Development of a high-field MR-guided HIFU setup for thermal and mechanical ablation methods in small animals
Conclusion
A stable small animal MR-guided HIFU setup was designed and evaluated for follow-up MR imaging and histopathologic responses of the treated tumors. This will facilitate further studies with a larger number of mice for detailed evaluation of the pathologic and immunologic response to different HIFU strategies. (Source: Journal of Therapeutic Ultrasound)
Source: Journal of Therapeutic Ultrasound - August 13, 2015 Category: Radiology Source Type: research
Effects of magnetic resonance-guided high-intensity focused ultrasound ablation on bone mechanical properties and modeling
Conclusions
Multimodality imaging and histological data illustrated the presence of HIFU-induced bone damage at the cellular level, which activated the bone repair mechanisms. Despite that, these changes did not have a mechanical impact on the bone. (Source: Journal of Therapeutic Ultrasound)
Source: Journal of Therapeutic Ultrasound - August 10, 2015 Category: Radiology Source Type: research
Stimulation of osteoblast differentiation with guided ultrasound waves
Conclusion
We demonstrate herein that ultrasound in a form of guided Lamb waves is capable of inducing osteoblast differentiation in vitro, and it may enable the stimulation of osteoblasts in vivo over a distance from the site of ultrasound application. (Source: Journal of Therapeutic Ultrasound)
Source: Journal of Therapeutic Ultrasound - August 5, 2015 Category: Radiology Source Type: research
Full-wave acoustic and thermal modeling of transcranial ultrasound propagation and investigation of skull-induced aberration correction techniques: a feasibility study
Conclusions
Simulation-based approaches to calculate aberration corrections may aid in the extension of the tcFUS treatment envelope as well as predict and avoid secondary effects (standing waves, skull heating). Due to their superior performance, simulationbased techniques may prove invaluable in the amelioration of skull-induced aberration effects in tcFUS therapy. The next steps are to investigate shear-wave-induced effects in order to reliably exclude secondary hot-spots, and to develop comprehensive uncertainty assessment and validation procedures. (Source: Journal of Therapeutic Ultrasound)
Source: Journal of Therapeutic Ultrasound - July 31, 2015 Category: Radiology Source Type: research
Potential of focused ultrasound in epilepsy surgery
(Source: Journal of Therapeutic Ultrasound)
Source: Journal of Therapeutic Ultrasound - June 30, 2015 Category: Radiology Source Type: research
In vivo l ow frequency MR-guided thalamotomy with focused ultrasound: thermal vs mechanical lesioning in pig brain
(Source: Journal of Therapeutic Ultrasound)
Source: Journal of Therapeutic Ultrasound - June 30, 2015 Category: Radiology Source Type: research
Pain alleviation and QOL improvement of MR-guided focused ultrasound surgery (MRgFUS) treatment for painful medial compartment of knee osteoarthritis
(Source: Journal of Therapeutic Ultrasound)
Source: Journal of Therapeutic Ultrasound - June 30, 2015 Category: Radiology Source Type: research
AAPM task group 241 – MR-guided focused ultrasound
(Source: Journal of Therapeutic Ultrasound)
Source: Journal of Therapeutic Ultrasound - June 30, 2015 Category: Radiology Source Type: research
Quality assurance and field characterisation for MRgHIFU treatments: their need and the challenges presented
(Source: Journal of Therapeutic Ultrasound)
Source: Journal of Therapeutic Ultrasound - June 30, 2015 Category: Radiology Source Type: research
Expanding the treatment envelope for brain therapy: simulation models and head phantoms
(Source: Journal of Therapeutic Ultrasound)
Source: Journal of Therapeutic Ultrasound - June 30, 2015 Category: Radiology Source Type: research
Safety and feasibility of focused ultrasound neuromodulation in temporal lobe epilepsy
(Source: Journal of Therapeutic Ultrasound)
Source: Journal of Therapeutic Ultrasound - June 30, 2015 Category: Radiology Source Type: research
MRI predictors of clinical success in MR-guided focused ultrasound (MRgFUS) treatments of uterine fibroids: results from a single center
(Source: Journal of Therapeutic Ultrasound)
Source: Journal of Therapeutic Ultrasound - June 30, 2015 Category: Radiology Source Type: research
Assessing temperature dependence of T1 in cortical bone using ultrashort echo-time MRI
(Source: Journal of Therapeutic Ultrasound)
Source: Journal of Therapeutic Ultrasound - June 30, 2015 Category: Radiology Source Type: research
Ultrasound field characterization and bioeffects in multiwell culture plates
Conclusions
This study highlights the pitfalls of using multiwell plates when investigating the biological effect of kilohertz low-frequency ultrasound on adherent cell cultures. (Source: Journal of Therapeutic Ultrasound)
Source: Journal of Therapeutic Ultrasound - June 30, 2015 Category: Radiology Source Type: research
Evaluation of fractionated and repeated sonodynamic therapy by using dual frequency for murine model of breast adenocarcinoma
Conclusion
The ultrasound dose fractionation and repetition technique with dual-frequency sonication can have a useful therapeutic effect in sonodynamic therapy with the possibility of use in future clinical applications. (Source: Journal of Therapeutic Ultrasound)
Source: Journal of Therapeutic Ultrasound - June 24, 2015 Category: Radiology Source Type: research
