Pulmonary artery stenosis due to embryonal carcinoma with primary mediastinal location.
Abstract
A 29-year old man was admitted to the intensive care unit after losing consciousness. On physical examination, a loud systolic murmur over the heart was found. Echocardiography revealed narrowing of pulmonary artery with high pressure gradient. Computed tomography of the chest revealed the presence of large tumour localised in the upper anterior mediastinum. Due to the risk of total closure of the pulmonary artery, interventional mediastinotomy was performed and diagnosis of carcinoma embryonale was established. Subsequent chemotherapy (BEP regimen) has brought regression of tumour and significant...
Source: Pneumonologia i Alergologia Polska - March 13, 2015 Category: Respiratory Medicine Authors: Grzegorczyk F, Dybowska M, Kuca P, Czajka C, Burakowski J, Langfort R, Orłowski T, Tomkowski W Tags: Pneumonol Alergol Pol Source Type: research
Thixotropy of nasal medications - its role in clinical practice.
Abstract
Optimal medication should be characterized by good bioavailability, rapid onset of action, a long period of therapeutic activity, with preserved high safety profile and the lowest possible risk of side effects. Therefore, in addition to traditional drug administration routes, such as oral or injection, novel methods for drug applications, for example in the form of a nasal application have been developed. Because of the anatomy of the nose, drugs administered intranasally can be rapidly absorbed and, depending on the nature of the active substance, may act locally on the mucosa or can have a signi...
Source: Pneumonologia i Alergologia Polska - March 13, 2015 Category: Respiratory Medicine Authors: Koźmiński M, Kupczyk M Tags: Pneumonol Alergol Pol Source Type: research
Cardiovascular safety of two bronchodilators' fixed-dose combination: indacaterol and glycopyrronium.
Abstract
Combination therapy with anticholinergics and b2-agonists should be used in COPD patients after failure of previous monotherapy with one of these drugs. Synergistic effect of both mechanisms of bronchodilation can maximize the efficacy of separately administered drugs. The effectiveness of the combination of LABA and LAMA is already confirmed, nevertheless the question about the safety profile of this therapy is still remaining, particularly with regard to the cardiovascular system. The paper discusses the overall safety profile of the combined preparation compare to placebo as well as the active ...
Source: Pneumonologia i Alergologia Polska - March 13, 2015 Category: Respiratory Medicine Authors: Kozielski J Tags: Pneumonol Alergol Pol Source Type: research
Chronic obstructive pulmonary disease in the awareness of Polish society. Report from the public opinion survey by the Polish Respiratory Society and TNS Polska.
CONCLUSIONS: There is an urgent need for widespread public education on preventive measures. Study results support the need of educating both healthy subjects and patients with COPD as to how effectively reduce the risk of developing the disease. One third of all respondents has no assumptions in this regard (i.e. explicitly declares having no knowledge at all on the subject), and more than 40% subjects have various misconceptions. Educators should therefore spread information about the disease but also correct these misconceptions.
PMID: 25577528 [PubMed - in process] (Source: Pneumonologia i Alergologia Polska)
Source: Pneumonologia i Alergologia Polska - January 18, 2015 Category: Respiratory Medicine Authors: Śliwiński P, Puchalski K Tags: Pneumonol Alergol Pol Source Type: research
Fatigue in patients with inactive sarcoidosis does not correlate with lung ventilation ability or walking distance. Pilot Study.
CONCLUSIONS: Fatigue in patients with sarcoidosis does not correlate with the results of lung function tests or with walking distance in 6MWT.
PMID: 25577529 [PubMed - in process] (Source: Pneumonologia i Alergologia Polska)
Source: Pneumonologia i Alergologia Polska - January 18, 2015 Category: Respiratory Medicine Authors: Zieleźnik K, Jastrzębski D, Ziora D Tags: Pneumonol Alergol Pol Source Type: research
Tuberculosis among the homeless and inmates kept in custody and in penitentiary institutions in the Silesia region.
CONCLUSIONS: The health project enabled effective detection of tuberculosis in risk groups and should be continued in the following years. The set of the applied diagnostic methods allowed the detection of in the studied subpopulations people suffering from tuberculosis. Patients were treated with antituberculosis drugs that would stop them from spreading the disease to other people.
PMID: 25577530 [PubMed - in process] (Source: Pneumonologia i Alergologia Polska)
Source: Pneumonologia i Alergologia Polska - January 18, 2015 Category: Respiratory Medicine Authors: Pendzich J, Maksymowicz-Mazur W, Pawłowska J, Filipczyk Ł, Kulawik I, Zientek J, Kozielski J Tags: Pneumonol Alergol Pol Source Type: research
Lung-heart clinical crosstalk in the course of COPD exacerbation.
CONCLUSIONS: Pulmonary hyperinflation and bronchial obstruction may be reduced by effective COPD exacerbation treatment and are accompanied by clinical improvement. The mPAP reduction observed in the course of treatment was not correlated with the results of 6MWT and MRC score.
PMID: 25577531 [PubMed - in process] (Source: Pneumonologia i Alergologia Polska)
Source: Pneumonologia i Alergologia Polska - January 18, 2015 Category: Respiratory Medicine Authors: Skoczyński S, Mizia-Stec K, Semik-Orzech A, Sozańska E, Brożek G, Pierzchała W Tags: Pneumonol Alergol Pol Source Type: research
Bird fancier's lung: clinical-radiological presentation in 15 cases.
CONCLUSIONS: BFL can exhibit a wide range of radiological patterns, and a high index of suspicion must be maintained, with particular attention to detailed exposure history in every case of interstitial lung disease.
