Sex-related differences in the development of fetal heart rate dynamics
Despite previous efforts to explain the general advantages of female fetuses over males regarding health, sex-related differences in the dynamics or complexity of fetal heart rate (FHR) variability and FHR maturation patterns have not yet been identified. (Source: Early Human Development)
Source: Early Human Development - January 11, 2016 Category: Perinatology & Neonatology Authors: Kyu Nam Kim, Young-Sun Park, Jeong-Kyu Hoh Source Type: research

Test–retest reliability of the Test of Infant Motor Performance Screening Items in infants at risk for impaired functional motor performance
To examine test–retest reliability of the TIMPSI in infants at risk for impaired functional motor performance. (Source: Early Human Development)
Source: Early Human Development - January 9, 2016 Category: Perinatology & Neonatology Authors: Tordis Ustad, Jorunn L. Helbostad, Suzann K. Campbell, Gay L. Girolami, Lone Jørgensen, Gunn Kristin Øberg, Kari Anne I. Evensen Source Type: research

Reply: Analysis of the sex ratio at birth in South Africa increased 9months after the 2010 FIFA World Cup
We thank Dr. David Hood for his interest and comments on our paper [1]. Our detailed responses follow: (Source: Early Human Development)
Source: Early Human Development - January 5, 2016 Category: Perinatology & Neonatology Authors: Gwinyai Masukume, Victor Grech, Hagen Scherb Source Type: research

Cord blood insulin-like growth factor (IGF)-1, IGF-binding proteins and adiponectin, and birth size in offspring of women with mild gestational diabetes
Objective: To clarify the impact of a mild form of gestational diabetes mellitus (GDM) on neonatal birth size, and on insulin-related hormones and adiponectin (AdipoQ) in cord blood.Methods: Two hundred and sixteen Japanese pregnant women diagnosed as having normal glucose tolerance according to the JSOG criteria were enrolled. Of the 216 women, 38 women were reclassified into a mild GDM (mGDM) group according to the IADPSG criteria. Of the remaining 178 women, 135 women with normal 50-g glucose challenge test were reclassified into a normal glucose tolerance (NGT) group. (Source: Early Human Development)
Source: Early Human Development - January 5, 2016 Category: Perinatology & Neonatology Authors: Yu Kanai, Tomohiro Kamoda, Makoto Saito, Satoshi Fujiyama, Kazunori Nishimura, Atsushi Iwabuchi, Yayoi Miyazono, Hiromi Hamada, Ryo Sumazaki Source Type: research

Early functional and morphological brain disturbances in late-onset intrauterine growth restriction
To determine whether the brain disturbances develop in late-onset intrauterine growth restriction (IUGR) before blood flow redistribution towards the fetal brain (detected by Doppler measurements in the middle cerebral artery and umbilical artery). Further, to evaluate predictive values of Doppler arterial indices and umbilical cord blood gases and pH for early functional and/or morphological brain disturbances in late-onset IUGR. (Source: Early Human Development)
Source: Early Human Development - January 4, 2016 Category: Perinatology & Neonatology Authors: Mirta Starčević, Maja Predojević, Dražan Butorac, Jasna Tumbri, Paško Konjevoda, Aida Salihagić Kadić Source Type: research

Systemic inflammation on postnatal days 21 and 28 and indicators of brain dysfunction 2years later among children born before the 28th week of gestation
Systemic inflammation during the first two postnatal weeks in extremely preterm newborns ( (Source: Early Human Development)
Source: Early Human Development - December 28, 2015 Category: Perinatology & Neonatology Authors: Alan Leviton, Elizabeth N. Allred, Raina N. Fichorova, Karl C.K. Kuban, T. Michael O'Shea, Olaf Dammann, for the ELGAN study investigators Source Type: research

Analysis of the sex ratio at birth in South Africa increased 9months after the 2010 FIFA World Cup
I am writing regarding the analysis in the article Masukume, G., & Grech, V. (2015). The sex ratio at birth in South Africa increased 9months after the 2010 FIFA World Cup. (Source: Early Human Development)
Source: Early Human Development - December 27, 2015 Category: Perinatology & Neonatology Authors: David Hood Source Type: research

Respiratory sinus arrhythmia in growth restricted fetuses with normal Doppler hemodynamic indices
The autonomic behavior of growth-restricted fetuses at different evolving hemodynamic stages has not been fully elicited. (Source: Early Human Development)
Source: Early Human Development - December 17, 2015 Category: Perinatology & Neonatology Authors: R. Arias-Ortega, J.C. Echeverría, M. Guzmán-Huerta, L. Camargo-Marín, M.J. Gaitán-González, H. Borboa-Olivares, E. Portilla-Islas, S. Camal-Ugarte, C. Vargas-García, M.R. Ortiz, R. González-Camarena Source Type: research

