Utility of neutralization test for laboratory diagnosis of suspected mumps
Microbiology and Immunology, EarlyView. (Source: Microbiology and Immunology)
Source: Microbiology and Immunology - March 8, 2018 Category: Microbiology Source Type: research
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Microbiology and Immunology, Ahead of Print. (Source: Microbiology and Immunology)
Source: Microbiology and Immunology - March 8, 2018 Category: Microbiology Source Type: research
Utility of neutralization test for laboratory diagnosis of suspected mumps
This study was performed to compare the diagnostic utility of a focus reduction neutralization test (FRNT) to that of MuV‐specific commercial IgM and IgG antibody EIA in patients suspected of having mumps. One hundred‐eighty six samples collected during mumps outbreak in 2012–16 were studied. Samples (n = 80) were tested by all the three serological assays and showed 70.4%, 83% and 92.5% positivity by IgM EIA, IgG and FRNT, respectively. In all, 58.8% samples (n = 47) tested positive in all three assays. Concordance between mumps RT‐PCR and IgM EIA was highest during the first 2–5 days and decreased with ...
Source: Microbiology and Immunology - March 8, 2018 Category: Microbiology Authors: Sunil R. Vaidya, Venkat S. Hamde, Neelakshi S. Kumbhar, Atul M. Walimbe Tags: Original Article Source Type: research
Reactive oxygen species ‐induced parthanatos of immunocytes by human cytomegalovirus‐associated substance
Microbiology and Immunology, EarlyView. (Source: Microbiology and Immunology)
Source: Microbiology and Immunology - March 2, 2018 Category: Microbiology Source Type: research
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Microbiology and Immunology, Ahead of Print. (Source: Microbiology and Immunology)
Source: Microbiology and Immunology - March 2, 2018 Category: Microbiology Source Type: research
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Microbiology and Immunology,Volume 62, Issue 2, Page 137-140, February 2018. (Source: Microbiology and Immunology)
Source: Microbiology and Immunology - February 15, 2018 Category: Microbiology Source Type: research
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Microbiology and Immunology,Volume 62, Issue 2, Page i-i, February 2018. (Source: Microbiology and Immunology)
Source: Microbiology and Immunology - February 15, 2018 Category: Microbiology Source Type: research
Issue Information – Instruction for Authors
(Source: Microbiology and Immunology)
Source: Microbiology and Immunology - February 15, 2018 Category: Microbiology Tags: Issue Information – Instruction for Authors Source Type: research
Attenuated accumulation of regulatory T cells and reduced production of interleukin 10 lead to the exacerbation of tissue injury in a mouse model of acute respiratory distress syndrome
ABSTRACT
Acute respiratory distress syndrome (ARDS) is a pathological condition that involves diffuse lung injury and severe hypoxemia caused by pulmonary and systemic diseases. We have established a mouse model of severe ARDS, developed by intratracheal injection of α‐galactosylceramide (α‐GalCer), an activator of natural killer T (NKT) cells, followed by LPS. In the present study, we used this model to investigate the regulatory mechanism in the early inflammatory response during acute lung injury. In α‐GalCer/LPS‐treated mice, the number of CD4+CD25+Foxp3+ regulatory T (Treg) cells and the expression of a Tre...
Source: Microbiology and Immunology - February 15, 2018 Category: Microbiology Authors: Masahiko Toyama, Daisuke Kudo, Tetsuji Aoyagi, Tomomitsu Miyasaka, Keiko Ishii, Emi Kanno, Mitsuo Kaku, Shigeki Kushimoto, Kazuyoshi Kawakami Tags: Original Article Source Type: research
Issue Information – Cover
Cover photograph: Histopathological examinations were performed after immunization with HPV vaccines in mice. HPV vaccines induced inflammatory nodules 3‐6 h after immunization and polymorphonuclear neutrophils with some eosinophils infiltrated. Muscle tissue was stained by Hoechst 33342. Round‐shaped spots of inflammatory cells are observed and morphologically irregular stains suggest the release of DNA from neutrophils, namely neutrophil extracellular traps (NETs). Microbiol Immunol: 62: 124‐131. Article link here. (Source: Microbiology and Immunology)
Source: Microbiology and Immunology - February 15, 2018 Category: Microbiology Tags: Cover Image Source Type: research
Protective efficacy of a DNA vaccine encoding capsid protein of porcine circovirus ‐like virus P1 against porcine circovirus 2 in mice
ABSTRACT
The capsid protein is the major immunogenic protein of porcine circovirus 2 (PCV2). The nucleotide sequence of porcine circovirus‐like virus P1 shares high homology with open reading frame (ORF) 2 of PCV2, and ORF1 of P1 encodes its structural protein. Mice were vaccinated twice intramuscularly with a plasmid expressing the P1 ORF1 protein (pcDNA3.1(+)‐ORF1) at 2‐week intervals. All animals vaccinated with pcDNA3.1(+)‐ORF1 developed higher specific anti‐P1 antibody levels, and had less PCV2 viremia and milder histopathological changes than PCV2‐challenged mice in the control group. Our results show tha...
Source: Microbiology and Immunology - February 15, 2018 Category: Microbiology Authors: Dan Zhang, Kongwang He, Libin Wen, Hongjie Fan Tags: Note Source Type: research
