Effect of Neutral-pH, Low–Glucose Degradation Product Peritoneal Dialysis Solutions on Residual Renal Function, Urine Volume, and Ultrafiltration: A Systematic Review and Meta-Analysis
This meta-analysis of eleven trials of 643 patients used a random effects model to evaluate the effect of peritoneal dialysate with neutral-pH, low-glucose degradation products on residual renalfunction, urine volume, peritoneal ultrafiltration, and peritoneal small-solute transport (dialysate to plasma creatinine ratio). The results show a positive effect on preservation of residual renal function and greater urine volumes only. However, the authors rightly conclude more studies are needed to determine the effect of these more costly solutions on harder clinical outcomes.
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Effect of Low Versus High Dialy...
Source: Nephrology Now - September 21, 2015 Category: Urology & Nephrology Authors: Nephrology Now editors Tags: Clinical Nephrology Peritoneal Dialysis Residual Renal Function Source Type: research
A nephrology guide to reading and using systematic reviews of observational studies
This review may help the discerning reader to better understand how to critically interpret systemic review of observational studies.
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A nephrology guide to reading and using systematic reviews of randomized trials
Protein electrophoresis and immunofixation for the diagnosis of monoclonal gammopathies
Association of hydroxyethyl starch administration with mortality and acute kidney injury in critically ill patients requiring volume resuscitation: a systematic review and meta-analysis. (Source: Nephrology Now)
Source: Nephrology Now - September 21, 2015 Category: Urology & Nephrology Authors: Nephrology Now editors Tags: Clinical Nephrology Source Type: research
An Incident Cohort Study Comparing Survival on Home Hemodialysis and Peritoneal Dialysis (Australia and New Zealand Dialysis and Transplantation Registry)
This Australia and New Zealand Dialysis and Transplantation Registry database study compared patient and technique survival between patients on home hemodialysis with those on peritoneal dialysis. Overall, on every level that was assessed home hemodialysis was associated with better outcomes than peritoneal dialysis, including 5 year survival (85% vs 44%, respectively; log-rank P<0.001). Patients eligible for both modalities may benefit from this important information.
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Impact of Dialysis Modality on Survival after Kidney Transplant Failure
Propensity-Matched Mortality Comparison of Incident Hemodialysis an...
Source: Nephrology Now - September 21, 2015 Category: Urology & Nephrology Authors: Nephrology Now editors Tags: Clinical Nephrology Clinical Trial Results Hemodialysis Peritoneal Dialysis Source Type: research
Randomized Trial of Bicarbonate or Saline Study for the Prevention of Contrast-Induced Nephropathy in Patients with CKD
Sodium bicarbonate vs sodium chloride has always plagued those of us trying to prevent acute contrast nephropathy. This prospective, double-blind, multicenter randomized clinical trial of 391 with eGFR < 45 ml/min were randomized to either infusion. There was no difference in the primary composite outcome of mortality, dialysis, or a sustained 20% reduction in eGFR at 6 months between the two groups. Furthermore, there was also no difference in the incidence of acute contrast nephropathy between the treatment groups (14.5% versus 12.1%, respectively; P=0.20).
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Acetylcysteine for Prevention of Renal Outcomes i...
Source: Nephrology Now - September 21, 2015 Category: Urology & Nephrology Authors: Nephrology Now editors Tags: Acute Kidney Injury Clinical Nephrology Contrast Nephropathy Source Type: research
Glomerular Diseases Dependent on Complement Activation, Including Atypical Hemolytic Uremic Syndrome, Membranoproliferative Glomerulonephritis, and C3 Glomerulopathy: Core Curriculum 2015
Another great core curriculum that reviews glomerular diseases dependent on complement activation that will benefit both attendings and trainees.
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Genetic Investigations of Kidney Disease
Toxic Nephropathies: Core Curriculum 2010
Tubular Transport: Core Curriculum 2010 (Source: Nephrology Now)
Source: Nephrology Now - September 21, 2015 Category: Urology & Nephrology Authors: Nephrology Now editors Tags: AJKD Core Curriculum Clinical Nephrology Glomerulonephritis Source Type: research
Peri-procedural management of patients taking oral anticoagulants
This article will help guide physician to better provide peri-procedural management of oral anticoagulation therapy.
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Warfarin use, mortality, bleeding and stroke in haemodialysis patients with atrial fibrillation
Update in Nephrology: Evidence Published in 2010
Policy Statement of Canadian Society of Transplantation and Canadian Society of Nephrology on Organ Trafficking and Transplant Tourism (Source: Nephrology Now)
Source: Nephrology Now - September 21, 2015 Category: Urology & Nephrology Authors: Nephrology Now editors Tags: General Nephrology Review Source Type: research
Electrolyte and Acid –Base Disturbances in Patients with Diabetes Mellitus
This review nicely summarizes electrolyte and acid-base base abnormalities and their management in patients with diabetes.
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Integration of Acid–Base and Electrolyte Disorders
Dementia and cognitive impairment in ESRD: diagnostic and therapeutic strategies
Management of patients with acute hyperkalemia (Source: Nephrology Now)
Source: Nephrology Now - September 21, 2015 Category: Urology & Nephrology Authors: Nephrology Now editors Tags: Clinical Nephrology Diabetes Fluid & Electrolytes General Nephrology Source Type: research
Electrolyte and Acid–Base Disturbances in Patients with Diabetes Mellitus
This review nicely summarizes electrolyte and acid-base base abnormalities and their management in patients with diabetes.
