Randomized trial of early erythropoietin supplementation after preterm birth: Iron metabolism and outcome
Excess of iron and oxidant injury shortly after birth may be associated with neonatal morbidities in preterm infants. (Source: Early Human Development)
Source: Early Human Development - April 20, 2017 Category: Perinatology & Neonatology Authors: O.M. Peltoniemi, E. Anttila, T. Kaukola, G. Buonocore, M. Hallman Source Type: research
Development of comorbid crying, sleeping, feeding problems across infancy: Neurodevelopmental vulnerability and parenting
Regulatory problems (excessive crying, feeding, and sleeping difficulties), specifically their comorbidity, are early warning signs of future problems. Insensitive parenting and neurodevelopmental vulnerabilities have been suggested as factors explaining development or maintenance of regulatory problems. Nevertheless, none of the previous studies investigated these factors within the same sample across infancy, taking into account the reciprocal influences between maternal sensitivity and regulatory problems. (Source: Early Human Development)
Source: Early Human Development - April 20, 2017 Category: Perinatology & Neonatology Authors: Ayten Bilgin, Dieter Wolke Source Type: research
The ability of early serial developmental assessment to predict outcome at 5years following neonatal hypoxic-ischaemic encephalopathy
Neurodevelopmental difficulties in children following hypoxic-ischaemic encephalopathy (HIE) may not emerge until school age. (Source: Early Human Development)
Source: Early Human Development - April 20, 2017 Category: Perinatology & Neonatology Authors: Catherine M. O'Connor, C. Anthony Ryan, Geraldine B. Boylan, Deirdre M. Murray Source Type: research
Response-based sleep intervention: Helping infants sleep without making them cry
It is common for parents to raise questions about infant sleep patterns when attending infant well-visits during the first year of life [1,2]. In seeking answers to their questions from health practitioners, parents have access to a myriad of resources, including family, friends, web-based sites, social media, as well as parenting books. However, these sources of information often present contradictory best practice recommendations [3]. These contradictions are particularly notable in the areas of Infant Total Sleep time (TST) and parental response and presence when infants transition to sleep [4,5]. (Source: Early Human Development)
Source: Early Human Development - April 18, 2017 Category: Perinatology & Neonatology Authors: Wendy Middlemiss, Helen Stevens, Lael Ridgway, Susan McDonald, Michelle Koussa Source Type: research
Do orally-directed behaviors mediate the relationship between behavioral state and nutritive sucking in preterm infants?
Despite the advancement of assessment and interventions to facilitate oral feeding, many infants born preterm are challenged to achieve full oral feeding [1]. Although infant behavioral state is predictive of nutritive sucking patterns [2 –4], less is known regarding the role of orally-directed behaviors (e.g. mouthing, tonguing, rooting, hand-to-mouth, sucking-on-hand) in facilitating nutritive sucking patterns. Orally-directed behaviors are a sensitive indicator of the infant's behavioral organization [5,6] and infants exhibit th ese behaviors to communicate their readiness to feed. (Source: Early Human Development)
Source: Early Human Development - April 18, 2017 Category: Perinatology & Neonatology Authors: Rosemary White-Traut, Li Liu, Kathleen Norr, Krisitin Rankin, Suzann K. Campbell, Thao Griffith, Rohitkumar Vasa, Victoria Geraldo, Barbara Medoff-Cooper Source Type: research
Neurodevelopmental outcomes of neonates undergoing surgery under general anesthesia for malrotation of intestines
It is difficult to differentiate between the potential adverse effects of general anesthesia (GA) on the developing brain and the role of associated co-morbidities and syndromes that can adversely affect neurodevelopmental outcomes in neonates undergoing GA. Neonates with malrotation of the intestines without volvulus usually do not have co-morbidities or syndromes. In addition, majority of them recover very well after surgery and are discharged home within a few days. Neonates with malrotation are a clean cohort of babies to study the role of a single episode of GA on the developing brain. (Source: Early Human Development)
Source: Early Human Development - April 18, 2017 Category: Perinatology & Neonatology Authors: Suresh Birajdar, Shripada Rao, Judy McMichael Source Type: research
Digit ratio (2D:4D) and handgrip strength are correlated in women (but not in men) in Hui ethnicity
Digit ratio, especially second-to-fourth digit ratio (2D:4D) is used as a biomarker of prenatal testosterone exposure and was found associated with physical ability, such as handgrip strength (HGS). Recently, this association has been discussed in several ethnic groups. (Source: Early Human Development)
Source: Early Human Development - April 17, 2017 Category: Perinatology & Neonatology Authors: Hong Lu, Dan Shen, Lu Wang, Shibo Niu, Chunyue Bai, Zhanbing Ma, Zhenghao Huo Source Type: research
Prenatal concentrations of Perfluoroalkyl substances and early communication development in British girls
Perfluoroalkyl substances (PFAS), found in many household products and classed as endocrine disrupting chemicals, can be transferred through the placenta and are associated with multiple developmental deficits in offspring. Using data from the Avon Longitudinal Study of Parents and Children (ALSPAC), we investigated the association between intrauterine exposure to PFAS and early communication development in 432 mother-daughter dyads at 15 and 38months of age. Concentrations of perfluorooctane sulfonate (PFOS), perfluorooctanoate (PFOA), perfluorohexane sulfonate (PFHxS), and perfluorononanoate (PFNA) were measured in mater...
