Dietary Nitrate Intake Is Positively Associated with Muscle Function in Men and Women Independent of Physical Activity Levels
ConclusionsHigher habitual dietary nitrate intake, predominantly from vegetables, could be an effective way to promote lower-limb muscle strength and physical function in men and women. (Source: Journal of Nutrition)
Source: Journal of Nutrition - March 24, 2021 Category: Nutrition Source Type: research

Gut Reaction: Habitual Dietary Nitrate Intake as a Modulator of Skeletal Muscle Contractile Function
See corresponding article onpage 1222. (Source: Journal of Nutrition)
Source: Journal of Nutrition - March 24, 2021 Category: Nutrition Source Type: research

Maternal First-Trimester Cow-Milk Intake Is Positively Associated with Childhood General and Abdominal Visceral Fat Mass and Lean Mass but Not with Other Cardiometabolic Risk Factors at the Age of 10 Years
ConclusionsOur results suggest that maternal first-trimester milk intake is positively associated with childhood general and abdominal visceral fat mass and lean mass, but not with other cardiometabolic risk factors. (Source: Journal of Nutrition)
Source: Journal of Nutrition - March 23, 2021 Category: Nutrition Source Type: research

Genetics of Iron Metabolism and Premenstrual Symptoms: A Mendelian Randomization Study
ConclusionsThis Mendelian randomization study demonstrates that women with an elevated risk of iron overload may have a lower risk of experiencing some premenstrual symptoms (headache, confusion, and nausea), suggesting that iron status could impact the risk of certain premenstrual symptoms. (Source: Journal of Nutrition)
Source: Journal of Nutrition - March 23, 2021 Category: Nutrition Source Type: research

Postprandial Fatty Acid Profile, but Not Cardiometabolic Risk Markers, Is Modulated by Dairy Fat Manipulation in Adults with Moderate Cardiovascular Disease Risk: The Randomized Controlled REplacement of SaturatEd fat in dairy on Total cholesterol (RESET) Study
ConclusionsIn adults at moderate cardiovascular risk, acute consumption of sequential high-fat meals containing FA-modified dairy products had little impact on postprandial endothelial function or systemic cardiometabolic biomarkers, but a differential effect on the plasma total lipid FA profile, relative to conventional dairy fat meals.This trial was registered atclinicaltrials.gov as NCT02089035. (Source: Journal of Nutrition)
Source: Journal of Nutrition - March 23, 2021 Category: Nutrition Source Type: research

Associations of Early Pregnancy and Neonatal Circulating Folate, Vitamin B-12, and Homocysteine Concentrations with Cardiometabolic Risk Factors in Children at 10 y of Age
ConclusionsSubtle differences in circulating folate and vitamin B-12 concentrations in early pregnancy may be associated with child cardiometabolic health at age 10 y. The causality and mechanisms underlying these associations need further study. (Source: Journal of Nutrition)
Source: Journal of Nutrition - March 23, 2021 Category: Nutrition Source Type: research

Strawberry Consumption, Cardiometabolic Risk Factors, and Vascular Function: A Randomized Controlled Trial in Adults with Moderate Hypercholesterolemia
ConclusionStrawberries may improve vascular health, independent of other metabolic changes. The effect may be related to changes in microbial-derived phenolic metabolites after strawberry consumption influencing endothelial function. Data support inclusion of strawberries in a heart-healthy diet in adults with moderate hypercholesterolemia.This trial was registered at clinicaltrials.gov as NCT02612090. (Source: Journal of Nutrition)
Source: Journal of Nutrition - March 23, 2021 Category: Nutrition Source Type: research

Associations of Intake of Free and Naturally Occurring Sugars from Solid Foods and Drinks with Cardiometabolic Risk Factors in a Quebec Adult Population: The PREDISE (PR ÉDicteurs Individuels, Sociaux et Environnementaux) Study
ConclusionsOur data from an adult sample showed that unfavorable and favorable associations with cardiometabolic risk factors observed, respectively, for FS intake from drinks and NOS intake from foods are mostly explained by sociodemographic and lifestyle variables, as well as by diet quality. (Source: Journal of Nutrition)
Source: Journal of Nutrition - March 23, 2021 Category: Nutrition Source Type: research

