Cover Image
Cover Illustration: The image illustrates the massive influx of effector cells around the larvae during a protective secondary infection with N. brasiliensis. Eosinophils and macrophages (that are positive for F4/80 in the lung) are recruited and activated by the cytokines made by ILC2s during a helminth infection. (Source: Parasite Immunology)
Source: Parasite Immunology - January 29, 2018 Category: Parasitology Tags: COVER IMAGE Source Type: research

Intestinal parasites: Associations with intestinal and systemic inflammation
Parasite Immunology,Volume 40, Issue 4, April 2018. (Source: Parasite Immunology)
Source: Parasite Immunology - January 24, 2018 Category: Parasitology Source Type: research

A sticky end for gastrointestinal helminths; the role of the mucus barrier
Parasite Immunology,Volume 40, Issue 4, April 2018. (Source: Parasite Immunology)
Source: Parasite Immunology - January 22, 2018 Category: Parasitology Source Type: research

Dihydrotestosterone enhances growth and infectivity of Leishmania  Mexicana
Summary A strong sex‐associated susceptibility towards Leishmania has been reported in males, yet little is known on the effect of hormones in Leishmania physiopathogenicity. Due to the enhanced susceptibility of males to Leishmania mexicana infections, we were interested in analysing the effect exerted by the main androgen produced in males (DHT) on L. mexicana promastigotes. Thus, the aim of this study was to assess the regulation exerted by dihydrotestosterone (DHT) on L. mexicana replication, infectivity, survival and development of tissue lesions. Experiments included growth curves of L. mexicana promastigotes incu...
Source: Parasite Immunology - January 18, 2018 Category: Parasitology Authors: L. S ánchez‐García, A. Wilkins‐Rodriguez, N. Salaiza‐Suazo, J. Morales‐Montor, I. Becker Tags: ORIGINAL ARTICLE Source Type: research

Humoral and T cell –mediated immune response against trichomoniasis
Summary Trichomonas vaginalis (T. vaginalis) infection leads to the synthesis of specific antibodies in the serum and local secretions. The profile of T. vaginalis‐specific antibodies and T cell–mediated immune responses may influence the outcome of infection, towards parasite elimination, persistence or pathological reactions. Studies have indicated that Th1‐, Th17‐ and Th22 cell‐related cytokines may be protective or pathogenic, whereas Th2‐ and Treg cell‐related cytokines can exert anti‐inflammatory effects during T. vaginalis infection. A number of T. vaginalis‐related components such as lipophosp...
Source: Parasite Immunology - January 11, 2018 Category: Parasitology Authors: M. Nemati, N. Malla, M. Yadav, H. Khorramdelazad, A. Jafarzadeh Tags: REVIEW ARTICLE Source Type: research

Demodex canis targets TLRs to evade host immunity and induce canine demodicosis
Summary Widespread incidence of Demodex mites throughout the mammalian class and occasional serious and fatal outcomes in dogs warrant an insight into the host‐parasite interface especially. Therefore, this study was aimed to unravel the interplay between innate immune response and canine demodicosis. The dogs diagnosed to have natural clinical demodicosis were allocated into two groups; dogs with localized demodicosis (LD) and with generalized demodicosis (GD). The expression of toll‐like receptors (TLRs) 2, 4 and 6 genes in peripheral blood mononuclear cells of these dogs was quantified by real‐time PCR. Significan...
Source: Parasite Immunology - January 7, 2018 Category: Parasitology Authors: P. Kumari, R. Nigam, S. Choudhury, S. K. Singh, B. Yadav, D. Kumar, S. K. Garg Tags: BRIEF DEFINITIVE REPORT Source Type: research

Evaluation of T cell responses in healing and nonhealing leishmaniasis reveals differences in T helper cell polarisation ex vivo and in vitro
Parasite Immunology,Volume 0, Issue ja, -Not available-. (Source: Parasite Immunology)
Source: Parasite Immunology - January 6, 2018 Category: Parasitology Authors: Beak ‐San Choi , Pascale Kropf* Source Type: research

Local immune response to larvae of Rhipicephalus microplus in Santa Gertrudis cattle
Parasite Immunology,Volume 40, Issue 4, April 2018. (Source: Parasite Immunology)
Source: Parasite Immunology - January 4, 2018 Category: Parasitology Source Type: research

Intestinal parasites: associations with intestinal and systemic inflammation
ConclusionIntestinal parasitic infection was not associated with systemic inflammation, but was associated with intestinal inflammation. Having multiple‐infections were associated with higher leptin concentrations.This article is protected by copyright. All rights reserved. (Source: Parasite Immunology)
Source: Parasite Immunology - January 1, 2018 Category: Parasitology Authors: Gerardo A Zavala, Olga P Garc ía, Mariela Camacho, Dolores Ronquillo, Maiza Campos‐Ponce, Colleen Doak, Katja Polman, Jorge L Rosado Tags: Original Article Source Type: research

A sticky end for gastrointestinal helminths; the role of the mucus barrier
This article is protected by copyright. All rights reserved. (Source: Parasite Immunology)
Source: Parasite Immunology - January 1, 2018 Category: Parasitology Authors: Catherine Sharpe, David J. Thornton, Richard K. Grencis Tags: Review Source Type: research

Group 1 innate lymphoid cells in Toxoplasma gondii infection
This article is protected by copyright. All rights reserved. (Source: Parasite Immunology)
Source: Parasite Immunology - January 1, 2018 Category: Parasitology Authors: Ildiko Rita Dunay, Andreas Diefenbach Tags: Commissioned Review or Article Source Type: research

Local immune response to larvae of  Rhipicephalus microplus in Santa Gertrudis cattle Immune response against Rhipicephalus microplus
ConclusionOur data suggest that some of the cellular responses mounted at larval attachment site are not involved in tick protection. The mAbs specific for CD45 and CD45 RO directly, or a test for CD45 genotype might be developed as markers of tick susceptibility or resistance.This article is protected by copyright. All rights reserved. (Source: Parasite Immunology)
Source: Parasite Immunology - January 1, 2018 Category: Parasitology Authors: Constantin Constantinoiu, Ala Lew ‐Tabor, Louise Jackson, Wayne Jorgensen, Emily Piper, David Mayer, Linda Johnson, Bronwyn Venus, Nicholas Jonsson Tags: Original Paper Source Type: research

Preclinical efficacy and immunogenicity assessment to show that a chimeric Plasmodium falciparum UB05 ‐09 antigen could be a Malaria Vaccine Candidate
ConclusionThese data suggest that UB05‐09 is a malaria vaccine candidate that could be developed further and used in conjunction with AMA1 to create a potent malaria vaccine.This article is protected by copyright. All rights reserved. (Source: Parasite Immunology)
Source: Parasite Immunology - December 29, 2017 Category: Parasitology Authors: |Jerome Nyhalah Dinga, Dobgima Stanley Gamua, Stephen Mbigha Ghogomu, Vincent P. K. Titanji Tags: Original Paper Source Type: research

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Parasite Immunology,Volume 40, Issue 3, March 2018. (Source: Parasite Immunology)
Source: Parasite Immunology - December 28, 2017 Category: Parasitology Source Type: research

Innate lymphoid cells and parasites: ancient foes with shared history
This article is protected by copyright. All rights reserved. (Source: Parasite Immunology)
Source: Parasite Immunology - December 26, 2017 Category: Parasitology Authors: Daniel R Neill, Padraic G Fallon Tags: Commissioned Review or Article Source Type: research