High thermal stability and low power dissipation PCM with nanoscale oxygen-doped SS thin film
To improve thermal stability and reduce power dissipation of phase-change memory (PCM), the oxygen-doped Sn15Sb85 (SS) thin film is proposed by magnetron sputtering in this study. Comparing to undoped Sn15Sb85(SS), the oxygen-doped-SS thin film has superior thermal stability and better data retention. Meanwhile, the electrical conductivity of crystallisation oxygen-doped-SS thin film is also lower than that of SS, which means its less power consuming in PCM. The electrical conductivity ratio between amorphous and crystalline states for oxygen-doped SS reaches up to two orders of magnitude. After oxygen doping, the root-mea...
Source: IET Nanobiotechnology - December 7, 2018 Category: Nanotechnology Source Type: research
Design and fabrication of drug-eluting polymeric thin films for applications in ophthalmology
To study the development, characterisation, and drug release of one- and two-layered thin films based on organic polymers [poly(D,L-lactide-co-glycolide) lactide:glycolide (65:35), poly(D,L-lactide-co-glycolide) lactide:glycolide (75:25), and polycaprolactone] and dexamethasone. To examine their applicability for intraocular lenses (IOLs) and function in intraocular drug delivery systems. Four series of thin films, single and double-layer, were prepared by the spin-coating method on a silicon substrate. The films were studied using atomic force microscopy and spectroscopic ellipsometry. The release rate of dexamethasone wa...
Source: IET Nanobiotechnology - December 7, 2018 Category: Nanotechnology Source Type: research
Comparative antileishmanial efficacy of the biosynthesised ZnO NPs from genus Verbena
This study describes ZnO NPs biosynthesis using leaf extracts of Verbena officinalis and Verbena tenuisecta. The extracts serve as natural reducing, capping and stabilization facilitators. Plant extracts phytochemical analysis, revealed that V. officinalis showed higher total phenolic and flavonoid content (22.12 and 6.38 mg g −1 DW) as compared to V. tennuisecta (12.18 and 2.7 mg g −1 DW). ZnO NPs were characterised by ultraviolet–visible spectroscopy, Fourier transform infrared, X-ray diffraction, scanning electron microscope, transmission electron microscopy (TEM) and energy dispersive X-ray. TEM an...
Source: IET Nanobiotechnology - December 7, 2018 Category: Nanotechnology Source Type: research
Investigative evaluation of Cassia absus for antibacterial capacity and biomimetic synthesis of silver nanoparticles
In this study, the authors report the antimicrobial potential of C. absus extracts obtained with different solvents. The extract(s) obtained with ethyl acetate yielded the best antibacterial effects because of a rich supply of oxalates and alkaloids in it. The same extract was also exploited for reducing Ag+ ions (to metallic Ag0) for the synthesis of nanoparticles. Electron microscopy revealed that the silver nanoparticles were ∼18–25 nm in diameter. The Fourier-transform infrared evaluation pointed towards the fact that flavonoids present in the plant extract were acting as reductants while amino gro...
Source: IET Nanobiotechnology - December 7, 2018 Category: Nanotechnology Source Type: research
Ferulic acid encapsulated chitosan-tripolyphosphate nanoparticles attenuate quorum sensing regulated virulence and biofilm formation in Pseudomonas aeruginosa PAO1
In this study, the anti-quorum sensing and anti-biofilm potential of ferulic acid encapsulated chitosan-tripolyphosphate nanoparticles (FANPs) was investigated against P. aeruginosa PAO1 and compared with native ferulic acid. Dynamic light scattering and transmission electron microscopic analysis confirmed the synthesis of FANPs with mean diameter of 215.55 nm. FANPs showed significant anti-quorum sensing activity by downregulating QS-regulated virulence factors. In addition, FANPs also significantly attenuate the swimming and swarming motility of P. aeruginosa PAO1. The anti-biofilm efficacy of FANPs as compared to...
Source: IET Nanobiotechnology - December 7, 2018 Category: Nanotechnology Source Type: research
Biogenic synthesis of biopolymer-based Ag–Au bimetallic nanoparticle constructs and their anti-proliferative assessment
This study reports an eco-friendly-based method for the preparation of biopolymer Ag–Au nanoparticles (NPs) by using gum kondagogu (GK; Cochlospermum gossypium), as both reducing and protecting agent. The formation of GK-(Ag–Au) NPs was confirmed by UV-absorption, fourier transformed infrared (FTIR), atomic force microscopy (AFM), scanning electron microscope (SEM) and transmission electron microscope (TEM). The GK-(Ag–Au) NPs were of 1–12 nm in size. The anti-proliferative activity of nanoparticle constructs was assessed by MTT assay, confocal microscopy, flow cytometry and quantitative ...
