Protective efficacy of recombinant Cryptosporidium parvum CpPRP1 sushi domain against C. tyzzeri infection in mice
This article is protected by copyright. All rights reserved. (Source: Parasite Immunology)
Source: Parasite Immunology - June 1, 2017 Category: Parasitology Authors: Y. Huang, W. Cao, K. Shi, R. Mi, K. Lu, X. Han, Z. Chen Tags: Original Paper Source Type: research
Resiniferatoxin modulates the Th1 immune response and protects the host during intestinal nematode infection
This article is protected by copyright. All rights reserved. (Source: Parasite Immunology)
Source: Parasite Immunology - June 1, 2017 Category: Parasitology Authors: J.L. Mu ñoz‐Carrillo, J. F. Contreras‐Cordero, J.L. Muñoz‐López, C.H. Maldonado‐Tapia, J. J. Muñoz‐Escobedo, M.A. Moreno‐García Tags: Original Article Source Type: research
AIM2 inflammasome is associated with disease severity in tegumentary leishmaniasis caused by Leishmania (V.) braziliensis
Summary
The inflammasome is a multiprotein signalling platform involved in the pathogenesis of various inflammatory skin diseases. Herein, we investigated gene and protein expression of the inflammasome molecules AIM2 and NLRP3 in active lesions from patients with L. (V.) braziliensis‐associated tegumentary leishmaniasis (TL) and correlated these findings with the clinical presentations and responses to therapy. Real‐time PCR assays showed a significantly higher AIM2 gene expression in mucosal leishmaniasis (ML) compared with that in cutaneous leishmaniasis (CL). Additionally, AIM2 mRNA expression was significantly h...
Source: Parasite Immunology - May 29, 2017 Category: Parasitology Authors: R. B. Moreira, C. Pirmez, M. P. Oliveira ‐Neto, L. S. Aguiar, A. J. S. Gonçalves, L. O. R. Pereira, L. Abreu, M. P. De Oliveira Tags: ORIGINAL ARTICLE Source Type: research
Elevated cerebrospinal fluid tumour necrosis factor is associated with acute and long ‐term neurocognitive impairment in cerebral malaria
Summary
Systemic tumour necrosis factor‐α (TNF‐α) may contribute to the pathogenesis of cerebral malaria (CM) by promoting endothelial activation and parasite sequestration. However, less is known about the role of central nervous system (CNS) TNF‐α in CM. We assessed plasma (n=249) and cerebrospinal fluid (CSF) (n=167) TNF‐α levels in Ugandan children with CM, plasma TNF‐α in Ugandan community control children (n=198) and CSF TNF‐α in North American control children who had recovered from leukaemia (n=13). Plasma and CSF TNF‐α were measured by magnetic bead assay. We compared plasma and CSF TNF‐α l...
Source: Parasite Immunology - May 28, 2017 Category: Parasitology Authors: E. Shabani, B. J. Ouma, R. Idro, P. Bangirana, R. O. Opoka, G. S. Park, A. L. Conroy, C. C. John Tags: ORIGINAL ARTICLE Source Type: research
Immunoglobulin M antibodies are not specific for serodiagnosis of human toxocariasis
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Source: Parasite Immunology - May 25, 2017 Category: Parasitology Authors: William Henry Rold án, Guita Rubinsky Elefant, Antonio Walter Ferreira Tags: Original Paper Source Type: research
Synergic and antagonistic relationship between MMP ‐2 and MMP‐9 with fibrosis and inflammation in Chagas’ cardiomyopathy
This article is protected by copyright. All rights reserved. (Source: Parasite Immunology)
Source: Parasite Immunology - May 24, 2017 Category: Parasitology Authors: Nayara I. Medeiros, Juliana A. S. Gomes, Rodrigo Correa ‐Oliveira Tags: Review Source Type: research
Enhanced acquired antibodies to a chimeric Plasmodium falciparum antigen; UB05 ‐09 is associated with protective immunity against malaria
This article is protected by copyright. All rights reserved. (Source: Parasite Immunology)
Source: Parasite Immunology - May 24, 2017 Category: Parasitology Authors: Dinga Jerome Nyhalah, Gamua Stanley Dobgima, Vincent PrydeKehdingha Titanji Tags: Original Paper Source Type: research
Oral contraceptive pills: risky or protective in case of Trichinella spiralis infection?
