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Chronic Kidney Disease as a Cardiovascular Risk Factor: Lessons From Kidney Donors
Chronic kidney disease is a major risk factor for cardiovascular disease but is often associated with other risks such as diabetes and hypertension and can be both a cause and an effect of cardiovascular disease. While epidemiological data of an independent association of reduced glomerular filtration rate with cardiovascular risk are strong, causative mechanisms are unclear. Living kidney donors provide a useful model for assessing the “pure” effects of reduced kidney function on the cardiovascular system. (Source: Journal of the American Society of Hypertension)
Source: Journal of the American Society of Hypertension - May 9, 2018 Category: Cardiology Authors: Anna M. Price, Nicola C. Edwards, Manvir K. Hayer, William E. Moody, Richard P. Steeds, Charles J. Ferro, Jonathan N. Townend Tags: Review Article Source Type: research

Renovascular hypertension in small children – is it Takayasu arteritis or fibromuscular dysplasia?
Renovascular hypertension in children is a rare but very severe condition with systolic blood pressures often reaching 200 mm Hg or higher. There are two major non-syndromic causes to this; Takayasu arteritis (TA) and fibromuscular dysplasia (FMD). These two diagnoses are used with different frequency in North America and Europe compared to Asia and South Africa. This most likely reflects real differences in prevalence of the two conditions but also different diagnostic traditions. TA is defined as an angiographic abnormality not caused by FMD or a similar disease while FMD is a non-atherosclerotic and non-inflammatory art...
Source: Journal of the American Society of Hypertension - May 9, 2018 Category: Cardiology Authors: Kjell Tullus, Derek Roebuck Tags: Commentary Source Type: research

Diastolic blood pressure and risk profile in renal and cardiovascular diseases. Results from the sprint trial
The SPRINT trial demonstrated the efficacy and safety of targeting a systolic blood pressure of (Source: Journal of the American Society of Hypertension)
Source: Journal of the American Society of Hypertension - May 4, 2018 Category: Cardiology Authors: Rita Del Pinto, Davide Pietropaoli, Claudio Ferri Tags: Research Article Source Type: research

Ambulatory Hypertension in a Pediatric Cohort of Sickle Cell Disease
Hypertension is an established risk factor for subsequent cardiovascular and renal disease in children as well as adults. Sickle Cell Disease (SCD) is a genetic disorder associated with chronic hemolytic anemia with the major manifestation of vaso-occlusive crises. While this disease entity involves most organ systems causing vascular and pulmonary injury, little is known about blood pressure (BP) levels or prevalence of hypertension in children with SCD. (Source: Journal of the American Society of Hypertension)
Source: Journal of the American Society of Hypertension - May 4, 2018 Category: Cardiology Authors: Divya G. Moodalbail, Bonita Falkner, Scott W. Keith, Robert S. Mathias, Carlos E. Araya, Joshua J. Zaritsky, Marie J. Stuart Tags: Research Article Source Type: research

The Cardiovascular Health Score And The Volume of Carotid Body In Computed Tomography Angiography In Patients With Arterial Hypertension
The Cardiovascular Health (CVH) Score constitutes a reliable and measurable indicator of cardiovascular health proposed by the American Heart Association (AHA) calculated based on seven fundamental parameters, i.e. smoking, body mass index, physical activity, healthy diet score, blood pressure, blood cholesterol and fasting plasma glucose. The size and activity of carotid body (CB) play a important role in the pathogenesis of the cardiovascular system. (Source: Journal of the American Society of Hypertension)
Source: Journal of the American Society of Hypertension - May 3, 2018 Category: Cardiology Authors: Przemys ław Jaźwiec, Paweł Gać, Małgorzata Poręba, Małgorzata Sobieszczańska, Grzegorz Mazur, Rafał Poręba Tags: Research Article Source Type: research

Is life's simple 7 a practical paradigm for promoting healthy blood pressure, preventing cardiovascular disease and improving total health?
In the Jackson Heart Study, the number of ideal Life's Simple 7 (LS7) components, which includes four lifestyle and three medical factors (Table  1), was strongly related to incident hypertension among 1878 non-hypertensive African American adults.1,2 Compared to adults with 0–1 of seven ideal factors, the risk for incident hypertension fell roughly 20% for those with two, 70% with four and 90% with six of seven ideal factors (Table 2) b ased on multivariable hazard ratios. (Source: Journal of the American Society of Hypertension)
Source: Journal of the American Society of Hypertension - May 1, 2018 Category: Cardiology Authors: Brent M. Egan Tags: Hypertension Highlight Source Type: research

