MRI-guided coupling for a focused ultrasound system using a top-to-bottom propagation
ConclusionsAn MRI-conditional FUS coupling system integrated with an existing robotic system was developed that has the potential to create thermal lesions in targets using a top-to-bottom approach. This system has the potential to treat fibroid tumors with the patient lying in supine position. (Source: Journal of Therapeutic Ultrasound)
Source: Journal of Therapeutic Ultrasound - January 22, 2017 Category: Radiology Source Type: research

Rapid full-wave phase aberration correction method for transcranial high-intensity focused ultrasound therapies
ConclusionsThe method presented here is able to rapidly compute phases required to improve ultrasound focusing through the skull at multiple treatment locations. Combining phase correction with rapid simulation techniques allows for evaluation of various treatment metrics such as the effect of steering on pressure levels. Since the method computes 3D pressure patterns, it may also be suitable for predicting off-focus hot spots during treatments —a primary concern for transcranial HIFU. Additionally, the plastic-skull method presented here may be a useful tool in evaluating the effectiveness of phase correction methods. (...
Source: Journal of Therapeutic Ultrasound - December 7, 2016 Category: Radiology Source Type: research

Fast and high temperature hyperthermia coupled with radiotherapy as a possible new treatment for glioblastoma
DiscussionHigh priority should be given to experiments to validate the therapeutic benefit predicted by our model. (Source: Journal of Therapeutic Ultrasound)
Source: Journal of Therapeutic Ultrasound - December 7, 2016 Category: Radiology Source Type: research

Uncertainty estimation for temperature measurement with diagnostic ultrasound
ConclusionsTemperature measurements using the echo-time-shift method might be useful for validation of treatment plan algorithms. This might also be a comparatively accurate, fast, and affordable method for laboratory and clinical quality assessment. Further research is necessary to improve filter algorithms and to extend this method to multiple foci and the usage of temperature-dependent tissue quantities. We used an analytical approach to investigate the uncertainties of temperature measurement. Different analysis variations are compared to determine temperature distribution and development over time. (Source: Journal of...
Source: Journal of Therapeutic Ultrasound - November 30, 2016 Category: Radiology Source Type: research

T2-based temperature monitoring in bone marrow for MR-guided focused ultrasound
ConclusionsIn this study, we have demonstrated that T2-based thermometry can be used in vivo to measure the heating in the marrow during bone ablation. The ability to monitor the temperature within the bone marrow allowed more complete visualization of the heat distribution into the bone, which is important for local lesion control. (Source: Journal of Therapeutic Ultrasound)
Source: Journal of Therapeutic Ultrasound - November 16, 2016 Category: Radiology Source Type: research

The safety and effectiveness of volumetric magnetic resonance-guided high-intensity focused ultrasound treatment of symptomatic uterine fibroids: early clinical experience in China
ConclusionsThis study demonstrated that the volumetric magnetic resonance-guided high-intensity focused ultrasound device is safe and technically effective and can be utilized in clinically efficient treatments of symptomatic uterine fibroids.Trial registrationNCT01588899 (Source: Journal of Therapeutic Ultrasound)
Source: Journal of Therapeutic Ultrasound - November 2, 2016 Category: Radiology Source Type: research

5th International Symposium on Focused Ultrasound
(Source: Journal of Therapeutic Ultrasound)
Source: Journal of Therapeutic Ultrasound - October 31, 2016 Category: Radiology Source Type: research

Low-intensity pulsed ultrasound stimulation in different regions in the viability of myocutaneous flaps
ConclusionsIn view of our results, one can conclude that the application of LIPUS at the center of the flap was effective for the viability of TRAM flap in reducing the necrosis area. (Source: Journal of Therapeutic Ultrasound)
Source: Journal of Therapeutic Ultrasound - October 20, 2016 Category: Radiology Source Type: research

Erratum to: Open-source, small-animal magnetic resonance-guided focused ultrasound system
(Source: Journal of Therapeutic Ultrasound)
Source: Journal of Therapeutic Ultrasound - October 18, 2016 Category: Radiology Source Type: research

The influence of low-intensity physiotherapeutic ultrasound on the initial stage of bone healing in rats: an experimental and simulation study
ConclusionsThirteen days after fracture, there was no significant between-group differences in bone-healing processes, although the increased alkaline phosphatase levels and diameter of new bone tissue need to be further investigated. (Source: Journal of Therapeutic Ultrasound)
Source: Journal of Therapeutic Ultrasound - October 2, 2016 Category: Radiology Source Type: research

MR thermometry for focused ultrasound monitoring utilizing model predictive filtering and ultrasound beam modeling
ConclusionsHAS simulations can be used to accurately predict the focal spot location in homogeneous media and when focusing through an aberrating plastic skull. The HAS simulated power deposition (Q) patterns can be used in the MPF thermal model-based reconstruction to obtain accurate temperature maps with high spatio-temporal resolution over large FOVs. (Source: Journal of Therapeutic Ultrasound)
Source: Journal of Therapeutic Ultrasound - September 21, 2016 Category: Radiology Source Type: research

Open-source, small-animal magnetic resonance-guided focused ultrasound system
ConclusionsWe developed an MRgFUS platform for small-animal treatments that robustly delivers accurate, precise, and controllable sonications over extended time periods. This system is an open source and could increase the availability of low-cost small-animal systems to interdisciplinary researchers seeking to develop new MRgFUS applications and technology. (Source: Journal of Therapeutic Ultrasound)
Source: Journal of Therapeutic Ultrasound - September 4, 2016 Category: Radiology Source Type: research

Influence of therapeutic ultrasound on the biomechanical characteristics of the skin
ConclusionsTherapeutic ultrasound promotes significant alterations of the biomechanical characteristics of the skin.Trial registrationClinicalTrials.gov,1111-1146-7342 (Source: Journal of Therapeutic Ultrasound)
Source: Journal of Therapeutic Ultrasound - August 16, 2016 Category: Radiology Source Type: research

Volumetric MR-guided high-intensity focused ultrasound ablation to treat uterine fibroids through the abdominal scars using scar patch: a case report
ConclusionsOur preliminary experience suggests that the use of scar patch on MR-HIFU ablation of fibroids using volumetric technique provides an effective treatment option for patients who were previously excluded from MR-HIFU treatment due to the abdominal scars. (Source: Journal of Therapeutic Ultrasound)
Source: Journal of Therapeutic Ultrasound - August 10, 2016 Category: Radiology Source Type: research

Procedural sedation and analgesia for respiratory-gated MR-HIFU in the liver: a feasibility study
Conclusions < /h3 > < p class= " a-plus-plus " > We conclude that MR-HIFU ablations of the liver under PSA are feasible and potentially increase the non-invasive nature of this type of intervention. < /p > < /span > (Source: Journal of Therapeutic Ultrasound)
Source: Journal of Therapeutic Ultrasound - July 28, 2016 Category: Radiology Source Type: research