Antibody and cytokine levels in humans fed on by the common bedbug, Cimex lectularius L
Summary
Little is known about cimicosis, the resultant dermal reaction from feeding activity by the common bedbug, Cimex lectularius L. We fed C. lectularius on human study subjects four times over four weeks and measured serum cytokine and antibody levels, and subjects recorded any cimicosis. The average time for subjects to develop cimicosis decreased with each feeding from 8.4, to 2.1, 1.5 and 1.3 days, respectively. There were no significant changes in total IgG, IgG1, IgG2, IgG4 or IgE levels between the first and fourth bedbug feedings, but there was a significant decrease in total IgG3 levels (P<.001). IgG4 was ...
Source: Parasite Immunology - March 15, 2017 Category: Parasitology Authors: J. M. Sheele, G. E. Ridge, K. Coppolino, T. Bonfield, A. B. Young, S. L. Gaines, T. S. McCormick Tags: ORIGINAL ARTICLE Source Type: research
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(Source: Parasite Immunology)
Source: Parasite Immunology - March 15, 2017 Category: Parasitology Tags: Issue Information Source Type: research
The role of microRNAs in Anopheles biology —an emerging research field
Summary
In the last years, microRNAs (miRNAs) have been established as important post‐transcriptional regulators of critical physiological processes in animals and plants. Here, we summarize what is known about miRNA biosynthesis, expression and function in the malaria vector mosquito Anopheles gambiae with a particular emphasis on the mosquito‐parasite interactions. We discuss the important gaps in the current knowledge, including the potential of miRNA manipulation for future vector control strategies. (Source: Parasite Immunology)
Source: Parasite Immunology - March 14, 2017 Category: Parasitology Authors: L. Lampe, E. A. Levashina Tags: COMMISSIONED REVIEW ARTICLE Source Type: research
microRNAs —key players in host–parasite interactions
(Source: Parasite Immunology)
Source: Parasite Immunology - March 14, 2017 Category: Parasitology Authors: C. Britton Tags: EDITORIAL Source Type: research
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(Source: Parasite Immunology)
Source: Parasite Immunology - March 14, 2017 Category: Parasitology Tags: Issue Information Source Type: research
AIM2 inflammasome is associated to disease severity in tegumentary leishmaniasis caused by Leishmania (V.) braziliensis
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Source: Parasite Immunology - March 1, 2017 Category: Parasitology Authors: Regina Barbosa Moreira, Claude Pirmez, Manoel Paes De Oliveira ‐Neto, Luana De Souza Aguiar, Antonio José Da Silva Gonçalves, Luiza Oliveira Ramos Pereira, Lais Abreu, Márcia Pereira De Oliveira Tags: Original Article Source Type: research
Evidence of cross ‐stage CD8+ T cell epitopes in malaria pre‐erythrocytic and blood stage infections
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Source: Parasite Immunology - March 1, 2017 Category: Parasitology Authors: Katja M üller, Matthew Paul Gibbins, Kai Matuschewski, Julius Clemence Hafalla Tags: Brief Definitive Report Source Type: research
EDITORIAL ‐ Parasites and Metabolic diseases
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Source: Parasite Immunology - March 1, 2017 Category: Parasitology Authors: Bruno Guigas Tags: Commissioned Review or Article Source Type: research
The effect of three ‐monthly albendazole treatment on Th2 responses: Differential effects on IgE and IL‐5
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Source: Parasite Immunology - March 1, 2017 Category: Parasitology Authors: Karin de Ruiter, Dicky L. Tahapary, Linda Wammes, Aprilianto E. Wiria, Firdaus Hamid, Lisette van Lieshout, Johannes W.A. Smit, Jeanine J. Houwing ‐Duistermaat, Erliyani Sartono, Taniawati Supali, Maria Yazdanbakhsh Tags: Brief Definitive Report Source Type: research
Cytokine and antioxidant gene profiles from peripheral blood mononuclear cells of Pelibuey lambs after Haemonchus contortus infection
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Source: Parasite Immunology - March 1, 2017 Category: Parasitology Authors: Zaira Estrada ‐Reyes, Ma. Eugenia López‐Arellano, Felipe Torres‐Acosta, Alberto López‐Reyes, Alfredo Lagunas‐Martínez, Pedro Mendoza‐de‐Gives, Roberto González‐Garduño, Sara Olazarán‐Jenkins, David Reyes‐Guerrero, Gabriel Ramíre Tags: Brief Definitive Report Source Type: research
American cutaneous leishmaniasis: In situ immune response of patients with recent and late lesions
In conclusion, these data suggested that: i. patients from Group I had recent lesions (in the beginning of chronic phase) compared to those from Group II; ii. the modulation of inflammatory response in patients with recent ACL was correlated with IL‐10 expression in skin lesions preventing the development of mucosal forms. The parasite treatment also prevented the evolution of severe forms.
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Source: Parasite Immunology - February 25, 2017 Category: Parasitology Authors: Aparecida Helena Souza Gomes, Roosecelis Brasil Martines, Cristina Takami Kanamura, Maria Lourdes Peris Barbo, Silvia D'Andretta Iglezias, Jos é Angelo Lauletta Lindoso, Vera Lucia Pereira‐Chioccola Tags: Original Paper Source Type: research
In situ immunopathological changes in cutaneous leishmaniasis due to Leishmania donovani
ConclusionA prominent Th1 response appears to support resolving of lesions, whereas a Th2 biased milieu tends to favor poor responsiveness to antimony and delayed lesion healing in L. donovani infections in Sri Lanka.This article is protected by copyright. All rights reserved. (Source: Parasite Immunology)
Source: Parasite Immunology - January 22, 2017 Category: Parasitology Authors: Nuwani H Manamperi, Steve Oghumu, Nishantha Pathirana, Vipula C de Silva, Wimaladharma Abeyewickreme, Abhay R Satoskar, Nadira D Karunaweera Tags: Original Paper Source Type: research
Surface proteins of Setaria cervi induce inflammation in macrophage through Toll ‐like receptor 4 (TLR4)‐mediated signalling pathway
Summary
Lymphatic filariasis is a vectorborne parasitic disease that results in morbidities, disabilities and socio‐economic loss each year globally. Inflammatory consequences associated with any form of filariasis have drawn special attention. However, the molecular insight behind the inflammation of host macrophage (MФ) is considered as one of the shaded areas in filarial research. Herein, major emphasis was given to study the signalling pathway of MФ inflammation induced by surface proteins (SPs) of filarial parasite through in vitro and in vivo approaches. Twenty‐four hours of in vitro stimulation of Raw MФs wit...
Source: Parasite Immunology - January 18, 2017 Category: Parasitology Authors: Su. Mukherjee, Sa. Mukherjee, S. Bhattacharya, S. P. Sinha Babu Tags: ORIGINAL ARTICLE Source Type: research
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(Source: Parasite Immunology)
Source: Parasite Immunology - January 18, 2017 Category: Parasitology Tags: Issue Information Source Type: research
A recombinant cystatin from Ascaris lumbricoides attenuates inflammation of DSS ‐induced colitis
In conclusion, rAl‐CPI reduces inflammation in a mouse model of DSS‐induced colitis, probably by increasing the expression of anti‐inflammatory cytokines and reducing pro‐inflammatory ones.
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Source: Parasite Immunology - December 31, 2016 Category: Parasitology Authors: Sandra Coronado, Luis Barrios, Josefina Zakzuk, Ronald Regino, Velky Ahumada, Luis Franco, Yanet Ocampo, Luis Caraballo Tags: Original Article Source Type: research