Editorial Board
(Source: Journal of the American Society of Hypertension)
Source: Journal of the American Society of Hypertension - May 1, 2018 Category: Cardiology Source Type: research

Table of Contents
(Source: Journal of the American Society of Hypertension)
Source: Journal of the American Society of Hypertension - May 1, 2018 Category: Cardiology Source Type: research

Instructions for Authors
(Source: Journal of the American Society of Hypertension)
Source: Journal of the American Society of Hypertension - May 1, 2018 Category: Cardiology Source Type: research

Balloon Angioplasty of Renal Artery Stenosis Due to Takayasu Arteritis in a 2-Year-Old Child
The aim of this report is to demonstrate a 2-year-2-month-old child who presented with a history of malignant hypertension. He was made the diagnosis of Takayasu arteritis by laboratory tests and angiography; We initiated a treatment with sequential balloon pre-dilation. The patient's blood pressure improved dramatically, and patency of renal artery was demonstrated with renal arteriography over 8 months after the balloon pre-dilation. (Source: Journal of the American Society of Hypertension)
Source: Journal of the American Society of Hypertension - April 25, 2018 Category: Cardiology Authors: Alimujiang Abudoureyimu, Xingwei he, Jiangtao yan, Chang xu, Liru Qiu, Hesong Zeng Source Type: research

From the Editor
We are well aware of the greater prevalence of hypertension in African-Americans as well as their increased risk for hypertension-related target-organ damage, kidney disease, and death.1 Reducing this glaring health disparity has been a challenge because doing so requires interventions directed at improving hypertension detection and awareness, treatment, and control. (Source: Journal of the American Society of Hypertension)
Source: Journal of the American Society of Hypertension - April 11, 2018 Category: Cardiology Authors: Daniel Levy Tags: Editor's Page Source Type: research

Editor ’s page
We are well aware of the greater prevalence of hypertension in African Americans as well as their increased risk for hypertension related target-organ damage, kidney disease, and death [1]. Reducing this glaring health disparity has been a challenge, because doing so requires interventions directed at improving hypertension detection and awareness, treatment, and control. (Source: Journal of the American Society of Hypertension)
Source: Journal of the American Society of Hypertension - April 11, 2018 Category: Cardiology Authors: Daniel Levy Source Type: research

Significant interaction of hypertension and homocysteine on neurological severity in first-ever ischemic stroke patients
It is not known whether combination of hypertension and high homocysteine (HHcy) impacts on stroke-related neurological severity. Our aim was to determine whether there is an interaction of hypertension and HHcy on neurological severity in first-ever ischemic stroke patients. We analyzed neurological severity among 189 consecutive first-ever ischemic stroke patients with or without hypertension or HHcy. Hypertension (odds ratio [OR]: 8.086, 95% confidence interval [CI]: 3.596 –18.181, P  (Source: Journal of the American Society of Hypertension)
Source: Journal of the American Society of Hypertension - April 3, 2018 Category: Cardiology Authors: Ying-Li Fan, Rui Zhan, Yi-Fei Dong, Lei Huang, Xi-Xin Ji, Peng Lu, Jian Liu, Ping Li, Xiao-Shu Cheng Tags: Research Article Source Type: research

Ethanol withdrawal increases blood pressure and vascular oxidative stress: a role for angiotensin type 1 receptors
We evaluated the possible mechanisms underlying the oxidative stress induced by ethanol withdrawal. With this purpose, we verified the role of AT1 receptors in such response. Male Wistar rats were treated with ethanol 3% –9% (vol./vol.) for 21 days. Ethanol withdrawal was induced by abrupt discontinuation of the treatment. Experiments were performed 48 hours after ethanol discontinuation. Increased plasma levels of angiotensin II were detected after ethanol withdrawal. Losartan (10 mg/kg; p.o. gavage), a selectiv e AT1 receptor antagonist, impeded the increase in blood pressure induced by ethanol withdrawal. (Source: Jo...
Source: Journal of the American Society of Hypertension - April 3, 2018 Category: Cardiology Authors: Nat ália A. Gonzaga, Gabriel T. do Vale, Juliana M. Parente, Rodrigo Yokota, Bruno S. De Martinis, Dulce E. Casarini, Michele M. Castro, Carlos R. Tirapelli Tags: Research Article Source Type: research