Helicobacter pylori and diabetes mellitus: a controversial relationship.
Authors: Valenzano M, Bisio A, Grassi G Abstract Research on Helicobacter pylori (H. pylori), a pathogenic bacterium that is widespread among humans, is investigating the medical implications of the infection in many fields beyond gastroenterology. Because of the ubiquitous presence of the infection, there is an increasing interest in finding a relationship between this bacterium and diabetes mellitus (DM). It is not clear whether a significant relation between H. pylori and DM exists, whether the infection influences diabetes or vice versa, and the mechanisms underlying such a relationship. This review pr...
Source: Minerva Endocrinologica - July 17, 2019 Category: Endocrinology Tags: Minerva Endocrinol Source Type: research

A new perspective on the prevalence of metabolic disturbances in Polish young adults.
Authors: Płaczkowska S, Pawlik-Sobecka L, Kokot I, Piwowar A Abstract PMID: 31304728 [PubMed - in process] (Source: Minerva Endocrinologica)
Source: Minerva Endocrinologica - July 17, 2019 Category: Endocrinology Tags: Minerva Endocrinol Source Type: research

Diabetes mellitus and susceptibility to hemorrhagic stroke: a MiR126 affair?
Authors: Mormile R PMID: 31304729 [PubMed - in process] (Source: Minerva Endocrinologica)
Source: Minerva Endocrinologica - July 17, 2019 Category: Endocrinology Tags: Minerva Endocrinol Source Type: research

Type 1 diabetes mellitus and thyroid diseases: relationship between glycometabolism and thyroid function.
Authors: Tromba V, Silvestri F, Costantino F Abstract PMID: 31286754 [PubMed - as supplied by publisher] (Source: Minerva Endocrinologica)
Source: Minerva Endocrinologica - July 11, 2019 Category: Endocrinology Tags: Minerva Endocrinol Source Type: research

Coping strategies in people with type 1 diabetes on insulin pump treatment.
CONCLUSIONS: Assessing coping strategies preferably used by PWD is useful to select PWD in need of counseling and empowerment-oriented training in order to improve glycemic outcomes and decrease severe hypo/hyperglycemic events. PMID: 31240899 [PubMed - as supplied by publisher] (Source: Minerva Endocrinologica)
Source: Minerva Endocrinologica - June 27, 2019 Category: Endocrinology Tags: Minerva Endocrinol Source Type: research

Diabetes mellitus and osteoporosis.
Authors: Paschou SΑ, Vryonidou A Abstract PMID: 31240900 [PubMed - as supplied by publisher] (Source: Minerva Endocrinologica)
Source: Minerva Endocrinologica - June 27, 2019 Category: Endocrinology Tags: Minerva Endocrinol Source Type: research

Management of diabetes mellitus in chronic kidney disease: an overview.
Authors: Garla VV, Kanduri S, Yanes-Cardozo L, Lien LF Abstract Diabetes mellitus (DM) and Chronic Kidney Disease (CKD) are two chronic diseases whose prevalence and co-prevalence are on the rise. CKD is also the most debilitating and expensive complication of DM while management of DM in CKD is most challenging. CKD is developing in much younger patients with DM, and its presentation is also changing. Various methods of glycemic assessment are affected by CKD and dosage of DM medications needs to be adjusted according to the kidney function. One of the significant barriers to glycemic control in DM patien...
Source: Minerva Endocrinologica - May 23, 2019 Category: Endocrinology Tags: Minerva Endocrinol Source Type: research

Pycnogenol ® prevents oxidative stress and side effects in patients with hypothyroidism during levothyroxine treatment.
CONCLUSIONS: Pycnogenol® may represent a useful tool to reduce LT4- related side effects in patients treated with hormone replacement therapy for hypothyroidism. PMID: 31099529 [PubMed - in process] (Source: Minerva Endocrinologica)
Source: Minerva Endocrinologica - May 18, 2019 Category: Endocrinology Tags: Minerva Endocrinol Source Type: research

