Prospects for vaccination against pathogenic African trypanosomes
This article is protected by copyright. All rights reserved. (Source: Parasite Immunology)
Source: Parasite Immunology - September 15, 2016 Category: Parasitology Authors: Samuel J Black, John M. Mansfield Tags: Commissioned Review or Article Source Type: research
Surface proteins of Setaria cervi induces inflammation in macrophage through Toll ‐ like Receptor 4 (TLR4) mediated signaling pathway
This article is protected by copyright. All rights reserved. (Source: Parasite Immunology)
Source: Parasite Immunology - August 31, 2016 Category: Parasitology Authors: Suprabhat Mukherjee, Sandip Mukherjee, Samir Bhattacharya, Santi Prasad Sinha Babu Tags: Original Paper Source Type: research
Immunoprotective effect of lentinan in combination with miltefosine on Leishmania ‐infected J‐774A.1 macrophages
Summary
Rejuvenation of deteriorated host immune functions is imperative for successful annihilation of Leishmania parasites. The use of immunomodulatory agents may have several advantages as they conquer immunosuppression and, when given in combination, improve current therapeutic regimens. We herein investigated the immunostimulatory potency of a β‐glucan, lentinan either alone or in combination with short dose of standard drug, miltefosine on Leishmania‐infected J‐774A.1 macrophages. Our study shows that infected macrophages when stimulated with 2.5 μg/mL and above concentrations of lentinan secreted significan...
Source: Parasite Immunology - August 23, 2016 Category: Parasitology Authors: R. Shivahare, W. Ali, U. S. Singh, S. M. Natu, S. Khattri, S. K. Puri, S. Gupta Tags: Original Paper Source Type: research
Host Th1/Th2 immune response to Taenia solium cyst antigens in relation to cyst burden of neurocysticercosis
This study examined ex vivo CD4+ T cells and in vitro Th1 and Th2 cytokine responses to T solium cyst antigens of peripheral blood mononuclear cells of healthy subjects from endemic and non‐endemic regions and of single and multi‐cyst infected patients for association to cyst burden of neurocysticercosis.
T solium cyst antigens elicited a Th1 cytokine response in healthy subjects of T solium endemic and non‐endemic regions and those with single cyst infections and a Th2 cytokine response from subjects with multi‐cyst neurocysticercosis. Multi‐cyst neurocysticercosis subjects also exhibited low levels of effector ...
Source: Parasite Immunology - August 4, 2016 Category: Parasitology Authors: Jayaraman Tharmalingam, Prabhakar T Appaswamy, Prakash Gangadaran, Pierre Dorny, Jozef Vercruysse, Peter Geldhof, Rajshekhar Vedantam, Mathew Alexander, Anna Oommen Tags: Original Paper Source Type: research
Approaches to vaccination against Theileria parva and Theileria annulata
This article is protected by copyright. All rights reserved. (Source: Parasite Immunology)
Source: Parasite Immunology - July 31, 2016 Category: Parasitology Authors: Vishvanath Nene, W. Ivan Morrison Tags: Commissioned Review or Article Source Type: research
A whole ‐killed, blood‐stage lysate vaccine protects against the malaria liver stage
This article is protected by copyright. All rights reserved. (Source: Parasite Immunology)
Source: Parasite Immunology - July 31, 2016 Category: Parasitology Authors: Xiao Lu, Taiping Liu, Feng Zhu, Lin Chen, Wenyue Xu Tags: Original Paper Source Type: research
A recombinant chimeric protein composed by human and mice ‐specific CD4+ and CD8+ T cell epitopes protects against visceral leishmaniasis
In conclusion, the RCP/saponin vaccine could be considered as a prophylactic alternative to prevent against VL.
