Effects of vitamin C local application on ligature-induced periodontitis in diabetic rats

Conclusion: This study reveals that vitamin C treatment may be beneficial to reduce serum CTX and gingival MMP-8 levels, oxidative stress, inflammation, and AGE accumulation in periodontal tissue. Vitamin C may be an immunomodulator and antioxidant locally applied in the treatment of periodontitis to reduce the adverse effects of diabetes in periodontal tissues.
Source: Journal of Applied Oral Science - Category: Dentistry Source Type: research