New normal limits for pediatric ECG in childhood obesity? Influence of childhood obesity on the ECG
Studies demonstrated abnormal ECG phenomena in adult obese patients. Although some of these phenomena are clearly pathologic, for others the clinical relevance is less clear. In children this conflict is even harder to address as there are only scarce specific reference data on ECG in childhood obesity.The aim of this study was to investigate the influence of childhood obesity on distinct ECG parameters of cardiac activation and repolarization in a cohort of otherwise healthy obese volunteers and compare these with lean controls. (Source: Progress in Pediatric Cardiology)
Source: Progress in Pediatric Cardiology - November 28, 2017 Category: Cardiology Authors: C. Paech, M. Anhalt, R.A. Gebauer, F. Wagner, M. Vogel, T. Kirsten, M. Weidenbach, W. Kiess, I. D ähnert, A. Körner Source Type: research
WITHDRAWN: Cardiac Complications in Patients with Thalassemia Major in Iran: A Meta-Analysis Study
This article has been withdrawn at the request of the author(s) and/or editor. The Publisher apologizes for any inconvenience this may cause. (Source: Progress in Pediatric Cardiology)
Source: Progress in Pediatric Cardiology - October 18, 2017 Category: Cardiology Authors: Kourosh Sayehmiri, Gholamreza Badfar, Masoumeh Shohani, Ali Soleymani, Milad Azami Source Type: research
Serial assessment of brain natriuretic peptide in single ventricle patients with a hybrid stage 1 palliation
Brain natriuretic peptide (BNP) has been used as a marker for heart failure. Cross-sectional studies have documented differences in BNP levels in patients with single ventricle physiology but the utility of longitudinal samples has not been established. We hypothesized that change in BNP would correlate with change in clinical status in single ventricle patients palliated with a hybrid stage 1 palliation. Retrospective Ross heart failure score, inotrope score, lactate, and creatinine were obtained at time of each BNP. (Source: Progress in Pediatric Cardiology)
Source: Progress in Pediatric Cardiology - October 18, 2017 Category: Cardiology Authors: Christina M. Phelps, Corey Stiver, Tracy Heard, Karen M. Texter, Andrew R. Yates Source Type: research
WITHDRAWN: Cardiac Complications in Patients with Thalassemia Major in Iran: A Meta-Analysis Study
This article has been withdrawn at the request of the author(s) and/or editor. The Publisher apologizes for any inconvenience this may cause. (Source: Progress in Pediatric Cardiology)
Source: Progress in Pediatric Cardiology - October 18, 2017 Category: Cardiology Authors: Kourosh Sayehmiri, Gholamreza Badfar, Masoumeh Shohani, Ali Soleymani, Milad Azami Source Type: research
Cardiac complications in patients with thalassemia major in Iran: A meta-analysis
This study aims to assess cardiac complications in patients with thalassemia major in Iran.This study was conducted based on PRISMA guidelines for systematic review and meta-analysis studies. To find the relevant literature, a comprehensive search was conducted in several databases including SID, Magiran, Iranmedex, IranDoc, Medlib, PubMed, Scopus, Science Direct, Web of Science, and Google Scholar search engine. (Source: Progress in Pediatric Cardiology)
Source: Progress in Pediatric Cardiology - October 18, 2017 Category: Cardiology Authors: Kourosh Sayehmiri, Gholamreza Badfar, Masoumeh Shohani, Ali Soleymani, Milad Azami Source Type: research
Cardiac complications in patients with thalassemia major in Iran: A meta-analysis study
This study aims to assess cardiac complications in patients with thalassemia major in Iran.This study was conducted based on PRISMA guidelines for systematic review and meta-analysis studies. To find the relevant literature, a comprehensive search was conducted in several databases including SID, Magiran, Iranmedex, IranDoc, Medlib, PubMed, Scopus, Science Direct, Cochrane, Web of Science, and Google Scholar search engine. (Source: Progress in Pediatric Cardiology)
Source: Progress in Pediatric Cardiology - October 18, 2017 Category: Cardiology Authors: Kourosh Sayehmiri, Gholamreza Badfar, Masoumeh Shohani, Ali Soleymani, Milad Azami Source Type: research
Serial assessment of brain natriuretic peptide in single ventricle patients with a hybrid stage 1 palliation
