Specific characteristics of abnormal general movements are associated with functional outcome at school age
Assessing the quality of general movements (GMs) is a non-invasive tool to identify at early age infants at risk for developmental disorders. (Source: Early Human Development)
Source: Early Human Development - February 18, 2016 Category: Perinatology & Neonatology Authors: Elisa G. Hamer, Arend F. Bos, Mijna Hadders-Algra Source Type: research

Stool bacterial load in preterm infants with necrotising enterocolitis
Resected gut tissue in necrotising enterocolitis (NEC) has a higher bacterial load than controls. Quantitative PCR was performed on longitudinal NEC and control stool samples (n=72). No significant difference in the total bacterial load was found between samples at diagnosis compared to controls or temporally within NEC. (Source: Early Human Development)
Source: Early Human Development - February 16, 2016 Category: Perinatology & Neonatology Authors: Bashir Abdulkadir, Andrew Nelson, Tom Skeath, Emma C.L. Marrs, John D. Perry, Stephen P. Cummings, Nicholas D. Embleton, Janet E. Berrington, Christopher J. Stewart Source Type: research

The conundrum of nucleated red blood cells in premature infants
Dear Sir, (Source: Early Human Development)
Source: Early Human Development - February 16, 2016 Category: Perinatology & Neonatology Authors: Sascha Meyer, Perrine Duppré, Antonia Wissing, Aylin Aygün, Ludwig Gortner, Martin Poryo Source Type: research

In extremely preterm infants, do the Movement Assessment of Infants and the Alberta Infant Motor Scale predict 18-month outcomes using the Bayley-III?
Extremely preterm infants are at high-risk for neurodevelopmental disabilities. The Movement Assessment of Infants (MAI) and the Alberta Infant Motor Scale (AIMS) have been designed to predict outcome with modest accuracy with the Bayley-I or Bayley-II. (Source: Early Human Development)
Source: Early Human Development - February 10, 2016 Category: Perinatology & Neonatology Authors: Francine Lefebvre, Marie-Michèle Gagnon, Thuy Mai Luu, Geneviève Lupien, Véronique Dorval Source Type: research

Cardiovascular biomarkers in paired maternal and umbilical cord blood samples at term and near term delivery
Cardiovascular biomarkers might help to identify fetuses or pregnancies at risk. (Source: Early Human Development)
Source: Early Human Development - February 3, 2016 Category: Perinatology & Neonatology Authors: Martin E. Blohm, Florian Arndt, Jan Sandig, Werner Diehl, Tanja Zeller, Goetz C. Mueller, Claudia Schlesner, Thomas S. Mir, Stefan Blankenberg, Kurt Hecher, Dominique Singer, Jochen Weil Source Type: research

Benefits of aerobic or resistance training during pregnancy on maternal health and perinatal outcomes: A systematic review
To understand what evidence exists with regard to maternal and offspring benefits of aerobic and/or resistance training during pregnancy. (Source: Early Human Development)
Source: Early Human Development - February 3, 2016 Category: Perinatology & Neonatology Authors: Maria Perales, Alejandro Santos-Lozano, Jonatan R. Ruiz, Alejandro Lucia, Ruben Barakat Source Type: research

Summary and synthesis of current knowledge
The current literature suggests that several possible physiological parameters may be altered in the fetus due to maternal gestational physical activity. These parameters include gestational age at birth, birth weight, heart rate (HR), heart rate variability (HRV), breathing movements, and body movements. Variation in these parameters during and after exercise can provide information about both the viability of the fetus as well as its developmental state. A very young gestational age and a high weight at birth are each associated with multiple morbidities, decreased quality of life and even increased mortality. (Source: E...
Source: Early Human Development - February 3, 2016 Category: Perinatology & Neonatology Authors: Dafna Sussman, Stephen J. Lye, Greg D. Wells Source Type: research

Introductory editorial: Effects of maternal physical activity on the fetus
Regular physical activity during an uncomplicated pregnancy has been shown to improve health-related pregnancy outcomes while being harmless for the fetus. The benefits of regular exercise led the American Association of Obstetricians and Gynaecologists (ACOG) to recommend that a minimum of 30min of moderate exercise a day occurs on most days of the week. Many studies have been published on the health benefits of exercise during pregnancy. These benefits include managing weight gain to lower the risk of hypertension, preeclampsia, and gestational diabetes. (Source: Early Human Development)
Source: Early Human Development - February 1, 2016 Category: Perinatology & Neonatology Authors: Dafna Sussman, Stephen J. Lye, Greg D. Wells Tags: Introduction Source Type: research

