Coexistence of sarcoidosis with seminoma - a case report.
Abstract A 30-year-old patient, with diagnosis of seminoma (T1 Nx Mx) was treated radically with orchidectomy. In chest CT performed postoperatively numerous diffuse nodules were revealed in both lungs. Lesions were situated particularly in the upper and middle pulmonary zones. In order to verify the nature of pulmonary abnormalities videothoracoscopy of the right pleural cavity was performed with specimen collection. Histopathological examination excluded the possibility of cancer metastases to pulmonary parenchyma and revealed the presence of sarcoid-like granulomas. Coexistence of seminoma and diff...
Source: Pneumonologia i Alergologia Polska - February 22, 2013 Category: Respiratory Medicine Authors: Kita-Milczarska K, Górska L, Kuziemski K, Sejda A, Jassem E, Biernat W Tags: Pneumonol Alergol Pol Source Type: research

Cardiac tamponade as the first symptom of lung cancer.
Abstract Pericardial effusion is a relatively common clinical problem. It is, however, rarely the first symptom of cancer. Cardiac tamponade testifies to an advanced stage of cancer and is a negative prognostic factor. This paper presents a patient in whom cardiac tamponade was the first symptom of lung cancer. A 63-year-old male, habitual smoker, was admitted to hospital due to progressive symptoms of exertional dyspnoea lasting for a few days and chest pain. Echocardiographic examination revealed a large amount of fluid in the pericardium with echocardiographic signs of a life-threatening cardiac tam...
Source: Pneumonologia i Alergologia Polska - February 22, 2013 Category: Respiratory Medicine Authors: Gromadziński L, Przelaskowski P, Januszko-Giergielewicz B, Górny J, Stankiewicz A, Każarnowicz A, Pruszczyk P Tags: Pneumonol Alergol Pol Source Type: research

New therapeutic possibilities - COPD.
PMID: 23420433 [PubMed - in process] (Source: Pneumonologia i Alergologia Polska)
Source: Pneumonologia i Alergologia Polska - February 22, 2013 Category: Respiratory Medicine Authors: Chazan R Tags: Pneumonol Alergol Pol Source Type: research

Advances in pulmonology in year 2012.
PMID: 23420434 [PubMed - as supplied by publisher] (Source: Pneumonologia i Alergologia Polska)
Source: Pneumonologia i Alergologia Polska - February 22, 2013 Category: Respiratory Medicine Authors: Chorostowska-Wynimko J, Demkow U, Górski P, Krenke K, Kurzyna M, Kuś J, Langfort R, Maszkowska-Kopij K, Roszkowski-Śliż K, Skorupa6 W, Sobczyńska-Tomaszewska A, Szołkowska M, Torbicki A Tags: Pneumonol Alergol Pol Source Type: research

Hypercalcemia and renal failure in the course of sarcoidosis.
PMID: 23420435 [PubMed - in process] (Source: Pneumonologia i Alergologia Polska)
Source: Pneumonologia i Alergologia Polska - February 22, 2013 Category: Respiratory Medicine Authors: Kozielski J Tags: Pneumonol Alergol Pol Source Type: research

Report of scientific session celebrating 100 years of laboratory in Rudka.
PMID: 23420436 [PubMed - in process] (Source: Pneumonologia i Alergologia Polska)
Source: Pneumonologia i Alergologia Polska - February 22, 2013 Category: Respiratory Medicine Authors: Zielonka TM Tags: Pneumonol Alergol Pol Source Type: research

[Staging of non-small cell lung cancer using CT and integrated PET-CT.]
Abstract Introduction. Lung cancer is the leading cause of death from cancer in developed countries. Radiological imaging methods are the basic methods in early diagnosis of this disease. TNM classification is a very important tool for optimal treatment in non-small lung cancer (NSCLC). Conventional radiological techniques allow the evaluation of the stage on the basis of anatomical changes only, while PET-CT provides information about the biochemical processes that may precede anatomical changes. The aim of this study was to compare the accuracy and sensitivity of CT and PET-CT in the staging of NSCLC...
Source: Pneumonologia i Alergologia Polska - January 17, 2013 Category: Respiratory Medicine Authors: Opoka L, Kunikowska J, Podgajny Z, Błasińska-Przerwa K, Burakowska B, Oniszh K, Gola M, Langfort R, Rudziński P, Bestry I, Roszkowski-Śliż K Tags: Pneumonol Alergol Pol Source Type: research

Clara Cell protein and myeloperoxidase levels in serum of subjects after exposure to fire smoke.
Conclusions. As indicated, acute exposure to smoke induces injury at the alveolar level, which results in a transient increase of CC16 in serum of exposed subjects. PMID: 23258467 [PubMed - in process] (Source: Pneumonologia i Alergologia Polska)
Source: Pneumonologia i Alergologia Polska - January 17, 2013 Category: Respiratory Medicine Authors: Krakowiak A, Hałatek T, Nowakowska-Świrta E, Winnicka R, Politański P, Swiderska-Kiełbik S Tags: Pneumonol Alergol Pol Source Type: research