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Integration of Acid–Base and Electrolyte Disorders
Dementia and cognitive impairment in ESRD: diagnostic and therapeutic strategies
Management of patients with acute hyperkalemia (Source: Nephrology Now)
Source: Nephrology Now - September 21, 2015 Category: Urology & Nephrology Authors: Nephrology Now editors Tags: Clinical Nephrology Diabetes Fluid & Electrolytes General Nephrology Source Type: research
Transplant Immunology and Immunosuppression: Core Curriculum 2015
This is a nice summary of transplant immunology and immunosuppression.
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General Medical Care of the Dialysis Patient: Core Curriculum 2013.
KDIGO clinical practice guideline for the care of kidney transplant recipients: a summary.
Monoclonal Gammopathy of Undetermined Significance Does Not Affect Outcomes in Patients Undergoing Solid Organ Transplants (Source: Nephrology Now)
Source: Nephrology Now - July 13, 2015 Category: Urology & Nephrology Authors: Nephrology Now editors Tags: AJKD Core Curriculum Source Type: research
Patient Safety Issues in CKD: Core Curriculum 2015
This is a nicely summarize patient safety issues in CKD.
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The effects of lowering LDL cholesterol with simvastatin plus ezetimibe in patients with chronic kidney disease (Study of Heart and Renal Protection): a randomised placebo-controlled trial
General Medical Care of the Dialysis Patient: Core Curriculum 2013.
Acid–Base Problems in Diabetic Ketoacidosis (Source: Nephrology Now)
Source: Nephrology Now - July 13, 2015 Category: Urology & Nephrology Authors: Nephrology Now editors Tags: AJKD Core Curriculum Source Type: research
Current treatment practice and outcomes. Report of the hyponatremia registry
This report from the hyponatremia registry highlights the multifaceted and often clinically disparate approach to the management of hyponatremia. Interestingly, most patients were discharged from hospital still hyponatremic.
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Trends in In-Hospital Cardiopulmonary Resuscitation and Survival in Adults Receiving Maintenance Dialysis
Outcomes of In-Hospital Cardiopulmonary Resuscitation in Maintenance Dialysis Patients
Role of Vaptans in the Management of Hyponatremia (Source: Nephrology Now)
Source: Nephrology Now - July 13, 2015 Category: Urology & Nephrology Authors: Nephrology Now editors Tags: Clinical Nephrology Fluid & Electrolytes General Nephrology Source Type: research
Current treatment practice and outcomes. Report of the hyponatremia registry
This report from the hyponatremia registry highlights the multifaceted and often clinically disparate approach to the management of hyponatremia. Interestingly, most patients were discharged from hospital still hyponatremic.
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Trends in In-Hospital Cardiopulmonary Resuscitation and Survival in Adults Receiving Maintenance Dialysis
Outcomes of In-Hospital Cardiopulmonary Resuscitation in Maintenance Dialysis Patients
Role of Vaptans in the Management of Hyponatremia (Source: Nephrology Now)
Source: Nephrology Now - July 13, 2015 Category: Urology & Nephrology Authors: Nephrology Now editors Tags: Clinical Nephrology Fluid & Electrolytes General Nephrology Source Type: research
A simple clinical tool to inform the decision-making process to refer elderly incident dialysis patients for kidney transplant evaluation
Using data from the French national prospective registry, the authors developed and validated a clinical screening score to identify ESRD patients over the age of 70 years with an acceptable prognosis and hence most suitable for kidney transplantation. This scoring card can be helping to the practicing nephrologist to select suitable patients over the age of 70 years for transplant evaluation.
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Screening and Follow-Up of Living Kidney Donors: A Systematic Review of Clinical Practice Guidelines
Cardiac Survival after Pre-emptive Coronary Angiography in Transplant Patients and Those Await...
Source: Nephrology Now - July 13, 2015 Category: Urology & Nephrology Authors: Nephrology Now editors Tags: Clinical Nephrology Clinical Trial Results Hemodialysis Renal Transplantation Source Type: research
A simple clinical tool to inform the decision-making process to refer elderly incident dialysis patients for kidney transplant evaluation
Using data from the French national prospective registry, the authors developed and validated a clinical screening score to identify ESRD patients over the age of 70 years with an acceptable prognosis and hence most suitable for kidney transplantation. This scoring card can be helping to the practicing nephrologist to select suitable patients over the age of 70 years for transplant evaluation.
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Screening and Follow-Up of Living Kidney Donors: A Systematic Review of Clinical Practice Guidelines
Cardiac Survival after Pre-emptive Coronary Angiography in Transplant Patients and Those Await...
Source: Nephrology Now - July 13, 2015 Category: Urology & Nephrology Authors: Nephrology Now editors Tags: Clinical Nephrology Clinical Trial Results Hemodialysis Renal Transplantation Source Type: research
Long-term medical risks to the living kidney donor
This review nicely summarizes the studies that assess long-term medical outcomes for living kidney donors. Although the focus is on the first 10 years, the authors also note that further studies need to be conducted to better assess risk in certain populations.
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Perioperative Mortality and Long-term Survival Following Live Kidney Donation
Screening and Follow-Up of Living Kidney Donors: A Systematic Review of Clinical Practice Guidelines
Gestational Hypertension and Preeclampsia in Living Kidney Donors (Source: Nephrology Now)
Source: Nephrology Now - July 13, 2015 Category: Urology & Nephrology Authors: Nephrology Now editors Tags: Renal Transplantation Review Source Type: research