Source: Early Human Development - April 13, 2017 Category: Perinatology & Neonatology Authors: Zuha Jeddy, Terryl J. Hartman, Ethel V. Taylor, Cayla Poteete, Katarzyna Kordas Source Type: research
Cumulative pain-related stress and developmental outcomes among low-risk preterm infants at one year corrected age
Extensive exposure of preterm infants to pain-related stress (PRS) at a time of physiological immaturity and rapid brain development may contribute to altered neurodevelopment. (Source: Early Human Development)
Source: Early Human Development - April 8, 2017 Category: Perinatology & Neonatology Authors: Iris Morag, Ifat Rotem, Mor Frisch, Israel Hendler, Michal J. Simchen, Leah Leibovitz, Ayala Maayan-Metzger, Tzipora Strauss Source Type: research
The role of maternal anxiety and depressive disorders prior to and during pregnancy and perinatal psychopathological symptoms for early infant diseases and drug administration
Maternal mental health prior to and during pregnancy has been shown to be associated with inflammatory diseases and gastrointestinal complaints in the offspring. Unfortunately, many studies merely focused on perinatal distress without consideration of lifetime anxiety and depressive disorders. (Source: Early Human Development)
Source: Early Human Development - April 8, 2017 Category: Perinatology & Neonatology Authors: Linda Krause, Franziska Einsle, Johanna Petzoldt, Hans-Ulrich Wittchen, Julia Martini Source Type: research
Delivery and feeding mode affects fecal calprotectin levels in infants < 7months old
Elevated fecal calprotectin (FC) is a non-invasive marker of inflammation indicating bowel disease. However, healthy infants have displayed high FC levels, with large variation. We sought to determine what factors might affect FC levels in children (Source: Early Human Development)
Source: Early Human Development - April 6, 2017 Category: Perinatology & Neonatology Authors: Yoo Mi Lee, Chae-Yeon Min, You Jin Choi, Su Jin Jeong Source Type: research
Neonatal neurological examination during the first 6h after birth
Few neurological assessments are easily performed during the first 6h after birth. (Source: Early Human Development)
Source: Early Human Development - April 5, 2017 Category: Perinatology & Neonatology Authors: Domenico M. Romeo, Sarah Bompard, Carmen Cocca, Francesca Serrao, Maria Pia De Carolis, Antonio A. Zuppa, Daniela Ricci, Francesca Gallini, Chiara Maddaloni, Costantino Romagnoli, Eugenio Mercuri Source Type: research
Serial measures of cardiac performance using tissue Doppler imaging velocity in preterm infants < 29weeks gestations
Tissue Doppler imaging (TDI) is a useful marker of myocardial performance in preterm infants. We aimed to demonstrate serial changes in TDI velocity in preterm infants (Source: Early Human Development)
Source: Early Human Development - April 4, 2017 Category: Perinatology & Neonatology Authors: Colm R. Breatnach, Afif EL-Khuffash, Adam James, Naomi McCallion, Orla Franklin Source Type: research
Determinants of pulmonary dead space in ventilated newborn infants
Pulmonary dead space (VD) is an index of ventilation inhomogeneity and one of the determinants of the magnitude of tidal volume to maintain optimal blood gases. (Source: Early Human Development)
Source: Early Human Development - March 31, 2017 Category: Perinatology & Neonatology Authors: Theodore Dassios, Ourania Kaltsogianni, Anne Greenough Source Type: research
Associations of maternal obesity and excessive weight gain during pregnancy with subcutaneous fat mass in infancy
Not much is known about the associations of maternal obesity and excessive gestational weight gain with body fat in infancy. (Source: Early Human Development)
Source: Early Human Development - March 30, 2017 Category: Perinatology & Neonatology Authors: Varsha V. Jharap, Susana Santos, Eric A.P. Steegers, Vincent W.V. Jaddoe, Romy Gaillard Source Type: research