Brain natriuretic peptide (BNP) has been used as a marker for heart failure. Cross-sectional studies have documented differences in BNP levels in patients with single ventricle physiology but the utility of longitudinal samples has not been established. We hypothesized that change in BNP would correlate with change in clinical status in single ventricle patients palliated with a hybrid stage 1 palliation. Retrospective Ross heart failure score, inotrope score, lactate, and creatinine were obtained at time of each BNP. (Source: Progress in Pediatric Cardiology)
Source: Progress in Pediatric Cardiology - October 18, 2017 Category: Cardiology Authors: Christina M. Phelps, Corey Stiver, Tracy Heard, Karen M. Texter, Andrew R. Yates Source Type: research
Optimizing surgical placement of the HeartWare ventricular assist device in children and adolescents by virtual implantation
In order to safely place adult-size intracorporeal devices into small patients, innovative techniques such as virtual implantation are necessary to assess proper fit. We assessed the hypothesis that virtual implantation of the HeartWare ventricular assist device will facilitate safe placement in patients at or below industry size guidelines. (Source: Progress in Pediatric Cardiology)
Source: Progress in Pediatric Cardiology - October 16, 2017 Category: Cardiology Authors: Ryan A. Moore, Gavin A. D'Souza, Chet Villa, Michael D. Taylor, David L.S. Morales, Angela Lorts Source Type: research
Progress in Pediatric Cardiology: SI Pediatric VAD
The use of mechanical circulatory support (MCS) in the form of ventricular assist devices (VAD) has evolved from purely a heroic measure to an established therapy for end stage heart failure refractory to maximal medical support. The advent of smaller implantable devices designed for and tested in adults, but applicable for use in children, has heralded a significant expansion in device utilization and shift towards earlier device use in less critically ill children as a bridge to transplantation. (Source: Progress in Pediatric Cardiology)
Source: Progress in Pediatric Cardiology - October 11, 2017 Category: Cardiology Tags: Preface Source Type: research
Neurohormonal targets in the treatment of pediatric heart failure
The history of the clinical approach to heart failure has been notable for a series of evolving conceptual paradigms, each in an effort to explain the clinical syndrome that presents. With the recent emphasis on a neurohormonal model of heart failure, we have seen the development of new therapeutic options that target biologically active molecules to preserve myocardial function. Sacubitril-valsartan, a combined angiotensin-neprilysin inhibitor shows the greatest clinical promise, while there is less evidence to support the use of recombinant relaxin-2 or vasopressin antagonists. (Source: Progress in Pediatric Cardiology)
Source: Progress in Pediatric Cardiology - October 10, 2017 Category: Cardiology Authors: Jonathan B. Edelson, Joseph W. Rossano Tags: Review Source Type: research
Genetics of pediatric cardiomyopathies
Genetic testing in children with cardiomyopathies can be helpful to confirm the diagnosis and clarify prognosis, determine if treatments are available such as for inborn errors of metabolism, and identify need for additional subspecialist medical care or surveillance such as occurs in many syndromic cardiomyopathies. Genetic testing also provides information to stratify risk for other family members, provide recurrence risk, and identify families that may consider options for family planning. In the future there may also be prevention and treatment strategies for individuals with pathogenic variants in sarcomere and other ...
Source: Progress in Pediatric Cardiology - October 6, 2017 Category: Cardiology Authors: Wendy K. Chung, Carolyn Ho, Teresa Lee, Christine E. Seidman, Stephanie M. Ware Tags: Review Source Type: research
A perfect storm: Understanding hemostasis, coagulation and inflammation with artificial material
Mechanical circulatory support (MCS) devices have revolutionized the treatment of acute and chronic heart failure in both the pediatric and adult communities over the past decades, but they are not without complications. The presence of a foreign body, especially within the vasculature, evokes a response by the body to try to rid itself of the invader via myriad mechanisms that include the coagulation system, the innate immune system and even the adaptive immune system. While these responses have allowed us (and other species) to survive to this day, they pose a particular challenge to the safe and effective use of implant...
Source: Progress in Pediatric Cardiology - October 5, 2017 Category: Cardiology Authors: Robert F. Padera Tags: Review Source Type: research
