Effects of vitamin C local application on ligature-induced periodontitis in diabetic rats
Conclusion: This study reveals that vitamin C treatment may be beneficial to reduce serum CTX and gingival MMP-8 levels, oxidative stress, inflammation, and AGE accumulation in periodontal tissue. Vitamin C may be an immunomodulator and antioxidant locally applied in the treatment of periodontitis to reduce the adverse effects of diabetes in periodontal tissues. (Source: Journal of Applied Oral Science)
Source: Journal of Applied Oral Science - November 28, 2020 Category: Dentistry Source Type: research
Latent TGF-beta binding protein-1 plays an important role in craniofacial development
Conclusions: Our experiments found that ltbp1 was expressed in zebrafish mandibular jaw cartilages and the surrounding muscles. The ltbp1 knockdown zebrafish exhibited phenotypes consistent with Ltbp1 knockout mice. And loss of ltbp1 function lead to significant mandibular jaw defects and affect both jaw cartilages and surrounding muscles. (Source: Journal of Applied Oral Science)
Source: Journal of Applied Oral Science - November 28, 2020 Category: Dentistry Source Type: research
Effect of different surface treatments and multimode adhesive application on the Weibull characteristics, wettability, surface topography and adhesion to CAD/CAM lithium disilicate ceramic
Conclusion: The HF 20s, 60s, 120 s followed by silane, promoted sim ilar resin-bond strength to ceramic and the SBU application after HF or MEP did not increase the SBS. (Source: Journal of Applied Oral Science)
Source: Journal of Applied Oral Science - November 28, 2020 Category: Dentistry Source Type: research
One-year evaluation of a new restorative glass ionomer cement for the restoration of non-carious cervical lesions in patients with systemic diseases: a randomized, clinical trial
Conclusion Although the posterior resin composite demonstrated clinically higher alpha scores than the conventional GIC for marginal adaptation and discoloration, both materials successfully restored NCCLs at patients with systematic disease after a year. Clinical relevance Due to its acceptable clinical results, the tested conventional restorative GIC can be used for the restoration of NCCLs of patients with systemic diseases. (Source: Journal of Applied Oral Science)
Source: Journal of Applied Oral Science - October 23, 2020 Category: Dentistry Source Type: research
Transcriptome profile of highly osteoblastic/cementoblastic periodontal ligament cell clones
Conclusions This comprehensive transcriptomic assessment of human PDL progenitor cells revealed that expression of transcripts related to the biological process “ anatomical structure development, ” Cadherin signaling, and Wnt signaling can identify PDL cells with a higher potential to commit to the O/C phenotype. A better understanding of these pathways and their function in O/C differentiation will help to improve protocols for periodontal regenerative therapies. (Source: Journal of Applied Oral Science)
Source: Journal of Applied Oral Science - October 23, 2020 Category: Dentistry Source Type: research
Influence of the height of the mandibular ridge on the masticatory function during the functional adaptation with new complete dentures
Conclusions The study suggests that the participants with NR have higher MP and satisfaction with their CD, regardless of the follow-up period after the insertion of the new CD. After subjects received the CD, a period of 3 months was necessary for achieving better achievement MOBF, MP, and self-perceived comfort with the mandibular denture, regardless of the height of the mandibular ridge. (Source: Journal of Applied Oral Science)
Source: Journal of Applied Oral Science - October 23, 2020 Category: Dentistry Source Type: research
In situ effect of a proanthocyanidin mouthrinse on dentin subjected to erosion
Conclusion The 10% proanthocyanidin mouthrinse (pH 7.0) could be a good stra tegy to reduce dentin wear progression. (Source: Journal of Applied Oral Science)
Source: Journal of Applied Oral Science - October 23, 2020 Category: Dentistry Source Type: research
Effects of different toothpastes on the prevention of erosion in composite resin and glass ionomer cement enamel and dentin restorations
