Bone histomorphometry before and after long-term treatment with cinacalcet in dialysis patients with secondary hyperparathyroidism
This long-term follow-up study of dialysis patient treated with cinacalcet for 6-12 months showed improved PTH, biochemical markers as well as bone histology. Of the 77 patients that underwent a second bone biopsy at 12 months, 20 had normal had a normal bone biopsy.
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Long-Term Follow-up of a Randomized Trial Comparing Laparoscopic and Mini-Incision Open Live Donor Nephrectomy
Long-term Renal Outcomes of Patients With Type 1 Diabetes Mellitus and Microalbuminuria
Dialysis-requiring acute renal failure increases the risk of progressive chronic kidney disease (Source: Nephrology Now)
Source: Nephrology Now - May 8, 2015 Category: Urology & Nephrology Authors: Nephrology Now editors Tags: Bone Mineral Metabolism Chronic Kidney Disease Clinical Nephrology Source Type: research
Molecular physiology of water balance
This review describes the recent progress in understanding the roles of selected gene products in the regulation of water balance and their relevance in clinical practice.
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iPhone Nephrology Clinical Calculator
Successful Delivery of RRT in Ebola Virus Disease
Stage IV Chronic Kidney Disease (Source: Nephrology Now)
Source: Nephrology Now - May 8, 2015 Category: Urology & Nephrology Authors: Nephrology Now editors Tags: Clinical Nephrology Fluid & Electrolytes General Nephrology Source Type: research
Molecular physiology of water balance
This review describes the recent progress in understanding the roles of selected gene products in the regulation of water balance and their relevance in clinical practice.
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iPhone Nephrology Clinical Calculator
Successful Delivery of RRT in Ebola Virus Disease
Stage IV Chronic Kidney Disease (Source: Nephrology Now)
Source: Nephrology Now - May 8, 2015 Category: Urology & Nephrology Authors: Nephrology Now editors Tags: Clinical Nephrology Fluid & Electrolytes General Nephrology Source Type: research
IMAGES IN CLINICAL MEDICINE Lindsay ’s Nails in Chronic Kidney Disease
This image says it all. An interesting nail bed finding in CKD.
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Intestinal radiopacities in chronic renal failure
Case Records of the Massachusetts General Hospital. Case 35-2015: A 72-Year-Old Woman with Proteinuria and a Kidney Mass.
Warfarin use, mortality, bleeding and stroke in haemodialysis patients with atrial fibrillation (Source: Nephrology Now)
Source: Nephrology Now - May 8, 2015 Category: Urology & Nephrology Authors: Nephrology Now editors Tags: Chronic Kidney Disease Clinical Nephrology Source Type: research
IMAGES IN CLINICAL MEDICINE Lindsay’s Nails in Chronic Kidney Disease
This image says it all. An interesting nail bed finding in CKD.
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Intestinal radiopacities in chronic renal failure
Warfarin use, mortality, bleeding and stroke in haemodialysis patients with atrial fibrillation
Use of phosphate-binding agents is associated with a lower risk of mortality (Source: Nephrology Now)
Source: Nephrology Now - May 8, 2015 Category: Urology & Nephrology Authors: Nephrology Now editors Tags: Chronic Kidney Disease Clinical Nephrology Source Type: research
Less-Tight versus Tight Control of Hypertension in Pregnancy
This open, multicentre trial assigned women with nonproteinuric or gestatational hypertension to less tight control (target diastolic BP 100 mmHg) vs tight control (target diastolic BP 85 mmHg) with no difference observed in the primary outcome of pregnancy loss, high level neonatal care or overall maternal complications (secondary outcome). However, the less tight control group did have a higher frequency of severe maternal hypertension (40.6% vs 27.5%, p<0.001).
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High versus Low Blood-Pressure Target in Patients with Septic Shock
Vitamins C and E to Prevent Complications of Pregnancy-Associated Hypertension...
