Squamous cell lung cancer in a male with pulmonary tuberculosis.
We present a case report of a 57-year old male with concurrent TB and lung cancer. He was diagnosed with positive sputum smear for acid fast bacilli (AFB) and subsequent culture of Mycobacterium tuberculosis. Besides, his comorbid conditions were chronic hepatitis C virus (HCV) infection and peripheral artery disease (PAD). Later while on anti-tuberculous treatment (ATT) squamous cell lung cancer (SCC) was confirmed with computed tomography (CT) guided biopsy. Due to poor general condition the patient was not fit for either surgery or radical chemo- and radiotherapy. He was transferred to hospice for palliative therapy. We...
Source: Pneumonologia i Alergologia Polska - July 17, 2015 Category: Respiratory Medicine Authors: Skowroński M, Iwanik K, Halicka A, Barinow-Wojewódzki A Tags: Pneumonol Alergol Pol Source Type: research

Self-expandable metallic stents in oesophago-respiratory fistulas treatment in neoplasms - case reports and literature review.
Abstract Self-expandable metallic stents (SEMS) insertion to the oesophagus is the method of choice in palliative treatment of malignant oesophago-respiratory fistulas (ERF). ERF evolve as a result of 0.2-5% of advanced oesopghageal or lung cancer. They also appear after radiotherapy. EFR are serious and lethal complications. SEMS insertion is an effective, safe, technically simple and minimally invasive solution. Potential complications of SEMS include thoracic pain, bleeding, perforation, stent migration, tumour overgrowth or ingrowth and food bolus impaction. The article presents three cases of patients...
Source: Pneumonologia i Alergologia Polska - July 17, 2015 Category: Respiratory Medicine Authors: Marczyński W, Pająk M, Komandowska T, Nikiel I Tags: Pneumonol Alergol Pol Source Type: research

Pulmonary hypertension in the course of diffuse parenchymal lung diseases - state of art and future considerations.
Abstract Lung diseases are one of the most frequent causes of pulmonary hypertension (PH). The development of PH influences the course of lung disease, worsening the clinical symptoms and prognosis. According to the most recent publications, PH in the course of lung diseases develops as a result of both "parenchymal" and vascular pathology, in the patients with genetic predisposition. Prolonged infection (especially viral one) may be an additional promoting factor. Right heart catheterization (RHC), which is an invasive procedure, is the only objective method of diagnosing PH. According to the latest recom...
Source: Pneumonologia i Alergologia Polska - July 17, 2015 Category: Respiratory Medicine Authors: Szturmowicz M, Kacprzak A, Błasińska-Przerwa K, Kuś J Tags: Pneumonol Alergol Pol Source Type: research

The statement of the Polish Society of Allergology experts on the treatment of difficult-to-treat asthma.
Abstract The main objective of asthma treatment is to control symptoms of the disease; however, despite the availability of guidelines and many groups of medications, the degree of control of this condition is insufficient. In difficult-to-treat asthma, the optimal control cannot be achieved due to reasons independent of the disease. Factors worsening asthma control include: inadequate treatment plan (low therapy adherence and compliance), inappropriate inhalation technique, insufficient symptom control using the available classes of medications, incomplete response to treatment (non-responders, steroid-re...
Source: Pneumonologia i Alergologia Polska - July 17, 2015 Category: Respiratory Medicine Authors: Bodzenta-Łukaszyk A, Fal AM, Jassem E, Kowalski ML, Kuna P, Kupczyk M Tags: Pneumonol Alergol Pol Source Type: research

The statement of the Polish Society of Allergology regarding necessary changes in therapeutic program of severe IgE-mediated allergic asthma with omalizumab.
PMID: 26166795 [PubMed - in process] (Source: Pneumonologia i Alergologia Polska)
Source: Pneumonologia i Alergologia Polska - July 17, 2015 Category: Respiratory Medicine Authors: Bartuzi Z, Bodzenta-Łukaszyk A, Kuna P, Kupryś-Lipińska I, Niżankowska-Mogilnicka E, Samoliński B Tags: Pneumonol Alergol Pol Source Type: research

Anaphylaxis.
PMID: 26050976 [PubMed - in process] (Source: Pneumonologia i Alergologia Polska)
Source: Pneumonologia i Alergologia Polska - June 10, 2015 Category: Respiratory Medicine Authors: Kruszewski J Tags: Pneumonol Alergol Pol Source Type: research

Epidemiology of asthma in Poland in urban and rural areas, based on provided health care services.
CONCLUSIONS: The average prevalence rate for rural areas is significantly lower than for urban areas. The use of adjusted incidence rate leads to the conclusion that the number of sufferers in urban areas is higher (about 10%) of the number of sufferers in the rural areas. The results of the analysis are consistent with information from previous studies in Poland and in the world. PMID: 26050977 [PubMed - in process] (Source: Pneumonologia i Alergologia Polska)
Source: Pneumonologia i Alergologia Polska - June 10, 2015 Category: Respiratory Medicine Authors: Śliwczyński A, Brzozowska M, Iltchew P, Czeleko T, Kucharczyk A, Jędrzejczyk T, Jahnz-Różyk K, Marczak M Tags: Pneumonol Alergol Pol Source Type: research

Anaphylaxis as a cause of hospitalization - a single academic centre experience.
CONCLUSIONS: It is difficult to forecast the course of the reaction based on the causative factor, for anaphylactic reaction is characterised by a great individual changeability and intensity of the first symptoms. PMID: 26050978 [PubMed - in process] (Source: Pneumonologia i Alergologia Polska)
Source: Pneumonologia i Alergologia Polska - June 10, 2015 Category: Respiratory Medicine Authors: Baran K, Pałgan K, Szortyka M, Bitner A, Bartuzi Z, Klawe JJ Tags: Pneumonol Alergol Pol Source Type: research