ConclusionsOestrogen containing pills established a favorable intestinal environment for Trichinella by enhancing Foxp+Treg. cells and stabilizing C‐kit+mast cells, while POPs gave a potential protection with less gravidity, larval burden and eosinophilic infiltrate.This article is protected by copyright. All rights reserved. (Source: Parasite Immunology)
Source: Parasite Immunology - May 19, 2017 Category: Parasitology Authors: Marwa A. Hasby Saad, Dina A. Radi, Eiman A. Hasby Tags: Original Paper Source Type: research
Lipid bodies accumulation in Leishmania infantum ‐infected C57BL/6 macrophages
This article is protected by copyright. All rights reserved. (Source: Parasite Immunology)
Source: Parasite Immunology - May 18, 2017 Category: Parasitology Authors: Nilda E. Rodr íguez, Ryan D. Lockard, Elizabeth A. Turcotte, Théo Araujo‐Santos, Patrícia T. Bozza, Valéria M. Borges, Mary E. Wilson Tags: Brief Definitive Report Source Type: research
Human innate lymphoid cells (ILCs) in filarial infections
This article is protected by copyright. All rights reserved. (Source: Parasite Immunology)
Source: Parasite Immunology - May 15, 2017 Category: Parasitology Authors: Sandra Bonne ‐Année, Thomas B. Nutman Tags: Commissioned Review or Article Source Type: research
Neutrophil alterations in pregnancy ‐associated malaria and induction of neutrophil chemotaxis by Plasmodium falciparum
Summary
Pregnancy‐associated malaria (PAM) is a severe form of the disease caused by sequestration of Plasmodium falciparum‐infected red blood cells (iRBCs) in the developing placenta. Pathogenesis of PAM is partially based on immunopathology, with frequent monocyte infiltration into the placenta. Neutrophils are abundant blood cells that are essential for immune defence but may also cause inflammatory pathology. Their role in PAM remains unclear. We analysed neutrophil alterations in the context of PAM to better understand their contribution to disease development. Pregnant women exposed to Plasmodium falciparum had d...
Source: Parasite Immunology - May 15, 2017 Category: Parasitology Authors: S. Bostr öm, C. Schmiegelow, U. Abu Abed, D. T. R. Minja, J. Lusingu, V. Brinkmann, Y. J. Honkpehedji, M. M. Loembe, A. A. Adegnika, B. Mordmüller, M. Troye‐Blomberg, B. Amulic Tags: BRIEF DEFINITIVE REPORT Source Type: research
Issue Information
(Source: Parasite Immunology)
Source: Parasite Immunology - May 15, 2017 Category: Parasitology Tags: ISSUE INFORMATION Source Type: research
IgE sensitization to Anisakis pegreffii in Italy: comparison of two methods for the diagnosis of allergic anisakiasis
This article is protected by copyright. All rights reserved. (Source: Parasite Immunology)
Source: Parasite Immunology - May 5, 2017 Category: Parasitology Authors: S. Mattiucci, A. Colantoni, B. Crisafi, F. Mori ‐Ubaldini, L. Caponi, P. Fazii, G. Nascetti, F. Bruschi Tags: Original Paper Source Type: research
Trichomonas vaginalis exosome ‐like vesicles modify the cytokine profile and reduce inflammation in parasite‐infected mice
Summary
Trichomonas vaginalis (Tv) is a flagellated parasite commonly spread through sexual transmission. This protozoan initiates a severe inflammatory process, inducing nitric oxide, interleukin‐6 (IL‐6), IL‐8, IL‐10, IL‐17 and IL‐22 production by host immune cells. The parasites elicit these responses by releasing surface lipophosphoglycan, small extracellular vesicles (exosomes) and other factors. Tv exosomes are similar to mammalian exosomes and have been implicated in the modulation of IL‐8 secretion by epithelial cells. Here, we report that exosome‐like vesicles from T. vaginalis (Tv‐ELVs) induced...
Source: Parasite Immunology - May 4, 2017 Category: Parasitology Authors: L. M. Olmos ‐Ortiz, M. A. Barajas‐Mendiola, M. Barrios‐Rodiles, L. E. Castellano, S. Arias‐Negrete, E. E. Avila, P. Cuéllar‐Mata Tags: ORIGINAL ARTICLE Source Type: research
Antecedent Nippostrongylus infection alters the lung immune response to Plasmodium berghei
This article is protected by copyright. All rights reserved. (Source: Parasite Immunology)
Source: Parasite Immunology - May 1, 2017 Category: Parasitology Authors: J M Craig, A L Scott Tags: Original Paper Source Type: research