Source: Nephrology Now - March 18, 2015 Category: Urology & Nephrology Authors: Nephrology Now editors Tags: Clinical Nephrology Clinical Trial Results General Nephrology Hypertension Pregnancy and Hypertension/Renal Disease Source Type: research
Acid –Base Problems in Diabetic Ketoacidosis
This review focuses on three issues facing clinicians who care for patients with diabetic ketoacidosis: (1) the plasma anion gap, (2) the administration of sodium bicarbonate and (3) the possible contribution of intracellular acidosis to the development of cerebral edema.
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Daily oral sodium bicarbonate preserves glomerular filtration rate by slowing its decline in early hypertensive nephropathy
Sodium Bicarbonate Plus Isotonic Saline Versus Saline for Prevention of Contrast-Induced Nephropathy in Patients Undergoing Coronary Angiography: A Randomized Controlled Trial
Sodium Bicarbonate for the Prevention of Contrast Indu...
Source: Nephrology Now - March 18, 2015 Category: Urology & Nephrology Authors: Nephrology Now editors Tags: Clinical Nephrology Fluid & Electrolytes General Nephrology Review Source Type: research
Acid–Base Problems in Diabetic Ketoacidosis
This review focuses on three issues facing clinicians who care for patients with diabetic ketoacidosis: (1) the plasma anion gap, (2) the administration of sodium bicarbonate and (3) the possible contribution of intracellular acidosis to the development of cerebral edema.
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Daily oral sodium bicarbonate preserves glomerular filtration rate by slowing its decline in early hypertensive nephropathy
Sodium Bicarbonate Plus Isotonic Saline Versus Saline for Prevention of Contrast-Induced Nephropathy in Patients Undergoing Coronary Angiography: A Randomized Controlled Trial
Sodium Bicarbonate for the Prevention of Contrast Indu...
Source: Nephrology Now - March 18, 2015 Category: Urology & Nephrology Authors: Nephrology Now editors Tags: Clinical Nephrology Fluid & Electrolytes General Nephrology Review Source Type: research
Trimethoprim-sulfamethoxazole and risk of sudden death among patients taking spironolactone
Compared with amoxicillin, trimethoprim-sulfamethoxazole was associated with a twofold increase of sudden death (adjusted OR 2.46, 95 % CI 1.55-3.90) as a consequence of hyperkalemia in this population-based study of patients over the age of 65 on spironolactone.
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Trimethoprim-Sulfamethoxazole-Induced Hyperkalemia in Patients Receiving Inhibitors of the Renin-Angiotensin System: A Population-Based Study
ESRD and Death after Heart Failure in CKD
The safety of combining angiotensin-converting-enzyme inhibitors with angiotensin-receptor blockers in elderly patients: a population-based longitudinal analysis (Source: Nephrology Now)
Source: Nephrology Now - March 18, 2015 Category: Urology & Nephrology Authors: Nephrology Now editors Tags: Clinical Nephrology Fluid & Electrolytes General Nephrology Source Type: research
Peritoneal dialysis catheter implantation by nephrologists is associated with higher rates of peritoneal dialysis utilization: a population-based study
This population-based retrospective cohort study using administrative data looked at 3886 PD catheter insertions between 2002-2010. The findings suggest that insertions by nephrologists resulted in lower overall PD nonuse rates. The authors suggest that this greater use may be related to timing/technique of insertion or the greater desire on the part of a nephrologist for a successful PD start.
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Peritoneal Dialysis Access Guide
Randomized Controlled Trial Comparing Mupirocin and Polysporin Triple Ointments in Peritoneal Dialysis Patients: The MP3 Study
Similar Outcomes With Hemodialysis and Peritoneal Dialysis in Pat...
