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Antihypertensive therapy in nondiabetic chronic kidney disease: a review and update
Hypertension is an important contributor to progression of nondiabetic chronic kidney disease (CKD). Compelling observational evidence indicates that the divergence of blood pressure (BP) away from an ideal range in either direction is associated with a progressive rise in the risk of mortality and cardiovascular and renal disease progression. To date, various clinical trials and meta-analyses examining strict versus less intensive BP control in nondiabetic CKD have not conclusively demonstrated a renal advantage of one BP-lowering approach over another, except in certain subgroups such as proteinuric patients where eviden...
Source: Journal of the American Society of Hypertension - January 21, 2018 Category: Cardiology Authors: Paul J. Der Mesropian, Gulvahid Shaikh, Emmanuelle Cordero Torres, Anum Bilal, Roy O. Mathew Tags: Review Article Source Type: research

2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA Guideline for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults. A report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines
We commend the committee on an outstanding hypertension guideline.1 Nevertheless, we respectively disagree with recommendations regarding low-risk hypertensives and combination therapy. Although the authors espouse a risk-based approach to therapy, largely to justify initial drug treatment of “stage-1 hypertension” in high-risk patients, there is an oversimplification in the approach to “mild hypertension”. All patients with high blood pressure historically considered mild (140–159/90–99 mm Hg)2 are now recommended to immediately begin pharmacologic therapy even if they are aged (Source: Journal of the America...
Source: Journal of the American Society of Hypertension - January 21, 2018 Category: Cardiology Authors: Robert D. Brook, Sanjay Rajagopalan Tags: Letter to the Editor Source Type: research

Varying Blood Pressure in Children: A Diagnostic Quandary Interpreting the Fourth Report
Fourth Report guidelines on pediatric blood pressure (BP) are not clear when defining hypertension in children as “an average systolic BP and/or diastolic BP that is ≥ 95th percentile for gender, age, and height on ≥ 3 occasions.” We aimed to determine the prevalence of pediatric hypertension in a screening population based on two different guideline interpretations. (Source: Journal of the American Society of Hypertension)
Source: Journal of the American Society of Hypertension - January 21, 2018 Category: Cardiology Authors: Sheri L. Balsara, Joshua A. Samuels, Joyce P. Samuel, Cynthia S. Bell Tags: Research Article Source Type: research

Letter to the editors regarding: 2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA Guideline for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults. A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines
We commend the committee on an outstanding hypertension guideline1. Nevertheless, we respectively disagree with recommendations regarding low-risk hypertensives and combination therapy. Although the authors espouse a risk-based approach to therapy, largely to justify initial drug treatment of “stage-1 hypertension” in higher-risk patients, there is an over-simplification in the approach to “mild hypertension”. All patients with high blood pressure historically-considered mild (140-159/90-99 mm Hg)2 are now recommended to immediately begin pharmacologic therapy even if they are (Source: Journal of the American Society of Hypertension)
Source: Journal of the American Society of Hypertension - January 21, 2018 Category: Cardiology Authors: Robert D. Brook, Sanjay Rajagopalan Tags: Letter to the editor Source Type: research

Antihypertensive Therapy in Nondiabetic Chronic Kidney Disease: A Review and Update
Hypertension is an important contributor to progression of nondiabetic chronic kidney disease (CKD). Compelling observational evidence indicates that the divergence of blood pressure (BP) away from an ideal range in either direction is associated with a progressive rise in the risk of mortality and cardiovascular and renal disease progression. To date, various clinical trials and meta-analyses examining strict vs. less intensive BP control in nondiabetic CKD have not conclusively demonstrated a renal advantage of one BP-lowering approach over another, except in certain subgroups such as proteinuric patients where evidence ...
Source: Journal of the American Society of Hypertension - January 21, 2018 Category: Cardiology Authors: Paul J. Der Mesropian, Gulvahid Shaikh, Emmanuelle Cordero Torres, Anum Bilal, Roy O. Mathew Tags: Review Article Source Type: research

Risk factors for arterial hypertension after liver transplantation
Arterial hypertension represents a common complication of immunosuppressive therapy after liver transplantation (LT). The aim of the study is to evaluate the prevalence and risk factors associated with hypertension after LT. From a cohort of 323 cirrhotic patients who underwent LT from 2008 to 2012, 270 patients were retrospectively evaluated, whereas 53 (16.4%) patients deceased. Hypertension was defined as blood pressure ≥140/90 mm Hg in at least two visits and/or the need for antihypertensive therapy. (Source: Journal of the American Society of Hypertension)
Source: Journal of the American Society of Hypertension - January 5, 2018 Category: Cardiology Authors: Cristina Di Stefano, Ester Vanni, Stefano Mirabella, Ramy Younes, Valentina Boano, Elena Mosso, Elisabetta Nada, Valeria Milazzo, Simona Maule, Renato Romagnoli, Mauro Salizzoni, Franco Veglio, Alberto Milan Tags: Research Article Source Type: research

Risk Factors For Arterial Hypertension After Liver Transplantation
Arterial hypertension represents a common complication of immunosuppressive therapy after liver transplantation (LT). The aim of the study is the evaluation of prevalence and risk factors associated with arterial hypertension after LT. (Source: Journal of the American Society of Hypertension)
Source: Journal of the American Society of Hypertension - January 5, 2018 Category: Cardiology Authors: Cristina Di Stefano, Ester Vanni, Stefano Mirabella, Ramy Ibrahim Kamal Jouness, Valentina Boano, Elena Mosso, Elisabetta Nada, Valeria Milazzo, Simona Maule, Renato Romagnoli, Mauro Salizzoni, Franco Veglio, Alberto Milan Tags: Research Article Source Type: research

