observation may not be acceptable in all employment settings. A WBI assessment based only on supervisor interview may offer more utility. The current study evaluated the psychometric properties of a modified WBI among individuals with schizophrenia parti...
Source: Schizophrenia Research: Cognition - January 10, 2019 Category: Psychiatry Source Type: research

Neurological soft signs (NSS) and cognitive impairment in chronic schizophrenia
Publication date: June 2019Source: Schizophrenia Research: Cognition, Volume 16Author(s): Christina J. Herold, Céline Z. Duval, Marc M. Lässer, Johannes SchröderAbstractRecent studies indicate that neurological soft signs (NSS) in schizophrenia are associated with generalized cognitive impairments rather than changes in specific neuropsychological domains. However, the majority of studies solely included first-episode patients or patients with a remitting course and did not consider age, course, education or severity of global cognitive deficits as potential confounding variables. Therefore, we examined NSS with respect...
Source: Schizophrenia Research: Cognition - December 22, 2018 Category: Psychiatry Source Type: research

The role of childhood trauma in cognitive performance in schizophrenia and bipolar disorder – A systematic review
Publication date: June 2019Source: Schizophrenia Research: Cognition, Volume 16Author(s): Maria R. Dauvermann, Gary DonohoeAbstractChildhood trauma (CT) has repeatedly been associated with cognitive deficits in patients with psychosis but many inconsistencies have been reported so that the nature of the relationship remains unclear. The purpose of this review was to better characterize the contribution of CT to cognitive deficits by considering the type, severity and frequency of childhood traumatic events and their relationships with psychosis at all stages.Relevant studies were identified via electronic and manual litera...
Source: Schizophrenia Research: Cognition - December 12, 2018 Category: Psychiatry Source Type: research