Immune cell subsets at birth may help to predict risk of late-onset sepsis and necrotizing enterocolitis in preterm infants
Parameters predicting late-onset sepsis (LOS) and necrotizing enterocolitis (NEC) in preterm infants would be valuable. Ten-color flow-cytometry enables the estimation of cellular immune status requiring only small sample volumes. (Source: Early Human Development)
Source: Early Human Development - December 15, 2015 Category: Perinatology & Neonatology Authors: Konrad Bochennek, Esther Fryns, Boris Wittekindt, Horst Buxmann, Andrea Quaiser, Doris Fischer, Thomas Klingebiel, Ulrike Koehl, Rolf Schloesser, Sabine Huenecke Source Type: research

Perinatal nutrition in maternal mental health and child development: Birth of a pregnancy cohort
Mental disorders are one of the leading contributors to the global burden of disease. The Alberta Pregnancy Outcomes and Nutrition (APrON) study was initiated in 2008 to better understand perinatal environmental impacts on maternal mental health and child development. (Source: Early Human Development)
Source: Early Human Development - December 15, 2015 Category: Perinatology & Neonatology Authors: Brenda M.Y. Leung, Gerald F. Giesbrecht, Nicole Letourneau, Catherine J. Field, Rhonda C. Bell, Deborah Dewey, the APrON Study Team Source Type: research

Morphometric characteristics of the umbilical cord and vessels in fetal growth restriction and pre-eclampsia
Reports on the morphometric analysis of umbilical cord (UC) and its vessels have been inconsistent due to varying inclusion criteria and methodology. The current study tried to overcome the limitations of previous studies by comparing the UC in pregnancies complicated by fetal growth restriction (FGR), preeclampsia (PE) and FGR+PE, to healthy controls. (Source: Early Human Development)
Source: Early Human Development - December 8, 2015 Category: Perinatology & Neonatology Authors: Reuven Sharony, Eran Kelz, Tal Biron-Shental, Debora Kidron Source Type: research

Heart rate variability in neonates of type 1 diabetic pregnancy
Cardiomyopathy is a common finding in offspring of pre-gestational type 1 diabetic pregnancy. Echocardiographic and biochemical evidence of fetal cardiac dysfunction have also been reported. Studies suggest that offspring of diabetic mothers (ODM) undergo a fetal programming effect due to the hyperglycaemic intrauterine milieu which increases their risk of cardiovascular morbidity in adult life. Decreased neonatal heart rate variability (HRV) has been described in association with in-utero growth restriction, prematurity, sudden infant death syndrome and congenital heart disease. (Source: Early Human Development)
Source: Early Human Development - December 1, 2015 Category: Perinatology & Neonatology Authors: Noirin E. Russell, Mary F. Higgins, Brendan F. Kinsley, Michael E. Foley, Fionnuala M. McAuliffe Source Type: research

Very preterm adolescents show impaired performance with increasing demands in executive function tasks
Very preterm birth is often associated with executive function deficits later in life. The transition to adolescence increases personal autonomy, independence and, in parallel, the demands placed on executive functions at home and in school. (Source: Early Human Development)
Source: Early Human Development - November 30, 2015 Category: Perinatology & Neonatology Authors: Flavia M. Wehrle, Liane Kaufmann, Laura D. Benz, Reto Huber, Ruth L. O'Gorman, Beatrice Latal, Cornelia F. Hagmann Source Type: research

Using cluster analysis to provide new insights into development of very low birthweight (VLBW) premature infants
Very low birthweight (VLBW) premature infant follow-up studies report on single developmental outcome variables but do not assess profiles of development. (Source: Early Human Development)
Source: Early Human Development - November 30, 2015 Category: Perinatology & Neonatology Authors: Gail S. Ross, L.M. Foran, Baptiste Barbot, K. Mark Sossin, Jeffrey M. Perlman Source Type: research

Association of maternal pre-pregnancy weight, weight gain during pregnancy, and smoking with small-for-gestational-age infants in Japan
The aim of this study was to evaluate the associations of maternal pre-pregnancy body mass index (BMI), weight gain during pregnancy, and smoking, with small-for-gestational-age (SGA) births among Japanese women. (Source: Early Human Development)
Source: Early Human Development - November 26, 2015 Category: Perinatology & Neonatology Authors: Emi Akahoshi, Kazuhiko Arima, Kiyonori Miura, Takayuki Nishimura, Yasuyo Abe, Naoko Yamamoto, Kazuyo Oishi, Hideaki Masuzaki, Kiyoshi Aoyagi Tags: Best practice guidelines Source Type: research