Transcriptome profile of highly osteoblastic/cementoblastic periodontal ligament cell clones

Conclusions This comprehensive transcriptomic assessment of human PDL progenitor cells revealed that expression of transcripts related to the biological process “ anatomical structure development, ” Cadherin signaling, and Wnt signaling can identify PDL cells with a higher potential to commit to the O/C phenotype. A better understanding of these pathways and their function in O/C differentiation will help to improve protocols for periodontal regenerative therapies.
Source: Journal of Applied Oral Science - Category: Dentistry Source Type: research