This article is protected by copyright. All rights reserved. (Source: Parasite Immunology)
Source: Parasite Immunology - July 31, 2016 Category: Parasitology Authors: V ívian T. Martins, Mariana C. Duarte, Daniela P. Lage, Lourena E. Costa, Ana Maria R. S. Carvalho, Tiago A. O. Mendes, Bruno M. Roatt, Daniel Menezes‐Souza, Manuel Soto, Eduardo A. F. Coelho Tags: Original Paper Source Type: research
Overview of dendritic cell ‐based vaccine development for leishmaniasis
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Source: Parasite Immunology - July 31, 2016 Category: Parasitology Authors: Melahat Bagirova, Adil M. Allahverdiyev, Emrah Sefik Abamor, Ikram Ullah, Gizem Cosar, Mehmet Aydogdu, Hilal Senturk, Bengu Ergenoglu Tags: Review Source Type: research
Induction of regulatory T cells by Opisthorchis viverrini
This study indicated that O. viverrini infected hamsters could induce TGF‐β+ CD4+ Treg‐like cells. The CSAg specific Tregs secreted high TGF‐β, and limited immune cell proliferation.
This article is protected by copyright. All rights reserved. (Source: Parasite Immunology)
Source: Parasite Immunology - July 31, 2016 Category: Parasitology Authors: Chamraj Kaewraemruaen, Rasana W. Sermswan, Surasakdi Wongratanacheewin Tags: Original Paper Source Type: research
Signaling pathways associated with IL ‐6 production and EMT induction in prostate epithelial cells stimulated with Trichomonas vaginalis
This article is protected by copyright. All rights reserved. (Source: Parasite Immunology)
Source: Parasite Immunology - July 31, 2016 Category: Parasitology Authors: Ik ‐Hwan Han, Jung‐Hyun Kim, Sang‐Su. Kim, Myoung Hee Ahn, Jae‐Sook Ryu Tags: Original Paper Source Type: research
Evaluation of a novel lentiviral vaccine expressing KMP11 ‐HASPB fusion protein against Leishmania infantum in BALB/c mice
This article is protected by copyright. All rights reserved. (Source: Parasite Immunology)
Source: Parasite Immunology - July 31, 2016 Category: Parasitology Authors: Nahid Mortazavidehkordi, Akbar Farjadfar, Hossein Khanahmad, Zahra Ghayour Najafabadi, Nooshin Hashemi, Ali Fallah, Ali Najafi, Vahid Kia, Seyed Hossein Hejazi Tags: Original Paper Source Type: research
Editorial – One Health Special Issue – Parasite Immunology
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Source: Parasite Immunology - July 31, 2016 Category: Parasitology Authors: Grace Mulcahy Tags: Commissioned Review or Article Source Type: research
Fusion of foreign T ‐cell epitopes and addition of TLR agonists enhance immunity against Neospora caninum profilin in cattle
This article is protected by copyright. All rights reserved. (Source: Parasite Immunology)
Source: Parasite Immunology - July 31, 2016 Category: Parasitology Authors: Florencia Celeste Mansilla, Mar ía Eugenia Quintana, Nancy Patricia Cardoso, Alejandra Victoria Capozzo Tags: Original Paper Source Type: research
M1 polarization and the effect of PGE2 on TNF ‐α production by lymph node cells from dogs with visceral leishmaniasis
This study aimed to evaluate the arginase activity in adherent macrophages cultured from the lymph nodes of healthy and naturally infected dogs and to examine the NO2 and PGE2 levels in the supernatant of these cultures. In addition, the regulatory effect of PGE2 on the production of tumor necrosis factor (TNF‐α) and interleukin‐10 (IL‐10) in supernatants from the total lymph node were observed in leukocyte cultures. The arginase activity was lower in the adherent macrophages cultured from the lymph nodes of naturally infected dogs and there were higher concentrations of NO2 and PGE2 in the supernatants of these cul...
Source: Parasite Immunology - July 31, 2016 Category: Parasitology Authors: Gabriela Lovizutto Venturin, Vanessa Marim Chiku, Kathlenn Liezbeth Oliveira Silva, Breno Fernando Martins de Almeida, Val éria Marçal Felix de Lima Tags: Brief Definitive Report Source Type: research
Rice ‐produced MSP142 of Plasmodium falciparum elicits antibodies that inhibit parasite growth in vitro
This article is protected by copyright. All rights reserved. (Source: Parasite Immunology)
Source: Parasite Immunology - July 31, 2016 Category: Parasitology Authors: Qin Chen, Wanqi. Liang, Feng. Qian, Bingjun Qian, Jianping Cao, Dabing Zhang, Yuxin Xu, Linhua Tang Tags: Original Paper Source Type: research