[Usefulness of NT-proBNP serum level in the diagnosis of dyspnea in COPD patients.]
Conclusions. 1. In the group of stable COPD patients there were no differences between NT-proBNP serum concentration according to GOLD staging, BODE index, and mMRC breathlessness scale. 2. The NT-proBNP serum concentration was statistically significantly higher in the group of COPD patients with the concomitant cardiovascular disease. 3. In patients with chronic dyspnoea testing of serum NT-proBNP may be useful in the detection of patients with cardiovascular problems, who require more intensive therapy. PMID: 23258468 [PubMed - as supplied by publisher] (Source: Pneumonologia i Alergologia Polska)
Source: Pneumonologia i Alergologia Polska - January 17, 2013 Category: Respiratory Medicine Authors: Rubinsztajn R, Nasiłowski J, Przybyłowski T, Karwat K, Chazan R Tags: Pneumonol Alergol Pol Source Type: research

[Outcome after PET-CT based radiotherapy for non-small cell lung cancer.]
Conclusions. The high early mortality rate in the patients disqualified from curative radiotherapy after PET-CT suggests the potential value of PET-CT for improving the radiotherapy outcome. However, this benefit seems to be limited in stage III patients. PMID: 23258469 [PubMed - as supplied by publisher] (Source: Pneumonologia i Alergologia Polska)
Source: Pneumonologia i Alergologia Polska - January 17, 2013 Category: Respiratory Medicine Authors: Socha J, Kołodziejczyk M, Kępka L Tags: Pneumonol Alergol Pol Source Type: research

[Occult bronchial foreign bodies - analysis of own material.]
Conclusion. OBFB is a rare condition, but has to be taken into consideration as a cause of chest radiological pathology and in patients with chronic and/or recurrent inflammatory disease of the respiratory system. PMID: 23258470 [PubMed - as supplied by publisher] (Source: Pneumonologia i Alergologia Polska)
Source: Pneumonologia i Alergologia Polska - January 17, 2013 Category: Respiratory Medicine Authors: Szafrański W, Dobielski J, Papiewski W, Czechowska U Tags: Pneumonol Alergol Pol Source Type: research

[Genetic variants of alpha-1 antitrypsin: classification and clinical implications.]
Abstract Inherited alpha-1 antitrypsin deficiency is listed among the three most common genetic disorders in Caucasians. It considerably increases the risk of progressive obstructive lung diseases, mostly chronic obstructive pulmonary disease, as well as chronic liver disorders, hepatitis, cirrhosis, and cancer. It is estimated that more than 5.5% of the Polish population carries one of the most common deficiency phenotypes, which might be relatively easily detected due to low alpha-1 antitrypsin serum concentration. However, as well as being quantitative, alpha-1 antitrypsin deficiency might also be q...
Source: Pneumonologia i Alergologia Polska - January 17, 2013 Category: Respiratory Medicine Authors: Popławska B, Janciauskiene S, Chorostowska-Wynimko J Tags: Pneumonol Alergol Pol Source Type: research

[Treatment of non-small cell lung cancer - where we are?]
Abstract Lung cancer is the most common cancer in Poland and in the world, unfortunately diagnosed too late, and combined with a very poor prognosis. For most patients with NSCLC the only possibility of treatment is palliative therapy, including chemotherapy and, in the recent years, molecular targeted therapy. In first-line treatment, cisplatine-based "doublets" are most effective, and in second-line, pemetreksed and docetaxel are used. Recently, maintenance chemotherapy has been introduced. Although standard chemotherapy improves the quality of life in the patients with advanced NSCLC, due to signif...
Source: Pneumonologia i Alergologia Polska - January 17, 2013 Category: Respiratory Medicine Authors: Milanowski J, Szmygin-Milanowska K Tags: Pneumonol Alergol Pol Source Type: research

[Pneumocystosis in a patient with lymphangioleiomyomatosis.]
Abstract A 47-year-old, non-smoking woman was admitted to the National Tuberculosis and Lung Diseases Research Institute for diagnosis of progressive exertional dyspnoea and numerous small thin-walled, air-filled cysts equally distributed throughout both lungs revealed in HRCT (high resolution computed tomography) examination. Histological assessment of specimens obtained by open lung biopsy revealed proliferation of immature smooth muscle, showing the expression of the antigen HMB45. On this basis, diagnosis of lymphangioleiomyomatosis was established. The disease caused essential ventilation damage ...
Source: Pneumonologia i Alergologia Polska - January 17, 2013 Category: Respiratory Medicine Authors: Mydłowski T, Radzikowska E, Oniszh K, Szczepulska-Wójcik E, Jaguś P, Wiatr E Tags: Pneumonol Alergol Pol Source Type: research

[Nodular lymphoid hyperplasia - a rare case of lymphoproliferative disorder of the lungs.]
Abstract Nodular lymphoid hyperplasia (NLH) belongs to a very rare, mild, lymphoproliferative disease of unestablished aetiology historically included in the group of pseudolymphomas. Its existence was controversial for many years, until modern techniques of pathomorphological diagnosis approved it as a separate entity of lung disease. It manifests in the form of well limited nodules localized in the lungs, which are mostly identified accidentally. Clinical symptoms are rare and nonspecific; the disease usually occupies only one lung. Pathomorphological diagnosis requires immunohistochemical designatio...
Source: Pneumonologia i Alergologia Polska - January 17, 2013 Category: Respiratory Medicine Authors: Rogoziński P, Bruliński K, Malinowski E, Wandzel P, Kucharzewski M Tags: Pneumonol Alergol Pol Source Type: research