Letrozole-Induced Polycystic Ovary Syndrome Attenuates Cystathionine- β Synthase mRNA and Protein Abundance in the Ovaries of Female Sprague Dawley Rats
ConclusionThese data demonstrate that letrozole-induced PCOS Sprague Dawley rats temporally decrease the ovarian abundance ofCbs mRNA and protein in the early stages of PCOS. (Source: Journal of Nutrition)
Source: Journal of Nutrition - March 23, 2021 Category: Nutrition Source Type: research

A School-Based Weekly Iron and Folic Acid Supplementation Program Effectively Reduces Anemia in a Prospective Cohort of Ghanaian Adolescent Girls
ConclusionsSchool-based weekly IFA supplementation is effective in improving Hb and reducing the anemia prevalence among schoolgirls in Ghana, though most participants consumed fewer than the minimum effective number of IFA tablets. Increasing intake adherence may further improve anemia outcomes in this population. (Source: Journal of Nutrition)
Source: Journal of Nutrition - March 23, 2021 Category: Nutrition Source Type: research

Consumption of a Variety of Vegetables to Meet Dietary Guidelines for Americans ’ Recommendations Does Not Induce Sensitization of Vegetable Reinforcement Among Adults with Overweight and Obesity: A Randomized Controlled Trial
ConclusionsThese findings suggest no effects of the provision of a variety of vegetables to meet DGA recommendations for 8 weeks on vegetable reinforcement and highlight the difficulty in increasing vegetable consumption in adults. This trial was registered atclinicaltrials.gov as NCT02585102. (Source: Journal of Nutrition)
Source: Journal of Nutrition - March 23, 2021 Category: Nutrition Source Type: research

Determination of Vitamin A Total Body Stores in Children from Dried Serum Spots: Application in a Low- and Middle-Income Country Community Setting
ConclusionsVA TBS can be determined from DSS thereby reducing the logistics and cost of maintaining a cold chain by shipping samples at ambient temperature and, thus, making the RID technique more feasible in LMIC community settings. This trial was registered athttps://clinicaltrials.gov as NCT03030339. (Source: Journal of Nutrition)
Source: Journal of Nutrition - March 23, 2021 Category: Nutrition Source Type: research

Calcium Intake and Iron Status in Human Studies: A Systematic Review and Dose-Response Meta-Analysis of Randomized Trials and Crossover Studies
ConclusionsThe  existing body of studies is insufficient to make recommendations with high confidence due to heterogeneity in designs, limitations of ferritin as an iron biomarker, and a lack of intake studies in pregnant women. Prescribing separation of prenatal calcium and iron supplements in free-living indivi duals is unlikely to affect the anemia burden. There is a need for effectiveness trials comparing the effects of prescribing separated intake to concurrent intake, with functional endpoints as primary outcomes and adherence to each supplement as intermediate outcomes. (Source: Journal of Nutrition)
Source: Journal of Nutrition - March 23, 2021 Category: Nutrition Source Type: research

Evening Chronotype Is Associated with Poorer Habitual Diet in US Women, with Dietary Energy Density Mediating a Relation of Chronotype with Cardiovascular Health
ConclusionsEvening chronotype could contribute to unhealthful dietary patterns in US women, with higher dietary ED partially mediating the relation between eveningness and poorer CVH. Behavioral interventions to reduce dietary ED might mitigate cardiovascular disease risk in women with evening chronotype. (Source: Journal of Nutrition)
Source: Journal of Nutrition - March 23, 2021 Category: Nutrition Source Type: research

A Helpful Reminder of BMI's Nuances but Little Support for the “Obesity Paradox”
See corresponding article onpage 1213. (Source: Journal of Nutrition)
Source: Journal of Nutrition - March 23, 2021 Category: Nutrition Source Type: research