Hypertension in postmenopausal women: hemodynamic and therapeutic implications
Hypertension is frequent in postmenopausal women, and the characteristics of this particular disease state differ markedly from those observed in men and in premenopausal women.1 Specific features are observed, which are distinct from the roles of autonomic and renin-angiotensin systems,1,2 and are likely the direct consequence of the loss of premenopause estrogen-induced vasoprotection.3 (Source: Journal of the American Society of Hypertension)
Source: Journal of the American Society of Hypertension - January 4, 2018 Category: Cardiology Authors: Veronique Regnault, Patrick Lacolley, Michel E. Safar Tags: Editorial Source Type: research

Hypertension in postmenopausal women: hemodynamic and therapeutic implications
Hypertension is frequent in postmenopausal women and the characteristics of this particular disease state differ markedly from those observed in men and in premenopausal women.1 Specific features are observed, which are distinct from the roles of autonomic and renin-angiotensin systems,1,2 and are likely the direct consequence of the loss of pre-menopause estrogen-induced vasoprotection.3 (Source: Journal of the American Society of Hypertension)
Source: Journal of the American Society of Hypertension - January 4, 2018 Category: Cardiology Authors: V. Regnault, P. Lacolley, M.E. Safar Tags: Editorial Source Type: research

Severe obstructive sleep apnea in children with elevated blood pressure
The objective was to determine the prevalence of habitual snoring and obstructive sleep apnea (OSA) in a cohort of children referred for elevated blood pressure (BP), and to determine the association between OSA and BP elevation, learning difficulties, and behavioral problems. We performed a retrospective review of 446 consecutive new patients referred for elevated BP. One hundred four (23%) had habitual snoring. Patients with habitual snoring were more likely to be obese (86.5 vs. 55.6%, P (Source: Journal of the American Society of Hypertension)
Source: Journal of the American Society of Hypertension - January 3, 2018 Category: Cardiology Authors: Jane Hinkle, Heidi V. Connolly, Heather R. Adams, Marc B. Lande Tags: Research Article Source Type: research

Ambulatory blood pressure variability within the first 24 hours after admission and outcomes of acute ischemic stroke
Our purpose was to evaluate the value of blood pressure variability within the first 24 hours after admission in predicting outcomes of patients with acute ischemic stroke (AIS). A greater variability in systolic blood pressure (adjusted odds ratio [OR] = 1.801, 95% confidence interval [CI] = 1.167–2.779) was associated with poor discharge outcome, especially for nondiabetics (adjusted OR = 1.948, 95% CI = 1.184–3.205) and cardioembolism-related patients with AIS (OR = 7.650, 95% CI = 1.370–42.713). (Source: Journal of the American Society of Hypertension)
Source: Journal of the American Society of Hypertension - January 3, 2018 Category: Cardiology Authors: Yu Zhang, Hong Wang, Ke Xu, Ping Wang, Xin-Yan Li, Jing-Bo Zhao, Ying Tang Tags: Research Article Source Type: research

The prevalence of central hypertension defined by a central blood pressure type I device and its association with target organ damage in the community-dwelling elderly Chinese: The Northern Shanghai Study
We aimed to investigate the prevalence of central hypertension and its association with target organ damage (TOD). 1983 community-dwelling elderly Chinese people were recruited for this analysis. Brachial and central blood pressure (BP) were measured by an oscillometric device and SphygmoCor (type I device), respectively. Brachial hypertension was defined by brachial systolic BP/diastolic BP ≥140/90 mmHg or using antihypertensive medications. Central hypertension was defined by central systolic BP/diastolic BP ≥130/90 mmHg or using antihypertensive medications. (Source: Journal of the American Society of Hypertension)
Source: Journal of the American Society of Hypertension - January 3, 2018 Category: Cardiology Authors: Shikai Yu, Jing Xiong, Yuyan Lu, Chen Chi, Jiadela Teliewubai, Bin Bai, Hongwei Ji, Yiwu Zhou, Ximin Fan, Jacques Blacher, Jue Li, Yi Zhang, Yawei Xu Tags: Research Article Source Type: research

Severe Obstructive Sleep Apnea in Children with Elevated Blood Pressure
The objective was to determine the prevalence of habitual snoring and obstructive sleep apnea (OSA) in a cohort of children referred for elevated BP, and to determine the association between OSA and blood pressure elevation, learning difficulties, and behavioral problems. We performed a retrospective review of 446 consecutive new patients referred for elevated BP. One hundred four (23%) had habitual snoring. Patients with habitual snoring were more likely to be obese (86.5 vs 55.6%, p (Source: Journal of the American Society of Hypertension)
Source: Journal of the American Society of Hypertension - January 3, 2018 Category: Cardiology Authors: Jane Hinkle, Heidi V. Connolly, Heather R. Adams, Marc B. Lande Tags: Research Article Source Type: research

Ambulatory Blood Pressure Variability within the First 24-Hour after Admission and Outcomes of Acute Ischemic Stroke
Our purpose was to evaluate the value of blood pressure variability within the first 24-hour after admission in predicting outcomes of patients with acute ischemic stroke. A greater variability in systolic blood pressure (adjusted odds ratio [OR] = 1.801, 95% confidence interval [CI] = 1.167-2.779) was associated with poor discharge outcome, especially for non-diabetics (adjusted OR =1.948, 95% CI = 1.184-3.205) and cardioembolism-related patients with acute ischemic stroke (OR = 7.650, 95% CI = 1.370-42.713). (Source: Journal of the American Society of Hypertension)
Source: Journal of the American Society of Hypertension - January 3, 2018 Category: Cardiology Authors: Yu Zhang, Hong Wang, Ke Xu, Ping Wang, Xin-Yan Li, Jing-Bo Zhao, Ying Tang Tags: Research Article Source Type: research