Causes of deaths in COPD patients in primary care setting - a 6-year follow-up.
CONCLUSIONS: Study performed six years after COPD diagnosis revealed that 23.5% of subjects died. The main causes of deaths were the following: cardiovascular diseases (mainly heart attack and stroke), COPD exacerbations and lung cancer (more than 75%). Death risk in COPD patients was associated with age, male sex, dyspnoea and severity of the disease. PMID: 26050979 [PubMed - in process] (Source: Pneumonologia i Alergologia Polska)
Source: Pneumonologia i Alergologia Polska - June 10, 2015 Category: Respiratory Medicine Authors: Pływaczewski R, Maciejewski J, Bednarek M, Zieliński J, Górecka D, Śliwiński P Tags: Pneumonol Alergol Pol Source Type: research

High-mobility group box 1 protein levels in serum of subjects after exposure to fire smoke - short communication.
CONCLUSION: As indicated, an acute exposure to smoke may lead to transient increase of HMGB1 in serum in exposed subjects. Further studies are necessary in order to confirm the importance of this protein in pathogenesis of acute airway injury due to exposure to fire smoke. PMID: 26050980 [PubMed - in process] (Source: Pneumonologia i Alergologia Polska)
Source: Pneumonologia i Alergologia Polska - June 10, 2015 Category: Respiratory Medicine Authors: Krakowiak A, Śliwkiewicz K, Nowakowska-Swirta E, Winnicka R, Politański P Tags: Pneumonol Alergol Pol Source Type: research

Bronchioloalveolar cell carcinoma presenting as a "non-resolving consolidation" for two years.
We present a case of a middle aged female who was evaluated for a "non-resolving consolidation" for a period of two years. She had undergone an inconclusive bronchoscopy and had received several courses of antibiotics including anti-tuberculous therapy without relief. The size of the lesion had remained largely unchanged during this period and there was no significant clinical deterioration in the patient. Transbronchial biopsy done on presentation revealed BAC of the mucinous variety. BAC presenting as a large consolidation without significant change for a period of two years has rarely been documented in the literature. ...
Source: Pneumonologia i Alergologia Polska - June 10, 2015 Category: Respiratory Medicine Authors: Mir E, Sareen R, Kulshreshtha R, Shah A Tags: Pneumonol Alergol Pol Source Type: research

Synchronous two distinct neuroendocrine lung cancer lesions.
We present the case of a 55-year-old woman with synchronous two distinct neuroendocrine lung cancer lesions in the right upper lobe. Initially she showed no signs or symptoms related to lung lesions and was admitted to Thoracic Surgery Ward for the investigation of two oval, solitary pulmonary nodules (11 and 19 mm in diameter) detected on a chest X-ray performed three months earlier. The radiological imaging showed a variability of growth of both lesions (smaller tumor has enlarged while the larger one remained unchanged). After the CT-guided lung biopsy, patient underwent right upper lobectomy. Histological examination r...
Source: Pneumonologia i Alergologia Polska - June 10, 2015 Category: Respiratory Medicine Authors: Rydel M, Czyżewski D, Stęplewska K, Zygo A, Adamek M Tags: Pneumonol Alergol Pol Source Type: research

Acute laryngeal dyspnea as first presentation of granulomatosis with polyangiitis.
We report a rare case of acute laryngeal dyspnea and rapidly progressive pulmonary changes as first manifestations of disease. A 53 year-old woman presented with symptoms of two-week dyspnea, which aggravated rapidly in the preceding hours. Laryngological examination revealed subglottic infiltrations and vocal fold oedema which required urgent tracheotomy. During few days she developed gingival ulcerations and pulmonary infiltration with negative serum c-ANCA titers. The histopathological examination of subglottic and gingival biopsies and the clinical picture established the diagnosis of GPA. She was treated with predniso...
Source: Pneumonologia i Alergologia Polska - June 10, 2015 Category: Respiratory Medicine Authors: Pajor AM, Kwiatkowska S, Kroczyńska-Bednarek J, Piotrowski WJ Tags: Pneumonol Alergol Pol Source Type: research

The role of questionnaires in the assessment of asthma control.
Abstract The achievement and the maintenance of asthma control is currently considered the main goal of asthma treatment. Recent guidelines recommend regular assessment of asthma control and indicate questionnaires as important tools that can facilitate its evaluation. Questionnaires relate to GINA or NAEPP guidelines. Questionnaires constitute complex numerical or categorical scales and consist of several to over a dozen questions relating to the patient's symptoms of asthma, limitations in daily activities and usage of rescue medications within a period of time. Each questionnaire is characterized by the...
Source: Pneumonologia i Alergologia Polska - June 10, 2015 Category: Respiratory Medicine Authors: Przybyszowski M, Bochenek G Tags: Pneumonol Alergol Pol Source Type: research

Tiotropium and its efficacy in the treatment of COPD.
Abstract Exacerbations of chronic obstructive pulmonary disease (COPD) have a negative effect on the clinical course and outcome of the disease thus causing considerable social and economic burden. As the natural course of the disease may vary, the treatment should take into account an individual approach to a patient. The appropriate treatment makes it possible to control the symptoms, improves effort tolerance and decreases the risk of exacerbations and death. Tiotropium is a muscarinic receptor antagonist, which is taken once daily, in maintenance therapy, in every stage of the disease progress. The eff...
Source: Pneumonologia i Alergologia Polska - June 10, 2015 Category: Respiratory Medicine Authors: Kupczyk M, Szepiel P, Kuna P Tags: Pneumonol Alergol Pol Source Type: research