Conclusions NaF-based toothpastes had no protective effect on enamel adjacent to CR and RMGIC against erosion-abrasion challenges, nor on dentin adjacent to RMGIC material. SnF2-based toothpastes caused more damage to interfaces between enamel and RMGIC. (Source: Journal of Applied Oral Science)
Source: Journal of Applied Oral Science - September 28, 2020 Category: Dentistry Source Type: research
Effect of glazing application side and mechanical cycling on the biaxial flexural strength and Weibull characteristics of a Y-TZP ceramic
Conclusion Glazing zirconia applied on both tensile and compression sides improves the flexural strength of Y-TZP, regardless the mechanical aging. (Source: Journal of Applied Oral Science)
Source: Journal of Applied Oral Science - September 28, 2020 Category: Dentistry Source Type: research
Gingival inflammation, enamel defects, and tooth sensitivity in children with amelogenesis imperfecta: a case-control study
Conclusion Gingival inflammation, enamel defect and tooth sensitivity are more frequently observed among young patients with amelogenesis imperfecta, and more specifically among children with the hypocalcified subtype. (Source: Journal of Applied Oral Science)
Source: Journal of Applied Oral Science - September 28, 2020 Category: Dentistry Source Type: research
Increase in serum and salivary neutrophil gelatinase-associated lipocalin levels with increased periodontal inflammation
Conclusion: The overlapping PISA values found in Groups 2 and 3 suggest that gingivitis might progress to a systemic inflammatory burden somewhat comparable to stage I periodontitis. This finding is supported by the higher serum and salivary cytokines/mediators levels in the gingivitis group than in stage I periodontitis group. Serum and salivary NGAL levels increased proportionally to disease severity and PISA. NGAL seems to play a role in the pathogenesis of periodontal disease, within the limitation of our study. (Source: Journal of Applied Oral Science)
Source: Journal of Applied Oral Science - September 28, 2020 Category: Dentistry Source Type: research
Biomechanical and morphological changes produced by ionizing radiation on bone tissue surrounding dental implant
Conclusion: Ionizing radiation in dental implants resulted in negative effects on the microarchitecture and biomechanical properties of bone tissue, mainly near the surface of the implant. (Source: Journal of Applied Oral Science)
Source: Journal of Applied Oral Science - September 28, 2020 Category: Dentistry Source Type: research
COVID-19: Perspectives for the management of dental care and education
Abstract The rapid and abrupt transmission pattern of the SARS-CoV-2 unleashed the current COVID-19 pandemic, as recognized by the World Health Organization in March 2020. Considering the high risk of transmission of the virus in dental environments and the specificities in clinical practice, COVID-19 posed immediate challenges for dental care and education. Due to the need to establish infection prevention and control guidance in dental health settings to enable a safe clinical practice, this review aims to list the challenges and perspectives in managing dental care in services and schools. This review employed materials...
Source: Journal of Applied Oral Science - September 28, 2020 Category: Dentistry Source Type: research
Treatment outcomes of pulp revascularization in traumatized immature teeth using calcium hydroxide and 2% chlorhexidine gel as intracanal medication
Conclusions Pulp revascularization in traumatized immature teeth treated with calcium hydroxide plus 2% chlorhexidine gel as intracanal medication had high success and survival rates, showing periodontal healing and resolution of signs and symptoms. However, concerning the continued root development, the outcomes can still be considered unpredictable. (Source: Journal of Applied Oral Science)
Source: Journal of Applied Oral Science - September 25, 2020 Category: Dentistry Source Type: research
Delayed alveolar bone repair and osteonecrosis associated with Zoledronic Acid therapy in rats: macroscopic, microscopic and molecular analysis
Conclusion The results highlighted strong and evident interference of zoledronic acid in bone repair of the socket, causing osteonecrosis and delayed bone remodeling. (Source: Journal of Applied Oral Science)
Source: Journal of Applied Oral Science - September 25, 2020 Category: Dentistry Source Type: research