Source: IET Nanobiotechnology - December 7, 2018 Category: Nanotechnology Source Type: research
Green synthesis of copper oxide nanoparticles and mosquito larvicidal activity against dengue, zika and chikungunya causing vector Aedes aegypti
In the present study, high purity copper oxide nanoparticles (NPs) were synthesised using Tridax procumbens leaf extract. Green syntheses of nano-mosquitocides rely on plant compounds as reducing and stabilising agents. Copper oxide NPs were characterised using X-ray diffraction (XRD) analysis, Fourier transform infrared (FT-IR), Field-emission scanning electron microscopy with energy dispersive spectroscopy, Ultraviolet–visible spectrophotometry and fluorescence spectroscopy. XRD studies of the NPs indicate crystalline nature which was perfectly matching with a monoclinic structure of bulk CuO with an average cryst...
Source: IET Nanobiotechnology - December 7, 2018 Category: Nanotechnology Source Type: research
DOC-LS, a new liposome for dermal delivery, and its endocytosis by HaCaT and CCC-ESF-1 cells
This study provides a basis for the application of LS being combined with a microneedle system for efficient intracellular drug delivery, targeting cutaneous histocyte disorders. (Source: IET Nanobiotechnology)
Source: IET Nanobiotechnology - December 7, 2018 Category: Nanotechnology Source Type: research
Bio-synthesis of palladium nanocubes and their electrocatalytic properties
This study reveals the possibility of preparing shape-controlled PdNCs with a specific structure and excellent electro-catalytic activity. (Source: IET Nanobiotechnology)
Source: IET Nanobiotechnology - December 7, 2018 Category: Nanotechnology Source Type: research
How nano-wollastonite can change the fundamental properties of a wood fibre and rice straw composites?
The potential of using rice straw (RS) in combination with wood fibre in the production of medium density fibreboard was investigated. Nano-wollastonite (NW) was added to some of the panels to determine if it would enhance the physical and mechanical properties. It was found that satisfactory composite boards could be made with the addition of 10% RS to the wood fibre. Furthermore, the mechanical and physical properties of the composite were enhanced when NW was added. (Source: IET Nanobiotechnology)
Source: IET Nanobiotechnology - December 7, 2018 Category: Nanotechnology Source Type: research
Nigella sativa oil entrapped polycaprolactone nanoparticles for leishmaniasis treatment
This study is the first to investigate the antileishmanial activities of Nigella sativa oil (NSO) entrapped poly-ɛ-caprolactone (PCL) nanoparticles on Leishmania infantum promastigotes and amastigotes in vitro. NSO molecules with variable initial doses of 50, 100, 150, and 200 mg were successfully encapsulated into PCL nanoparticles identified as formulations NSO1, NSO2, NSO3, and NSO4, respectively. This process was characterised by scanning electron microscope, dynamic light scattering, Fourier transform infrared, encapsulation efficiency measurements, and release profile evaluations. The resulting synthetis...
Source: IET Nanobiotechnology - December 7, 2018 Category: Nanotechnology Source Type: research
Nanomedicine for anticancer and antimicrobial treatment: an overview
Nanoparticle-based treatment has become a potential therapeutic approach. The nanosize of these particles provides them with unique physicochemical properties and enhances their interaction with the biological system. Nanomaterials have the potential to overcome some of the major issues in the clinical world which may include cancer treatment and may be utilised to resolve the major problem of drug resistance in infection control. These particles are being used to improve present therapeutics by virtue of their shape, size and diverse intrinsic as well as chemical properties. The authors have discussed the use of nanoparti...
Source: IET Nanobiotechnology - December 7, 2018 Category: Nanotechnology Source Type: research
Green synthesised iron and iron-based nanoparticle in environmental and biomedical application: – a review
Owing to the development of nanotechnology and its influence in various fields, the development of efficient and environmental friendly technique for the synthesis of nanomaterials is important. Among the various traditional and conventional methods available for the synthesis, plant-mediated synthesis seems to be a very attractive and environmental friendly method, attributing to its simple methodology and eco-friendly approach. The synthesis rate and stability of the nanoparticle synthesised are good when compared to the other methods of synthesis and it is proved to be efficient in various fields of application. Hence, ...
Source: IET Nanobiotechnology - December 7, 2018 Category: Nanotechnology Source Type: research
Silver nanoparticles biosynthesised using Centella asiatica leaf extract: apoptosis induction in MCF-7 breast cancer cell line
The aim of this study was to green synthesised silver nanoparticles (AgNPs) using Centella asiatica leaf extract and investigate the cytotoxic and apoptosis-inducing effects of these nanoparticles in MCF-7 breast cancer cell line. The characteristics and morphology of the green synthesised AgNPs were evaluated using transmission electron microscopy, scanning electron microscopy, UV-visible spectroscopy, X-ray diffraction, and Fourier-transform infrared spectroscopy. The MTT assay was used to investigate the anti-proliferative activity of biosynthesised nanoparticles in MCF-7 cells. Apoptosis test was performed using flow c...
Source: IET Nanobiotechnology - October 4, 2018 Category: Nanotechnology Source Type: research
In vivo biosynthesis and spatial distribution of Ag nanoparticles in maize (Zea mays L.)
This study presents direct evidence for synthesis of NPs and distribution of related nutrient elements in maize, which has great significance for studying synthetic application of NPs in crop plants. (Source: IET Nanobiotechnology)
Source: IET Nanobiotechnology - October 4, 2018 Category: Nanotechnology Source Type: research