PMID: 25577532 [PubMed - in process] (Source: Pneumonologia i Alergologia Polska)
Source: Pneumonologia i Alergologia Polska - January 18, 2015 Category: Respiratory Medicine Authors: Kumar R, Singh M Tags: Pneumonol Alergol Pol Source Type: research
[Primary pulmonary mucosa-associated lymphoid tissue lymphoma: a case report].
We present the case of primary pulmonary mucosa-associated lymphoid tissue lymphoma. A 76-year-old man with a history of heavy smoking (22.5 pack years) was admitted to the hospital for a further diagnostics of an abnormal finding in the right lung visualized on the chest X-ray. The diagnostic process, including imagining studies did not reveal the etiology of a lesion in the right lung. The patient was qualified for surgical diagnostics. The histological finding confirmed extranodal marginal low-grade B-cell lymphoma of mucosa -associated lymphoid tissue.
PMID: 25577533 [PubMed - in process] (Source: Pneumonologi...
Source: Pneumonologia i Alergologia Polska - January 18, 2015 Category: Respiratory Medicine Authors: Kubisa B, Bocheńska A, Piotrowska M, Dec P, Lesińska A, Kubisa A, Wójcik J, Pieróg J, Grodzki T Tags: Pneumonol Alergol Pol Source Type: research
Leflunomide-induced acute interstitial pneumonia in a patient treated for rheumatoid arthritis.
We present a patient with RA treated with leflunomide, in whom leflunomide lung injury had a fatal outcome. Potential risk factors for pulmonary complications of leflunomide treatment and the management of patients with leflunomide lung injury are discussed.
PMID: 25577534 [PubMed - in process] (Source: Pneumonologia i Alergologia Polska)
Source: Pneumonologia i Alergologia Polska - January 18, 2015 Category: Respiratory Medicine Authors: Maskey-Warzęchowska M, Karwat K, Szczepankiewicz B, Langfort R, Szołkowska M, Chazan R Tags: Pneumonol Alergol Pol Source Type: research
[Vascular ring: a rare cause of dyspnea in an elderly male patient. Case report].
Abstract
Shortness of breath (dyspnea) and changes present in X-rays of the chest are most frequent symptoms indicating further pulmonary diagnostic. Presented is the case of 71-year-old patient reffered from general practitioner due to exacerbation of dyspnea and abnormalities present in the chest X-ray.The patient has been treated for ischemic heart disease and arrythmia for a couple of years.Three-dimensional CT of the chest revealed a vascular ring of aorta.It is a defect characterized by a faulty flow of large vascular trunks, which built a cardiovascular ring that partially or completely enricle the ...
Source: Pneumonologia i Alergologia Polska - January 18, 2015 Category: Respiratory Medicine Authors: Orwaldi M Tags: Pneumonol Alergol Pol Source Type: research
[Diagnostic and therapeutic difficulties in mediastinal fibromatosis. Case report].
Abstract
Mediastinal fibromatosis is a very rare mesenchymal tumor originated from fibrous tissue. A case of 26-year old men with mediastinal tumor causes respiratory insufficiency and dysphagia is described. This sympthoms occured due to esophageal impression and infiltration with occlusion of main left bronchus by mediastinal tumor. Ethiology of the tumor was established based on histopathology assesment of the tissue samples taken during explorative thoracotomy after 3 years and many other diagnostic procedures undertaken. The authors describe difficulties in diagnosis of mediastinal tumors, especially ...
Source: Pneumonologia i Alergologia Polska - January 18, 2015 Category: Respiratory Medicine Authors: Wojtyś ME, Alchimowicz J, Waloszczyk P, Wójcik N, Grodzki T Tags: Pneumonol Alergol Pol Source Type: research
[Application of basophil activation test in diagnosing aspirin hypersensitivity].
We present a case of identification of the culprit drug which caused an anaphylactic reaction.
PMID: 25577537 [PubMed - in process] (Source: Pneumonologia i Alergologia Polska)
Source: Pneumonologia i Alergologia Polska - January 18, 2015 Category: Respiratory Medicine Authors: Gawinowska M Tags: Pneumonol Alergol Pol Source Type: research
[Assessment of respiratory function in the qualification for lung cancer surgery].
Abstract
Surgery is the treatment of choice in patients with a diagnosis of non-small cell lung cancer (NSCLC). A pivotal of eligibility for resection is the early stage of the disease and histopathological assessment. The performance status and comorbidities in population, predominated by elderly patients, also influence the therapeutic decisions. In some lung cancer patients COPD coexists, characterized by a decrease in lung function. Then the preoperative evaluation is particularly important, for both the risk of postoperative complications, lung function and quality of life postoperatively. Recently se...
Source: Pneumonologia i Alergologia Polska - January 18, 2015 Category: Respiratory Medicine Authors: Franczuk M, Wesołowski S Tags: Pneumonol Alergol Pol Source Type: research
[New dry powder inhalers].
Abstract
The most recently approved DPI's - Ellipta™ and NEXThaler® are the most modern inhalers on the market. Both are flow independent in the physiological range of flows seen in patients with asthma and/or COPD. Both require three actions (open-load -inhaler) for a successful inhalation. The Ellipta™ inhaler is the first DPI, which enables simultaneous delivery of two compounds without need for co-formulation. NEXThaler® is the only DPI on the market delivering extra fine aerosol (MMAD < 2 μm) of a combined inhalation product of inhaled corticosteroid and long-action b2-agonist. Both have bee...
Source: Pneumonologia i Alergologia Polska - January 18, 2015 Category: Respiratory Medicine Authors: Emeryk A, Pirożyński M Tags: Pneumonol Alergol Pol Source Type: research
