Characterization and evaluation of tissue-mimicking gelatin phantoms for use with MRgFUS
Conclusion These evaporated milk-modified gelatin phantoms should serve as reliable, general soft tissue-mimicking MRgFUS phantoms. (Source: Journal of Therapeutic Ultrasound)
Source: Journal of Therapeutic Ultrasound - June 16, 2015 Category: Radiology Source Type: research

High-intensity focused ultrasound ablation enhancement in vivo via phase-shift nanodroplets compared to microbubbles
Conclusions Results indicate that the nanodroplet formulation studied here can substantially increase thermal delivery at the acoustic focus while avoiding prefocal heating. In contrast, microbubbles resulted in greater prefocal heating and less heating at the target. Furthermore, nanodroplets are sufficiently stable to enhance HIFU ablation in vivo for at least 1.5 h after injection. The use of a dual-perfluorocarbon nanodroplet formulation as described herein could substantially reduce HIFU procedure times without increasing the risk of skin burns. (Source: Journal of Therapeutic Ultrasound)
Source: Journal of Therapeutic Ultrasound - May 27, 2015 Category: Radiology Source Type: research

High-intensity focused ultrasound for the treatment of fibroadenomata (HIFU-F) study
Abstract Background Breast fibroadenomata (FAD) are the most common benign lesions in women. For palpable lesions, there are currently three standard treatment options: reassurance (with or without follow-up), vacuum-assisted mammotomy (VAM) or surgical excision. High-intensity focused ultrasound (HIFU) ablation has been used in the treatment of FAD. The drawback of HIFU is its prolonged treatment duration. The aim of this trial is to evaluate circumferential HIFU treatment for the effective ablation of FAD with a reduced treatment time. ...
Source: Journal of Therapeutic Ultrasound - April 14, 2015 Category: Radiology Source Type: research

Quality of MR thermometry during palliative MR-guided high-intensity focused ultrasound (MR-HIFU) treatment of bone metastases
Conclusions In this study, the general image quality of MRT was observed to be higher in osteolytic lesions and lower in the upper body. Respiratory time-varying field inhomogeneity was the most prominent MRT artifact. Patient motion occurrence varied between treatments and seemed to be related to lesion type and type of PSA. Clinicians should be aware of these observed characteristics when interpreting MRT images. (Source: Journal of Therapeutic Ultrasound)
Source: Journal of Therapeutic Ultrasound - March 24, 2015 Category: Radiology Source Type: research

Volume reduction of benign thyroid nodules 3 months after a single treatment with high-intensity focused ultrasound (HIFU)
Conclusions HIFU treatment of benign predominantly solid TNs appears to be safe and effective for inducing nodular shrinkage. Despite potential for improvement, a single treatment session with HIFU is already a viable alternative to more standard methods. The feasibility of multiple HIFU treatments requires further investigation. Due to the small sample size, the findings of this analysis need conformation by larger studies. (Source: Journal of Therapeutic Ultrasound)
Source: Journal of Therapeutic Ultrasound - March 4, 2015 Category: Radiology Source Type: research

Removing atherosclerotic plaque created using high cholesterol diet in rabbit using ultrasound
Conclusions The amount of plaque removed is directly related to the acoustic intensity. It was found that the presence of bubbles accelerates the removal of plaque. In order to ensure that pure mechanical mode ultrasound was used, the intensity used does not produce temperatures that exceed 1°C. (Source: Journal of Therapeutic Ultrasound)
Source: Journal of Therapeutic Ultrasound - January 29, 2015 Category: Radiology Source Type: research

Three-axis MR-conditional robot for high-intensity focused ultrasound for treating prostate diseases transrectally
Conclusion An MRI-conditional HIFU robot was developed which can create controlled thermal lesions under MRI guidance. The intention is to use this robot transrectally in the future for the treatment of prostate cancer. (Source: Journal of Therapeutic Ultrasound)
Source: Journal of Therapeutic Ultrasound - January 29, 2015 Category: Radiology Source Type: research

Ultrasound-guided high-intensity focused ultrasound treatment of breast fibroadenoma—a multicenter experience
Conclusions US-guided HIFU treatment is an effective noninvasive method for the treatment of breast FA and well tolerated by the patients. Preliminary results are encouraging and show that HIFU could be an alternative to surgery for breast FA. (Source: Journal of Therapeutic Ultrasound)
Source: Journal of Therapeutic Ultrasound - January 22, 2015 Category: Radiology Source Type: research

Non invasive palliation for advanced pancreatic cancer using high intensity focused ultrasound
(Source: Journal of Therapeutic Ultrasound)
Source: Journal of Therapeutic Ultrasound - December 10, 2014 Category: Radiology Source Type: research

Setting up a new MRgFUS service for fibroids - the challenges and solutions
(Source: Journal of Therapeutic Ultrasound)
Source: Journal of Therapeutic Ultrasound - December 10, 2014 Category: Radiology Source Type: research

Non-invasive treatment of uterine fibroids using MR guided high intensity focused ultrasound: results on quality of life, non-perfused volume ratio and size reduction over 12 months
(Source: Journal of Therapeutic Ultrasound)
Source: Journal of Therapeutic Ultrasound - December 10, 2014 Category: Radiology Source Type: research

A moveable surface coil fabrication for MR-guided HIFU ablation
(Source: Journal of Therapeutic Ultrasound)
Source: Journal of Therapeutic Ultrasound - December 10, 2014 Category: Radiology Source Type: research

MRgFUS of osteoid osteoma started at the Rizzoli
(Source: Journal of Therapeutic Ultrasound)
Source: Journal of Therapeutic Ultrasound - December 10, 2014 Category: Radiology Source Type: research

Inertial cavitation detection during in-vitro sonothrombolysis
(Source: Journal of Therapeutic Ultrasound)
Source: Journal of Therapeutic Ultrasound - December 10, 2014 Category: Radiology Source Type: research

MRI-guided focused ultrasound (MRgFUS) surgery in conserving therapy of adenomyosis
(Source: Journal of Therapeutic Ultrasound)
Source: Journal of Therapeutic Ultrasound - December 10, 2014 Category: Radiology Source Type: research