Emerging incretin hormones actions: focus on bone metabolism.
Authors: Grammatiki M, Antonopoulou V, Kotsa K Abstract Incretin hormones, namely glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) are gastro-intestinal hormones released from different enteroendocrine cells after nutrient intake. Incretins exert their actions though binding to and activation of specific GIP and GLP-1 receptors which are present in several target tissues. Incretin receptor activation in the pancreas leads to the incretin effect and other significant non-insulinotropic effects. Extra-pancreatic effects of incretin hormones in several other target tissue...
Source: Minerva Endocrinologica - April 18, 2019 Category: Endocrinology Tags: Minerva Endocrinol Source Type: research

Current concepts in the diagnosis and management of neuroendocrine neoplasms of unknown primary.
Authors: Alexandraki KI, Tsoli M, Kyriakopoulos G, Angelousi A, Nikolopoulos G, Kolomodi D, Kaltsas GA Abstract Neuroendocrine neoplams (NENs) of unknowm primary origin (UPO-NENs) are advanced neoplasms constituting 11%-22% of all NENs that by definition their primary tissue of origin has not been identified with standard diagnostic work-up. Delineating the primary site of origin of UPO-NENs has important implications for selecting the appropriate treatment and overall prognosis. The small bowel, followed by the lung and pancreas are the most prevalent primary sites of origin of UPO-NENs that are uncovered...
Source: Minerva Endocrinologica - April 18, 2019 Category: Endocrinology Tags: Minerva Endocrinol Source Type: research

Endocrine dysfunctions associated with Hodgkin lymphoma treatment. Experience from an endocrine late effects clinic of a single centre.
Authors: Dias D, Simões-Pereira J, Donato S, Pereira MC Abstract PMID: 30942565 [PubMed - as supplied by publisher] (Source: Minerva Endocrinologica)
Source: Minerva Endocrinologica - April 4, 2019 Category: Endocrinology Tags: Minerva Endocrinol Source Type: research

Ghrelin combined with sodium tanshinone IIA sulfonate pretreatment reduces apoptosis and fractalkine expression induced by high-dose glucose in human umbilical vein endothelial cells.
CONCLUSIONS: Pretreatment of ghrelin combined with STS reduces the apoptosis rate of HUVECs induced by high glucose environment and inhibits the expression of FKN via β-catenin/Wnt signaling pathway. PMID: 30848111 [PubMed - as supplied by publisher] (Source: Minerva Endocrinologica)
Source: Minerva Endocrinologica - March 9, 2019 Category: Endocrinology Tags: Minerva Endocrinol Source Type: research

Adrenal biopsy: performance and use.
Authors: Zhang CD, Delivanis DA, Eiken PW, Atwell TD, Bancos I Abstract The widespread use of cross-sectioning abdominal imaging in recent years has led to the increased detection of adrenal masses. In each case, determining whether a newly identified adrenal mass is benign or malignant is essential for management, but can be challenging. A significant proportion of adrenal lesions remain indeterminate after initial evaluation due to limitations of current imaging modalities. Adrenal biopsy can be considered for further diagnostic workup in select cases, particularly in patients with an active or previousl...
Source: Minerva Endocrinologica - February 9, 2019 Category: Endocrinology Tags: Minerva Endocrinol Source Type: research

Acromegaly in the era of precision medicine.
Authors: Pico A Abstract PMID: 30732428 [PubMed - as supplied by publisher] (Source: Minerva Endocrinologica)
Source: Minerva Endocrinologica - February 9, 2019 Category: Endocrinology Tags: Minerva Endocrinol Source Type: research

Molecular determinants of the response to medical treatment of growth hormone secreting pituitary neuroendocrine tumors.
Authors: Fuentes-Fayos AC, García-Martínez A, Herrera-Martínez AD, Jiménez-Vacas JM, Vazquez-Borrego MC, Castaño JP, Picó A, Gahete MD, Luque RM Abstract Acromegaly is a chronic systemic disease mainly caused by a growth hormone (GH)- secreting pituitary neuroendocrine tumor (PitNETs), which is associated with many health complications and increased mortality when not adequately treated. Transsphenoidal surgery is considered the treatment of choice in GH-secreting PitNETs, but patients in whom surgery cannot be considered or with persistent disease after surgery require medical therapy. Treatment wit...
Source: Minerva Endocrinologica - January 19, 2019 Category: Endocrinology Tags: Minerva Endocrinol Source Type: research