Source: Nephrology Now - March 18, 2015 Category: Urology & Nephrology Authors: Nephrology Now editors Tags: Clinical Nephrology Peritoneal Dialysis Source Type: research
Warfarin use, mortality, bleeding and stroke in haemodialysis patients with atrial fibrillation
This interesting study of hemodialysis patients on oral anticoagulation for atrial fibrillation showed that although their overall mortality was high – it was not associated with warfarin. In fact, warfarin was associated with better survival and antiplatelet agents increased overall mortality.
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The intersection of risk and benefit: is warfarin anticoagulation suitable for atrial fibrillation in patients on hemodialysis?
Effects of Antiplatelet Therapy on Mortality and Cardiovascular and Bleeding Outcomes in Persons With Chronic Kidney Disease: A Systematic Review and Meta-analysis
Stroke and Bleeding in Atrial Fib...
Source: Nephrology Now - March 18, 2015 Category: Urology & Nephrology Authors: Nephrology Now editors Tags: Clinical Nephrology Hemodialysis Source Type: research
Emerging treatments for amyloidosis
This review briefs us on the novel approaches for the treatment of amyloidosis. These targeted therapies may be better options for a disease that frequently has a very poor prognosis.
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Focal Segmental Glomerulosclerosis
Therapeutic Strategies for Heart Failure in Cardiorenal Syndromes
Current Therapy for IgA Nephropathy (Source: Nephrology Now)
Source: Nephrology Now - March 18, 2015 Category: Urology & Nephrology Authors: Nephrology Now editors Tags: Acute Kidney Injury Clinical Nephrology General Nephrology Review Source Type: research
Renal dysfunction in cirrhosis is not just a vasomotor nephropathy
This mini-review discusses the factors implicated in the development of hepatorenal syndrome in patients with progressive cirrhosis.
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Non-selective β Blockers Increase Risk for Hepatorenal Syndrome and Death in Patients with Cirrhosis and Spontaneous Bacterial Peritonitis
Treatment of severe alcoholic hepatitis with corticosteroids and pentoxifylline.
A single-blind randomized controlled trial to evaluate the effect of 6 months of progressive aerobic exercise training in patients with uraemic restless legs syndrome (Source: Nephrology Now)
Source: Nephrology Now - March 18, 2015 Category: Urology & Nephrology Authors: Nephrology Now editors Tags: Acute Kidney Injury Clinical Nephrology Review Source Type: research
ESRD and Death after Heart Failure in CKD
This retrospective study of a Toronto CKD population showed that heart failure hospitalizations were associated with a stepwise increase in the risk of ESRD and death before ESRD (adjusted hazard ratio of ESRD from 4.89 to 10.27 to 14.16 and the adjusted hazard ratio death before ESRD from 3.30 to 4.20 to 6.87 for one two or three or more heart failure hospitalizations respectively.
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Persistent Asymptomatic Isolated Microscopic Hematuria in Israeli Adolescents and Young Adults and Risk for End-Stage Renal Disease
Survival advantage of hemodialysis relative to peritoneal dialysis in patients with end-stage renal disease a...
Source: Nephrology Now - March 18, 2015 Category: Urology & Nephrology Authors: Nephrology Now editors Tags: Chronic Kidney Disease Clinical Nephrology Clinical Trial Results General Nephrology Source Type: research
CKD in Elderly Patients Managed without Dialysis: Survival, Symptoms, and Quality of Life
This is a very important prospective observational study looking at conservative management in a predialysis population managed without dialysis. The elderly population that chose not to initiate dialysis survived a median of 16 months in part due to palliative care that provided “reasonable” symptom management and quality of life.
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Quality of Life and Survival in Patients with Advanced Kidney Failure Managed Conservatively or by Dialysis
Is Maximum Conservative Management an Equivalent Treatment Option to Dialysis for Elderly Patients with Significant Comorbid Disease?
New DaVita Peritoneal Dialysis Webinar Series...
Source: Nephrology Now - March 18, 2015 Category: Urology & Nephrology Authors: Nephrology Now editors Tags: General Nephrology Source Type: research
