Polymorphism of the ACE gene and the risk of obstructive sleep apnoea.
CONCLUSIONS: Analysis of ACE gene polymorphism might be useful to determine the risk of developing OSA in clinically predisposed patients. PMID: 23609427 [PubMed - in process] (Source: Pneumonologia i Alergologia Polska)
Source: Pneumonologia i Alergologia Polska - May 26, 2013 Category: Respiratory Medicine Authors: Chmielewska I, Mlak R, Krawczyk P, Czukiewska E, Milanowski J Tags: Pneumonol Alergol Pol Source Type: research

Assessment of recurrence of non-small cell lung cancer after therapy using CT and Integrated PET/CT.
CONCLUSIONS: FDG PET-CT was the best method to differentiate recurrent bronchogenic carcinoma from inflammatory lesions, especially at post-therapeutic sites. It has been shown that PET-CT is more accurate method than CT in recurrent NSCLC. PET-CT results had a further impact on the clinical management and treatment planning. PMID: 23609428 [PubMed - in process] (Source: Pneumonologia i Alergologia Polska)
Source: Pneumonologia i Alergologia Polska - May 26, 2013 Category: Respiratory Medicine Authors: Opoka L, Szołkowska M, Podgajny Z, Kunikowska J, Barańska I, Błasińska-Przerwa K, Jakubowska L, Rudziński P, Bestry I, Roszkowski-Śliż K Tags: Pneumonol Alergol Pol Source Type: research

[Sleep related breathing disorders in adults - recommendations of Polish Society of Lung Diseases.]
Abstract Not available. PMID: 23609429 [PubMed - as supplied by publisher] (Source: Pneumonologia i Alergologia Polska)
Source: Pneumonologia i Alergologia Polska - May 26, 2013 Category: Respiratory Medicine Authors: Pływaczewski R, Brzecka A, Bielicki P, Czajkowska-Malinowska M, Cofta S, Jonczak L, Radliński J, Tażbirek M, Wasilewska J Tags: Pneumonol Alergol Pol Source Type: research

[Benefits of oxygen on exercise performance in patients with chronic lung diseases].
Abstract Chronic respiratory diseases limit exercise capacity, due to breathlessness and hypoxemia. A decrease in daily activity results in impairment of quality of life and higher mortality. Oxygen therapy improves exercise capacity. The main mechanism of this improvement in COPD patients is a reduction in dynamic hyperinflation. The benefits of oxygen therapy is present not only in patients with severe hypoxemia at rest (PaO2 < 60 mm Hg) requiring long-term oxygen therapy, but also in mild hypoxemic patients who develop desaturation during exercise. An improvement in exercise tolerance is proportional...
Source: Pneumonologia i Alergologia Polska - May 26, 2013 Category: Respiratory Medicine Authors: Nasiłowski J Tags: Pneumonol Alergol Pol Source Type: research

[Severe hypoxemic respiratory insufficiency in a patient with hepato-pulmonary syndrome coexisting with interstitial lung disease of unknown etiology].
We present a patient with severe hypoxemic respiratory insufficiency in whom hepato-pulmonary syndrome coexisted with interstitial lung disease of unknown etiology. The mechanisms of hypoxemia in the course of hepatic diseases and reasons of possible coincidence of lung and hepatic pathology are discussed. PMID: 23609431 [PubMed - in process] (Source: Pneumonologia i Alergologia Polska)
Source: Pneumonologia i Alergologia Polska - May 26, 2013 Category: Respiratory Medicine Authors: Gorzkowska-Pasik K, Wiatr E, Burakowska B, Nowicka U, Kober J, Malong P, Pasik P, Folcik K Tags: Pneumonol Alergol Pol Source Type: research

[Fibrosing mediastinitis with pulmonary hypertension as a rare complication of sarcoidosis].
We present a case of 42-year-old woman with sarcoidosis, who had developed fibrosing mediastinitis and pulmonary hypertension. Contrast-enhanced computer tomography showed abnormal, bilateral, solid tissues surrounding the hila and mediastinum. Magnetic resonance imaging showed: abnormal, intermediate signal tissue in the mediastinum, surrounding hila, narrowing both lower lobe arteries and both lobe bronchi, left upper lobe atelectasis, and contrast enhancement of mediastinal infiltration. The patient was treated with steroids for 14 months (initial dose of prednisone was 1 mg/kg/day, then tapered) with clinical and radio...
Source: Pneumonologia i Alergologia Polska - May 26, 2013 Category: Respiratory Medicine Authors: Załęska M, Błasińska-Przerwa K, Oniszh K, Roszkowska-Śliż B, Roszkowski-Śliż K Tags: Pneumonol Alergol Pol Source Type: research

[MD Jerzy Włodzimierz Góralczyk (1934-2012) - obituary].
PMID: 23609433 [PubMed - in process] (Source: Pneumonologia i Alergologia Polska)
Source: Pneumonologia i Alergologia Polska - May 26, 2013 Category: Respiratory Medicine Authors: Janczy J, Zieliński M Tags: Pneumonol Alergol Pol Source Type: research

