Relationship between transcutaneous bilirubin and circulating unbound bilirubin in jaundiced neonates
Transcutaneous bilirubin (TcB) consists of the skin-deposited bilirubin. Free bilirubin represents the protein-unbound bilirubin (UB) that is able to pass into the tissues. We aimed to describe the relationship UB-TcB and study the passage of UB into the skin. (Source: Early Human Development)
Source: Early Human Development - November 9, 2016 Category: Perinatology & Neonatology Authors: Emmanuelle Letamendia-Richard, Rafik Ben Ammar, Ascanio Tridente, Daniele De Luca Source Type: research

The sex ratio at birth in South Africa may be a sentinel health indicator
This study was carried out in order to ascertain whether improving conditions in South Africa as measured by available health indicators, were associated with a rise in M/T in this country. (Source: Early Human Development)
Source: Early Human Development - November 4, 2016 Category: Perinatology & Neonatology Authors: Victor Grech, Gwinyai Masukume Source Type: research

The ontogeny of fidgety movements from 4 to 20weeks post-term age in healthy full-term infants
Fidgety movements (FMs) are an early accurate marker for normal development. (Source: Early Human Development)
Source: Early Human Development - October 26, 2016 Category: Perinatology & Neonatology Authors: Fabrizio Ferrari, Rossella Frassoldati, Alberto Berardi, Francesca Di Palma, Luca Ori, Laura Lucaccioni, Natascia Bertoncelli, Christa Einspieler Source Type: research

Digit ratio (2D:4D) in primary brain tumor patients: A case-control study
The second-to-fourth digit ratio (2D:4D) reflects prenatal estrogen and testosterone exposure, and is established in utero. Sex steroids are implicated in development and progression of primary brain tumors. (Source: Early Human Development)
Source: Early Human Development - October 13, 2016 Category: Perinatology & Neonatology Authors: Adomas Bunevicius, Sarunas Tamasauskas, Vytenis Pranas Deltuva, Arimantas Tamasauskas, Albertas Sliauzys, Robertas Bunevicius Source Type: research

Best practice critical cardiac care in the neonatal unit
Major congenital or acquired heart disease in neonates presents with cyanosis, hypoxia, acute circulatory failure or cardiogenic shock. Antenatal diagnosis is made in up to 50% but heart disease is unanticipated in the remainder. The presence of significant heart disease in premature infants is also frequently not suspected at first; in general, whatever the underling cardiac anomaly, the clinical condition is worse, deteriorates more quickly and carries a poorer prognosis in premature and low birth weight infants. (Source: Early Human Development)
Source: Early Human Development - October 12, 2016 Category: Perinatology & Neonatology Authors: Michael L. Rigby Source Type: research

Cerebral oxygen saturation during the first 72h after birth in infants diagnosed prenatally with congenital heart disease
Evidence suggests that hypoxic-ischemic brain injury in infants with congenital heart disease already occurs during early life. The aim of our study was, therefore, to assess the course of regional cerebral oxygen saturation (rcSO2) and fractional tissue oxygen extraction (FTOE) during the first 72h after birth in infants with prenatally diagnosed duct-dependent congenital heart disease. In addition, we identified clinical parameters that were associated with rcSO2. (Source: Early Human Development)
Source: Early Human Development - October 11, 2016 Category: Perinatology & Neonatology Authors: Mirthe J Mebius, Michelle E van der Laan, Elise A Verhagen, Marcus TR Roofthooft, Arend F Bos, Elisabeth MW Kooi Source Type: research

Influence of nutritional variables on the onset of necrotizing enterocolitis in preterm infants: A case-control study
Necrotizing enterocolitis (NEC) is a severe pathologic process linked to high neonatal mortality (30%) and other serious complications. Despite constant improvement in neonatal care, NEC still has a very high incidence amongst preterm infants, especially in those under 1500g of birth weight (7 –10%, with slight variations over the last years [1]). (Source: Early Human Development)
Source: Early Human Development - October 6, 2016 Category: Perinatology & Neonatology Authors: Laura Mart ínez-Rodríguez, Javier Estañ, Jose D. Bermudez, Agustin Molina, Veronica Hortelano, Cecilia Martinez-Costa Source Type: research

