Pyruvate Kinase M2 Supports Muscle Progenitor Cell Proliferation but Is Dispensable for Skeletal Muscle Regeneration after Injury
ConclusionsThe results suggest that the noncanonical activity of PKM2 is important for MPC proliferation in vitro and demonstrate GLUD1 as a PKM2 binding partner. Because no impairments in muscle regeneration were detected in a mouse model, the endogenous environment may compensate for loss of PKM2. (Source: Journal of Nutrition)
Source: Journal of Nutrition - August 12, 2021 Category: Nutrition Source Type: research
Omega-3 Fatty Acid Dietary Supplements Consumed During Pregnancy and Lactation and Child Neurodevelopment: A Systematic Review
ConclusionsLimited evidence suggests that omega-3 fatty acid supplementation during pregnancy may result in favorable cognitive development in the child. There was insufficient evidence to evaluate the effects of omega-3 fatty acid supplementation during pregnancy and/or lactation on other developmental outcomes. (Source: Journal of Nutrition)
Source: Journal of Nutrition - August 12, 2021 Category: Nutrition Source Type: research
Lactobacillus johnsonii Attenuates Citrobacter rodentium –Induced Colitis by Regulating Inflammatory Responses and Endoplasmic Reticulum Stress in Mice
ConclusionsL. johnsonii supplementation is a promising nutritional strategy for preventingC. rodentium–induced colitis in mice. (Source: Journal of Nutrition)
Source: Journal of Nutrition - August 12, 2021 Category: Nutrition Source Type: research
Physiological Limitations of Protein Foods Ounce Equivalents and the Underappreciated Role of Essential Amino Acid Density in Healthy Dietary Patterns
ABSTRACTProtein quality is an important component of protein intake to support growth, development, and maintenance of essential body tissues and functions. Therefore, protein quality should be emphasized as a key characteristic during protein food selection within the larger context of healthy dietary patterns, especially when considering the wide variance of protein quality across animal- and plant-based foods. However, the USDA Dietary Guidelines for Americans (DGA) do not address specific protein quality recommendations within their protein foods ounce equivalents guidance or as a component of Healthy U.S. Style, Healt...
Source: Journal of Nutrition - August 12, 2021 Category: Nutrition Source Type: research
Use of the Electronic Health Record to Assess Prevalence of Anemia and Iron Deficiency in Pregnancy
ConclusionsEHR data have potential to monitor anemia prevalence and trends in health systems where prenatal anemia screening is nearly universal. However, if iron assessment is not routine, then representative estimates of ID or IDA are unattainable. (Source: Journal of Nutrition)
Source: Journal of Nutrition - August 12, 2021 Category: Nutrition Source Type: research
Increasing Vegetable Intake Decreases Urinary Acidity and Bone Resorption Marker in Overweight and Obese Adults: An 8-Week Randomized Controlled Trial
ConclusionsConsumption of vegetables at the DGA-recommended amount by adults with low vegetable intake potentially benefits bone health. This trial was registered atclinicaltrials.gov as NCT02585102. (Source: Journal of Nutrition)
Source: Journal of Nutrition - August 12, 2021 Category: Nutrition Source Type: research
Dietary Intake of Breastfeeding Mothers in Developed Countries: A Systematic Review and Results of the MEDIDIET Study
ConclusionsThis SR showed that nutrient intakes of breastfeeding mothers in developed countries are generally in line with DRVs despite different dietary patterns worldwide. Some nutritional deficiencies emerged, highlighting the need for additional nutritional advice. Mothers participating in the MEDIDIET study showed a nutritional profile in agreement with the Mediterranean diet. (Source: Journal of Nutrition)
Source: Journal of Nutrition - August 12, 2021 Category: Nutrition Source Type: research
A 10% Tomato Diet Selectively Reduces Radiation-Induced Damage in TRAMP Mice
ConclusionsTP selectively reduces radiation-induced apoptosis in extratumoral tissues without decreasing radiation-induced apoptosis within the prostate tumor in TRAMP mice. Additional studies are needed to confirm and expand upon these findings. (Source: Journal of Nutrition)
Source: Journal of Nutrition - August 12, 2021 Category: Nutrition Source Type: research
Gut Microbiome Diversity and Composition Are Associated with Habitual Dairy Intakes: A Cross-Sectional Study in Men
ConclusionsIn men, community-level microbiome differences were observed between consumers and nonconsumers of milk and yogurt. Bacterial taxon-level associations were detected with milk, yogurt, and cheese consumption. Total dairy consumption was not associated with any microbiome measures, suggesting that individual dairy foods may have differential roles in shaping the gut microbiome in men. (Source: Journal of Nutrition)
Source: Journal of Nutrition - August 12, 2021 Category: Nutrition Source Type: research
Nutrient Adequacy Is Associated with Reduced Mortality in US Adults
ConclusionsThese findings suggest that higher intakes of underconsumed nutrients and improving macronutrient quality are associated with lower risk of CVD and cancer deaths in US adults. (Source: Journal of Nutrition)
Source: Journal of Nutrition - August 12, 2021 Category: Nutrition Source Type: research
Adolescent Plant Product Intake in Relation to Later Prostate Cancer Risk and Mortality in the NIH-AARP Diet and Health Study
ConclusionsOur findings do not provide strong evidence to suggest that adolescent plant product intake is associated with reduced PCa risk. (Source: Journal of Nutrition)
Source: Journal of Nutrition - August 12, 2021 Category: Nutrition Source Type: research
Water Intake and Markers of Hydration Are Related to Cardiometabolic Risk Biomarkers in Community-Dwelling Older Adults: A Cross-Sectional Analysis
ConclusionsOur findings of a consistent pattern between circulating lipid concentrations and different water sources and hydration markers support an association between hydration and lipid metabolism in older adults and add to the growing evidence that inadequate water intake and underhydration may lead to higher cardiometabolic risk. (Source: Journal of Nutrition)
Source: Journal of Nutrition - August 12, 2021 Category: Nutrition Source Type: research
Pecan-Enriched Diets Alter Cholesterol Profiles and Triglycerides in Adults at Risk for Cardiovascular Disease in a Randomized, Controlled Trial
ConclusionsPecan consumption improves fasting and postprandial blood lipids in CVD at-risk adults. This trial was registered at clinicaltrials.gov as NCT04376632. (Source: Journal of Nutrition)
Source: Journal of Nutrition - August 12, 2021 Category: Nutrition Source Type: research
Reduced Shmt2 Expression Impairs Mitochondrial Folate Accumulation and Respiration, and Leads to Uracil Accumulation in Mouse Mitochondrial DNA
ConclusionsThis study demonstrates thatShmt2 heterozygosity and dietary folate deficiency impair mitochondrial dTMP synthesis in mice, as evidenced by the increased uracil in mtDNA. In addition,Shmt2 heterozygosity impairs mitochondrial function in MEF cells. These findings suggest that elevated uracil in mtDNA may impair mitochondrial function. (Source: Journal of Nutrition)
Source: Journal of Nutrition - August 12, 2021 Category: Nutrition Source Type: research
Dietary Nucleotides Alleviate Hepatic Lipid Deposition via Exogenous AMP-Mediated AMPK Activation in Zebrafish
ConclusionsDietary NTs and AMP reduce hepatic lipid deposition in zebrafish, which involves exogenous AMP-mediated AMPK activation. Our results suggest that dietary NTs can contribute to alleviation of hepatic steatosis. (Source: Journal of Nutrition)
Source: Journal of Nutrition - August 12, 2021 Category: Nutrition Source Type: research