Legal aspects of tuberculosis diagnostics and treatment.
PMID: 23420423 [PubMed - in process] (Source: Pneumonologia i Alergologia Polska)
Source: Pneumonologia i Alergologia Polska - February 22, 2013 Category: Respiratory Medicine Authors: Zielonka TM Tags: Pneumonol Alergol Pol Source Type: research

Cardiac tamponade - diagnostic and therapeutic considerations.
PMID: 23420424 [PubMed - in process] (Source: Pneumonologia i Alergologia Polska)
Source: Pneumonologia i Alergologia Polska - February 22, 2013 Category: Respiratory Medicine Authors: Szturmowicz M Tags: Pneumonol Alergol Pol Source Type: research

Administration of conestat alfa, human C1 esterase inhibitor and icatibant in the treatment of acute angioedema attacks in adults with hereditary angioedema due to C1 esterase inhibitor deficiency. Treatment comparison based on systematic review results.
Conclusions: Due to significant heterogeneity of identified trials, the scientific evidence available was insufficient to point out the most effective therapeutic option in the treatment of acute oedemas in HAE. PMID: 23420425 [PubMed - in process] (Source: Pneumonologia i Alergologia Polska)
Source: Pneumonologia i Alergologia Polska - February 22, 2013 Category: Respiratory Medicine Authors: Kawalec P, Holko P, Paszulewicz A, Obtułowicz K Tags: Pneumonol Alergol Pol Source Type: research

Analysis of the frequency of isolation and drug resistance of microorganisms isolated from the airways of adult CF patients treated in the Institute of Tuberculosis and Lung Disease during 2008-2011.
Conclusions: The analysis of microbiological materials from adult CF patients treated in IGiChP allowed the determination of the prevalence of potentially pathogenic microorganisms. The data obtained are consistent with the literature. PMID: 23420426 [PubMed - in process] (Source: Pneumonologia i Alergologia Polska)
Source: Pneumonologia i Alergologia Polska - February 22, 2013 Category: Respiratory Medicine Authors: Iwańska A, Nowak J, Skorupa W, Augustynowicz-Kopeć E Tags: Pneumonol Alergol Pol Source Type: research

[The long-term variability of FeNO in pregnant asthmatic women with controlled asthma.]
Conclusions: High long-term variability of fractional exhaled nitric oxide values revealed in pregnant women with well-controlled asthma indicates that changes in this parameter should be interpreted with caution while being used for asthma treatment monitoring. PMID: 23420427 [PubMed - as supplied by publisher] (Source: Pneumonologia i Alergologia Polska)
Source: Pneumonologia i Alergologia Polska - February 22, 2013 Category: Respiratory Medicine Authors: Dor-Wojnarowska A, Nittner-Marszalska M, Liebhart J, Marszalska H, Pawłowicz R, Gillert M, Kazimierczak A, -Filarska MK, Panaszek B Tags: Pneumonol Alergol Pol Source Type: research

Extrapulmonary tuberculosis in Poland in the years 1974-2010.
Conclusions: The proportion of EPTB to all cases of TB is lower in Poland than in other countries. In addition, the proportion of EPTB had significantly decreased from 1974-1982 to 2002-2010. It may be due to difficulties in diagnosis of those forms of TB in Poland. Alternatively it is possible that those cases diagnosed in non-respiratory centres are not reported to the National TB Register. PMID: 23420428 [PubMed - in process] (Source: Pneumonologia i Alergologia Polska)
Source: Pneumonologia i Alergologia Polska - February 22, 2013 Category: Respiratory Medicine Authors: Rowińska-Zakrzewska E, Korzeniewska-Koseła M, Roszkowski-Śliż K Tags: Pneumonol Alergol Pol Source Type: research

Restriction of patient's autonomy in diagnosis and treatment of tuberculosis.
Abstract The article presents basic legal regulations concerning the restriction of a patients' autonomy (patients who suffer from or are suspected of tuberculosis). Furthermore, the main responsibilities of a doctor suspecting or diagnosing a disease have been shown, including the issue of using direct coercion towards patients evading compulsory treatment and other legally defined obligations. The article also presents changes made by the newest alteration of law on the prevention and fight against infections and septic diseases. PMID: 23420429 [PubMed - in process] (Source: Pneumonologia i Alergologia Polska)
Source: Pneumonologia i Alergologia Polska - February 22, 2013 Category: Respiratory Medicine Authors: Augustynowicz A, Wrześniewska-Wal I Tags: Pneumonol Alergol Pol Source Type: research

The biological role of prokaryotic and eukaryotic N-acetyltransferase.
Abstract The N-acetyltransferases (NAT; E.C.2.3.1.5) are involved in the metabolism of drugs and environmental toxins. They catalyse the acetyl transfer from acetyl coenzyme A to an aromatic amine, heterocyclic amine, or hydrazine compound. NAT homologues are present in numerous species from bacteria to human. Sequence variations in the human NAT1 and NAT2 result in the production of NAT proteins with variable enzyme activity or stability, leading to slow or rapid acetylation. Therefore, genetic polymorphisms in NAT1 and NAT2 influence drug metabolism and drug-related toxicity. Epidemiological studies ...
Source: Pneumonologia i Alergologia Polska - February 22, 2013 Category: Respiratory Medicine Authors: Zabost A, Zwolska Z, Augustynowicz-Kopeć E Tags: Pneumonol Alergol Pol Source Type: research