Pregnant women's cognitive appraisal of a natural disaster affects their children's BMI and central adiposity via DNA methylation: Project Ice Storm
We determined the extent to which DNA methylation mediates the effects of maternal cognitive appraisal of a natural disaster during pregnancy on offspring growth at age 13. Negative maternal cognitive appraisal predicted both lower BMI and central adiposity via DNA methylation of diabetes-related genes, suggesting a protective role of epigenetics. (Source: Early Human Development)
Source: Early Human Development - October 5, 2016 Category: Perinatology & Neonatology Authors: Lei Cao-Lei, Kelsey N. Dancause, Guillaume Elgbeili, David P. Laplante, Moshe Szyf, Suzanne King Source Type: research

Growth in very preterm children: Head growth after discharge is the best independent predictor for cognitive outcome
The contribution of growth parameters to the cognitive outcome of very low birth weight (VLBW)/very preterm (VP) infants is difficult to disentangle from other preterm-birth related factors. (Source: Early Human Development)
Source: Early Human Development - October 3, 2016 Category: Perinatology & Neonatology Authors: Karen Lidzba, Susanne Rodemann, Rangmar Goelz, Ingeborg Kr ägeloh-Mann, Andrea Bevot Source Type: research

Impact of neonatal risk and temperament on behavioral problems in toddlers born preterm
Children born preterm are at risk for later developmental disorders. The present study examined the predictive effects of neonatal, sociodemographic, and temperament characteristics on behavioral outcomes at toddlerhood, in children born preterm. The sample included 100 toddlers born preterm and with very-low-birth-weight, and their mothers. Neonatal characteristics were evaluated using medical records. The mothers were interviewed using the Early Childhood Behavior Questionnaire for temperament assessment, and the Child Behavior Checklist for behavioral assessment. (Source: Early Human Development)
Source: Early Human Development - September 30, 2016 Category: Perinatology & Neonatology Authors: Rafaela Guilherme Monte Cassiano, Claudia Maria Gaspardo, Guilherme Cordaro Bucker Furini, Francisco Eulogio Martinez, Maria Beatriz Martins Linhares Source Type: research

Abnormal findings in brainstem auditory evoked response at 36 –37weeks of postconceptional age in babies with neonatal chronic lung disease
To examine brainstem auditory function at 36 –37weeks of postconceptional age in preterm infants who are diagnosed to have neonatal chronic lung disease (CLD). (Source: Early Human Development)
Source: Early Human Development - September 27, 2016 Category: Perinatology & Neonatology Authors: Ze D. Jiang, Cui Wang Source Type: research

Early determinants of vagal activity at preschool age – With potential dependence on sex
In children, autonomic nervous function is related to various highly prevalent health problems and might therefore represent an early indicator of ill health. (Source: Early Human Development)
Source: Early Human Development - September 27, 2016 Category: Perinatology & Neonatology Authors: Britta K ühne, Bernd Genser, Freia De Bock Source Type: research

Does the development of executive functioning in infants born preterm benefit from maternal directiveness?
This study assessed how maternal parenting behaviors predict individual differences in early development of executive functioning in infants born preterm, and whether this varies with infant temperament, i.e., self-regulation. (Source: Early Human Development)
Source: Early Human Development - September 26, 2016 Category: Perinatology & Neonatology Authors: Eva van de Weijer-Bergsma, Lex Wijnroks, Ingrid C. van Haastert, Jan Boom, Marian J. Jongmans Source Type: research

Predictors for everyday functioning in preschool children born preterm and at term
Everyday life situations like mealtimes, attending preschool and participating in leisure activities are important in a child's life. They consist of sequences of actions that take place within everyday contexts during activities such as dressing, eating, moving indoors and outdoors, and playing [1]. Functioning in the everyday life situations requires both motor skills (for moving around and handling objects) and process skills (the ability to initiate and organize sequences of actions). Everyday functioning also requires skills in communication, interaction with peers and others in the child's context, and being able to ...
Source: Early Human Development - September 25, 2016 Category: Perinatology & Neonatology Authors: Anna Karin Andersson, Lene Martin, Katarina Strand Brodd, Lena Almqvist Source Type: research

Digit ratio (2D:4D) and handgrip strength in a Chinese population of Han ethnicity
In humans, the relative lengths of the index finger to the ring finger (2D:4D) is a sexually dimorphic trait which correlated with prenatal sex steroids and has been increasingly used as a promising tool to evaluate the impact of prenatal hormone exposure in some traits, such as physical performance. Handgrip strength (HGS) is one potent index of physical ability and its relationship with 2D:4D ratio has been discussed in several ethnic groups. (Source: Early Human Development)
Source: Early Human Development - September 25, 2016 Category: Perinatology & Neonatology Authors: Dan Shen, Zhanbing Ma, Lu Wang, Zhenghao Huo, Hong Lu, Junli Zhao, Wenli Qian Source Type: research