Decreased digit ratio (2D:4D) and gastric cancer in Chinese men
The development of finger length is influenced by the level of hormones during pregnancy in the womb. The relative length of 2nd to 4th digit (2D:4D) is considered as a putative marker for prenatal hormone exposure and may represent an individual susceptibility to certain diseases, particularly those hormone-related cancers (e.g., gastric cancer). (Source: Early Human Development)
Source: Early Human Development - August 23, 2016 Category: Perinatology & Neonatology Authors: Youjing Sheng, Wenli Qian, Lu Wang, Zhenghao Huo, Hong Lu, Haochen Yu, Zhi Geng, Ping Cheng Source Type: research

Gastrostomy tube placement in infants with congenital diaphragmatic hernia: Frequency, predictors, and growth outcomes
Gastrostomy tube (G-tube) placement is a common intervention for newborns with severe feeding difficulties. Infants with congenital diaphragmatic hernia (CDH) are at high risk for feeding problems. Prevalence of G-tube placement and consequent nutritional outcomes of infants with CDH and G-tubes has not been described. (Source: Early Human Development)
Source: Early Human Development - August 23, 2016 Category: Perinatology & Neonatology Authors: Sharmistha Rudra, Obinna O. Adibe, William F. Malcolm, P. Brian Smith, C. Michael Cotten, Rachel G. Greenberg Source Type: research

Validation of a culturally adapted developmental screening tool for Australian Aboriginal children: Early findings and next steps
Early detection of developmental problems is important for facilitating access to targeted intervention and maximising its positive effects. The later problems are identified, the more likely that they will become increasingly difficult to ameliorate. Standardised developmental screening tools are known to improve detection rates of developmental problems compared to clinical judgement alone and are widely recommended for use with all children. The Ages and Stages Questionnaire (ASQ-3) is a tool that is widely used in Australia. (Source: Early Human Development)
Source: Early Human Development - August 17, 2016 Category: Perinatology & Neonatology Authors: Samantha Simpson, Anita D ’Aprano, Collette Tayler, Siek Toon Khoo, Roxanne Highfold Source Type: research

Early developmental outcomes predicted by gestational age from 35 to 41weeks
Recent studies have indicated that children born only a few weeks earlier than their due date experience more health and cognitive problems than previously realized. (Source: Early Human Development)
Source: Early Human Development - August 14, 2016 Category: Perinatology & Neonatology Authors: Gwenden Dueker, Jing Chen, Candace Cowling, Brian Haskin Source Type: research

Movement Assessment of Infants and Alberta Infant Motor Scale prediction to Bayley-III outcome in extremely preterm infants
I commend Lefebvre et al. [1] for their study comparing 4-month infant assessments to 18-month outcomes on the Bayley Scales of Infant and Toddler Development (Bayley-III) [2]. Strengths of the Lefebvre study are inclusion of all subjects who met definition criteria, quantitative documentation of maternal and infant background characteristics, objective measures of outcomes, and clear analytic procedures. However, the authors' conclusion, “We cannot recommend routine clinical use of either the MAI or AIMS for the goal of prediction of later outcome” is undermined by the limitations of the study, which are not adequatel...
Source: Early Human Development - August 10, 2016 Category: Perinatology & Neonatology Authors: Marcia F. Williams Source Type: research

Analysis of sensory processing in preterm infants
Premature birth suggests condition of biological vulnerability, predisposing to neurological injuries, requiring hospitalization in Neonatal Intensive Care Units, which, while contributing to increase the survival rates, expose infants to sensory stimuli harmful to the immature organism. (Source: Early Human Development)
Source: Early Human Development - August 9, 2016 Category: Perinatology & Neonatology Authors: Thais Inven ção Cabral, Louise Gracelli Pereira da Silva, Cláudia Maria Simões Martinez, Eloisa Tudella Source Type: research

Learning disabilities among extremely preterm children without neurosensory impairment: Comorbidity, neuropsychological profiles and scholastic outcomes
Children born extremely preterm are at high risk for intellectual disability, learning disabilities, executive dysfunction and special educational needs, but little is understood about the comorbidity of intellectual and learning disabilities in this population. (Source: Early Human Development)
Source: Early Human Development - August 8, 2016 Category: Perinatology & Neonatology Authors: Samantha Johnson, Victoria Strauss, Camilla Gilmore, Julia Jaekel, Neil Marlow, Dieter Wolke Source Type: research

Vitamin D supplementation during pregnancy on infant anthropometric measurements and bone mass of mother-infant pairs: A randomized placebo clinical trial
Based on the essential role of vitamin D in the regulation of calcium metabolism, we evaluated the effects of 2000IUvitamin D/day in late pregnancy on infant's anthropometric measurements and bone mass parameters of mother-infant pairs. (Source: Early Human Development)
Source: Early Human Development - August 8, 2016 Category: Perinatology & Neonatology Authors: Farideh Vaziri, Mohammad Hossein Dabbaghmanesh, Alamtaj Samsami, Samira Nasiri, Pedram Talezadeh Shirazi Source Type: research

