Comparison of knee joint orientation in clinically versus biomechanically aligned computed tomography coordinate system
This study aims to establish a relation between the knee-centred clinical coordinate system (CCS) and a biomechanical coordinate system (BCS) based on the Mikulicz line.MethodsCT data sets of 45 lower extremities were evaluated. Using VGStudio Max, a visualisation and measurement software program; each CT data set was aligned according to the CCS and BCS. After superimposing both the aligned data sets, the deviations of both coordinate systems in all three planes were measured with the centre of the knee defined as the origin.FindingsFor the coronal plane, the CCS was demonstrated to be 2.54° in adduction compared to the ...
Source: Journal of Orthopaedic Translation - August 9, 2018 Category: Orthopaedics Source Type: research

Optimal medial transforaminal lumbar interbody fusion approach with five extensive options: A simulated study on three-dimensional digital reconstructed images
ConclusionOur 3D digital image study provides a feasible optimal medial transforaminal lumbar interbody fusion approach with five extensive options on lower lumbar region. It can provide safe lumbar decompression and interbody fusion in most population. In addition, surgeons can choose the different extensive options for special individual conditions. (Source: Journal of Orthopaedic Translation)
Source: Journal of Orthopaedic Translation - August 7, 2018 Category: Orthopaedics Source Type: research

Tendon pathology in hypercholesterolaemia patients: Epidemiology, pathogenesis and management
Publication date: Available online 6 August 2018Source: Journal of Orthopaedic TranslationAuthor(s): Yang Yang, Hongbin Lu, Jin QuAbstractTendon pathology is a general term used to describe a group of musculoskeletal conditions related to tendons and surrounding structures. There is only limited evidence available regarding the exact aetiology and natural history of tendon pathology. In hypercholesterolaemia environments, lipids could accumulate within the extracellular matrix of the tendon and thus affect the mechanical properties of the tendon. Current evidence suggested that hypercholesterolaemia was an important risk f...
Source: Journal of Orthopaedic Translation - August 7, 2018 Category: Orthopaedics Source Type: research

Strain-specific differences in the development of bone loss and incidence of osteonecrosis following glucocorticoid treatment in two different mouse strains
ConclusionGC-induced ON was more prevalent in the male BALB/c mice compared to the male C57BL/6 mice. GC treatment significantly reduced bone mass, bone formation measured by P1NP, bone strength and increased marrow fat levels in male BALB/c mice. Therefore, the use of male BALB/c mice strain is recommended for both diagnostic and therapeutic studies for the prevention and treatment of ON and bone loss following prolonged treatment with GCs.The Translational Potential of this ArticleGCs are commonly used to treat patients with various chronic inflammatory diseases, and this is associated with both the development of ON an...
Source: Journal of Orthopaedic Translation - July 27, 2018 Category: Orthopaedics Source Type: research

Localisation of the radial nerve at the spiral groove: A new technique
ConclusionThe course of the RN can be easily found at the upper arm by this method, which is unique to a patient.The translational potential of this articleThis study presents a new and individualised approach to accurately predict the location of the RN in the spiral groove. This method is clinically relevant and can be used to guide the surgical explorations or expedite interventional methods. (Source: Journal of Orthopaedic Translation)
Source: Journal of Orthopaedic Translation - July 27, 2018 Category: Orthopaedics Source Type: research