Frequency of Porphyromonas gingivalis fimA in smokers and nonsmokers after periodontal therapy
Conclusion The most prevalent P. gingivalis fimA genotypes detected in periodontal and smoker patients were genotypes I and II. However, the presence of fimA genotype II was higher in SM. Periodontal treatment was effective in controlling periodontal disease and reducing type II and V P. gingivalis fimA. (Source: Journal of Applied Oral Science)
Source: Journal of Applied Oral Science - April 12, 2019 Category: Dentistry Source Type: research

The influence of Aloe vera with mesenchymal stem cells from dental pulp on bone regeneration: characterization and treatment of non-critical defects of the tibia in rats
Conclusion The results suggest that the combination of Hemospon®, Aloe vera and hDPSCs is a form of clinical treatment for the repair of non-critical bone defects that reduces the inflammatory cascade ’ s effects. (Source: Journal of Applied Oral Science)
Source: Journal of Applied Oral Science - April 12, 2019 Category: Dentistry Source Type: research

Erratum: Temporomandibular joint disc displacement with reduction: a review of mechanisms and clinical presentation
Conclusions It was not possible to compare the results for the mechanical and optical properties of conventional restorative GICs due to the lack of standardization of studies. (Source: Journal of Applied Oral Science)
Source: Journal of Applied Oral Science - April 1, 2019 Category: Dentistry Source Type: research

Addition of zirconium oxide to Biodentine increases radiopacity and does not alter its physicochemical and biological properties
Conclusions: Addition of 15% ZrO2 or CaWO4 was sufficient to increase the radiopacity of BD to values higher than 3 mm Al. BD associated with radiopacifiers showed suitable properties of setting time, pH and solubility, except for BDCaWO4, which showed the highest solubility. All cements had cytocompatibility and potential to induce mineralization in Saos-2 cells. The results showed that adding 15% ZrO2 increases the radiopacity of BD, allowing its radiography detection without altering its physicochemical and biological properties. (Source: Journal of Applied Oral Science)
Source: Journal of Applied Oral Science - April 1, 2019 Category: Dentistry Source Type: research

Diversity of clinical, radiographic and genealogical findings in 41 families with amelogenesis imperfecta
Conclusion: Of the five clinical subtypes, autosomal recessive hypomature, autosomal dominant hypoplastic and autosomal recessive hypomature/hypoplastic AI were the most prevalent subtypes in this group. (Source: Journal of Applied Oral Science)
Source: Journal of Applied Oral Science - April 1, 2019 Category: Dentistry Source Type: research

A new technique for tongue brushing and halitosis reduction: the X technique
Conclusion: These results indicate that the X technique improves both measurements and perceptions of halitosis. Microbiological analyses revealed greatest reduction in the 6R group. The findings show that the X technique reduces both organoleptic scores and the number of bacterial colonies, and improves users ’ perceptions of their breath. (Source: Journal of Applied Oral Science)
Source: Journal of Applied Oral Science - April 1, 2019 Category: Dentistry Source Type: research

Difference of brain-derived neurotrophic factor expression and pyramid cell count during mastication of food with varying hardness
Conclusion: A standard diet leads to the optimum effect on hippocampus morphology. Food consistency must be appropriately suited to each development stage, in this case, hippocampus development in post-weaned period. (Source: Journal of Applied Oral Science)
Source: Journal of Applied Oral Science - April 1, 2019 Category: Dentistry Source Type: research

Mechanical and optical properties of conventional restorative glass-ionomer cements - a systematic review
Conclusions It was not possible to compare the results for the mechanical and optical properties of conventional restorative GICs due to the lack of standardization of studies. (Source: Journal of Applied Oral Science)
Source: Journal of Applied Oral Science - February 21, 2019 Category: Dentistry Source Type: research

Temporomandibular joint disc displacement with reduction: a review of mechanisms and clinical presentation
Abstract Disc displacement with reduction (DDWR) is one of the most common intra-articular disorders of the temporomandibular joint (TMJ). Factors related to the etiology, progression and treatment of such condition is still a subject of discussion. This literature review aimed to address etiology, development, related factors, diagnosis, natural course, and treatment of DDWR. A non-systematic search was conducted within PubMed, Scopus, SciELO, Medline, LILACS and Science Direct using the Medical Subjective Headings (MeSH) terms “ temporomandibular disorders ” , “ temporomandibular joint ” , “ disc displacement ...
Source: Journal of Applied Oral Science - February 21, 2019 Category: Dentistry Source Type: research

Retinoic acid increases the effect of bone morphogenetic protein type 2 on osteogenic differentiation of human adipose-derived stem cells
Abstract Bone morphogenetic protein type 2 (BMP-2) and retinoic acid (RA) are osteoinductive factors that stimulate endogenous mechanisms of bone repair which can be applied on management of osseous defects in oral and maxillofacial fields. Objective Considering the different results of RA on osteogenesis and its possible use to substitute/potency BMP-2 effects, this study evaluated the outcomes of BMP-2, RA, and BMP-2+RA treatments on in vitro osteogenic differentiation of human adipose-derived stem cells (ASCs) and the signaling pathway(s) involved. Material and Methods ASCs were treated every other day with basic os...
Source: Journal of Applied Oral Science - February 21, 2019 Category: Dentistry Source Type: research

Periodontal disease, peri-implant disease and levels of salivary biomarkers IL-1β, IL-10, RANK, OPG, MMP-2, TGF-β and TNF-α: follow-up over 5 years
Conclusions The salivary concentration of TNF- α was increased in individuals with worse periodontal and peri-implant clinical condition and in those with a higher incidence of peri-implantitis, especially in the GNTP group. Longitudinal studies in larger populations are needed to confirm these findings and elucidate the role of this biomarker in peri-implant disease. (Source: Journal of Applied Oral Science)
Source: Journal of Applied Oral Science - February 21, 2019 Category: Dentistry Source Type: research

Cytotoxicity of intracanal dressings on apical papilla cells differ upon activation with E. faecalis LTA
Conclusion mTAP showed higher cytotoxicity than CMC and mCMC and the effect of topic antimicrobials might differ when tested against apical papilla cells under physiological or activated conditions. (Source: Journal of Applied Oral Science)
Source: Journal of Applied Oral Science - February 21, 2019 Category: Dentistry Source Type: research

Fluoride release and uptake in enhanced bioactivity glass ionomer cement (“glass carbomer™”) compared with conventional and resin-modified glass ionomer cements
Conclusions Glass carbomer resembles glass ionomer cements in its fluoride uptake behavior but differs when considering that its fluoride uptake does not lead to increased fluoride release. (Source: Journal of Applied Oral Science)
Source: Journal of Applied Oral Science - February 21, 2019 Category: Dentistry Source Type: research

Gliclazide reduced oxidative stress, inflammation, and bone loss in an experimental periodontal disease model
Conclusions This treatment decreased neutrophil and macrophage migration, decreased the inflammatory response, and decreased bone loss in rats with ligature-induced periodontitis. (Source: Journal of Applied Oral Science)
Source: Journal of Applied Oral Science - February 21, 2019 Category: Dentistry Source Type: research

Resin-modified glass ionomer containing calcium glycerophosphate: physico-mechanical properties and enamel demineralization
Conclusion The addition of 3% CaGP in RMGIC increased the release of F, P and Ca, reduced enamel demineralization, and maintained the physico-mechanical properties within the parameters for this material. (Source: Journal of Applied Oral Science)
Source: Journal of Applied Oral Science - February 21, 2019 Category: Dentistry Source Type: research