Potential benefits of physical activity during pregnancy for the reduction of gestational diabetes prevalence and oxidative stress
Changes in quality of nutrition, habits, and physical activity in modern societies increase susceptibility to obesity, which can deleteriously affect pregnancy outcome. In particular, a sedentary lifestyle causes dysfunction in blood flow, which impacts the cardiovascular function of pregnant women. The main molecular mechanism responsible for this effect is the synthesis and bioavailability of nitric oxide, a phenomenon regulated by the antioxidant capacity of endothelial cells. These alterations affect the vascular health of the mother and vascular performance of the placenta, the key organ responsible for the healthy de...
Source: Early Human Development - January 29, 2016 Category: Perinatology & Neonatology Authors: Marcela Cid, Marcelo González Tags: Best practice guidelines Source Type: research

Correcting for prematurity affects developmental test scores in infants born late and moderately preterm
Corrected age is typically applied when assessing the development of children born (Source: Early Human Development)
Source: Early Human Development - January 27, 2016 Category: Perinatology & Neonatology Authors: Shalin A. Parekh, Elaine M. Boyle, Alexa Guy, Samarita Blaggan, Bradley N. Manktelow, Dieter Wolke, Samantha Johnson Source Type: research

Editorial Board
(Source: Early Human Development)
Source: Early Human Development - January 26, 2016 Category: Perinatology & Neonatology Source Type: research

Impact of maternal physical activity on fetal breathing and body movement—A review
Fetal movements, which include body and breathing movement, are important indicators of fetal well-being and nervous system development. These have been shown to be affected by intrauterine conditions. While maternal physical activity does induce a change in intrauterine conditions and physiology, its impact on fetal movements is still unclear. This paper will provide a brief review of the literature and outline the current knowledge with regards to the effects of maternal exercise on fetal body and breathing movements. (Source: Early Human Development)
Source: Early Human Development - January 22, 2016 Category: Perinatology & Neonatology Authors: Dafna Sussman, Stephen J. Lye, Greg D. Wells Source Type: research

Fetal and maternal cardiac responses to physical activity and exercise during pregnancy
Since the 1970s, researchers have studied the influence of exercise during pregnancy on offspring heart development. With the knowledge and current evidence of fetal programming effects, research has demonstrated that exercise is safe and beneficial for mother, fetus, and neonate. Predominantly, research has focused on maternal and fetal cardiac adaptations related to aerobic exercise during pregnancy; less is known regarding the effects of resistance or combination (aerobic and resistance) training during pregnancy. (Source: Early Human Development)
Source: Early Human Development - January 21, 2016 Category: Perinatology & Neonatology Authors: Linda E. May, John J.B. Allen, Kathleen M. Gustafson Source Type: research

Fetal and maternal metabolic responses to exercise during pregnancy
Pregnancy is characterized by physiological, endocrine and metabolic adaptations creating a pseudo-diabetogenic state of progressive insulin resistance. These adaptations occur to sustain continuous fetal requirements for nutrients and oxygen. Insulin resistance develops at the level of the skeletal muscle, and maternal exercise, especially activity involving large muscle groups improve glucose tolerance and insulin sensitivity. We discuss the maternal hormonal and metabolic changes associated with a normal pregnancy, the metabolic dysregulation that may occur leading to gestational diabetes mellitus (GDM), and the consequ...
Source: Early Human Development - January 21, 2016 Category: Perinatology & Neonatology Authors: Michelle F. Mottola, Raul Artal Tags: Best practice guidelines Source Type: research

Pre-pregnancy maternal obesity in Greece: A case–control analysis
Pre-pregnancy obesity may cause significant health implications for both mother and neonate. Our study aims to investigate the association between pre-pregnancy Body Mass Index and the risk for cesarean section, admission to Neonatal Intensive Care Unit, macrosomia and preterm delivery, in a Mediterranean country. (Source: Early Human Development)
Source: Early Human Development - January 20, 2016 Category: Perinatology & Neonatology Authors: E. Papachatzi, S. Paparrodopoulos, V. Papadopoulos, G. Dimitriou, A. Vantarakis Source Type: research