Minor neurological dysfunction in five year old very preterm children is associated with lower processing speed
Minor neurological dysfunction (MND) is present in one quarter to one third of children born very preterm (VP). The more severe form, complex (c)-MND has been associated with learning disabilities, behavioural and motor problems. (Source: Early Human Development)
Source: Early Human Development - August 7, 2016 Category: Perinatology & Neonatology Authors: Tinka Kurpershoek, Eva S. Potharst-Sirag, Cornelieke S.H. Aarnoudse-Moens, Aleid G. van Wassenaer-Leemhuis Source Type: research

Social reasoning abilities in preterm and full-term children aged 5 –7years
Literature has evidenced behavioral and socio-emotional problems in preterm children, as well as long-term difficulties to establish and maintain social relationships in preterm population. Several studies have shown relations between behavior and social reasoning abilities in typically developing children and adults. (Source: Early Human Development)
Source: Early Human Development - July 31, 2016 Category: Perinatology & Neonatology Authors: Fleur Lejeune, Morgane R éveillon, Maryline Monnier, Petra S. Hüppi, Cristina Borradori Tolsa, Koviljka Barisnikov Source Type: research

Congenital heart defects in newborns with apparently isolated single gastrointestinal malformation: A retrospective study
Congenital gastrointestinal system malformations/abdominal wall defects (GISM) may appear as isolated defects (single or complex), or in association with multiple malformations. The high incidence of association of GISM and congenital heart defects (CHD) in patients with syndromes and malformative sequences is known, but less expected is the association of apparently isolated single GISM and CHD. The aim of this study was to investigate the frequency of CHD in newborns with isolated GISM, and the possibility to modify the diagnostic-therapeutic approach just before the onset of cardiac symptoms or complications. (Source: E...
Source: Early Human Development - July 29, 2016 Category: Perinatology & Neonatology Authors: Ingrid Anne Mandy Schierz, Giuseppa Pinello, Mario Giuffr è, Simona La Placa, Ettore Piro, Giovanni Corsello Source Type: research

Group B streptococcus infections in neonates admitted to a German NICU: Emphasis on screening and adherence to pre-analytical recommendations
Infections by group B streptococci (GBS), e.g. Streptococcus agalactiae, presenting as early-onset disease (EOD) or late-onset disease (LOD), are leading causes of severe infections in newborn and premature patients. Although screening and intra partum antibiotic prophylaxis are frequently performed, vertically transmitted GBS remain a challenge for pediatrics. (Source: Early Human Development)
Source: Early Human Development - July 28, 2016 Category: Perinatology & Neonatology Authors: Claudia Reinheimer, Volkhard A.J. Kempf, Boris E. Wittekindt, Antje Allendorf, Thomas A. Wichelhaus, Michael Hogardt, Rolf L. Schl ößer, Doris Fischer Source Type: research

Exposure to PBB-153 and Digit Ratio
The ratio between the second and fourth digits is a sexually dimorphic measure, established in utero and linked to prenatal sex steroid levels. An association was found between prenatal levels of Polybrominated Biphenyls, a synthetic chemical suspected to disrupt the endocrine system function, and the digit ratio in adult women. (Source: Early Human Development)
Source: Early Human Development - July 26, 2016 Category: Perinatology & Neonatology Authors: Tamar Wainstock, Brad Pearce, Dana B. Barr, Mary E. Marder, Metrecia Terrell, Michele Marcus Source Type: research

Pain coping strategies: Neonatal intensive care unit survivors in adolescence
Data on long-term consequences of preterm birth on pain coping later in life are limited. (Source: Early Human Development)
Source: Early Human Development - July 25, 2016 Category: Perinatology & Neonatology Authors: Christ-jan van Ganzewinkel, Jasper V. Been, Jeanne P. Dieleman, Titia Katgert, Tera Boelen-van der Loo, Sylvia M. Van der Pal, Monique van Dijk, Boris W. Kramer, Peter Andriessen Source Type: research

Effects of an intervention program on maternal and paternal parenting stress after preterm birth: A randomized trial
Preterm birth causes parenting stress and increases the risk of developmental disorders in children. Our objective was to assess the impact of an early psychological intervention, Triadic parent-infant Relationship Therapy (TRT), on parenting stress, parental mental health and preterm infant development in the motor, language, social, behavioral and emotional domains at a corrected age of 18months. (Source: Early Human Development)
Source: Early Human Development - July 20, 2016 Category: Perinatology & Neonatology Authors: Sophie Castel, Anne Beunard, Christian Creveuil, Xavier Blaizot, Nadine Proia, Bernard Guillois Source Type: research