Cord blood insulin-like growth factor (IGF)-1, IGF-binding proteins and adiponectin, and birth size in offspring of women with mild gestational diabetes

Objective: To clarify the impact of a mild form of gestational diabetes mellitus (GDM) on neonatal birth size, and on insulin-related hormones and adiponectin (AdipoQ) in cord blood.Methods: Two hundred and sixteen Japanese pregnant women diagnosed as having normal glucose tolerance according to the JSOG criteria were enrolled. Of the 216 women, 38 women were reclassified into a mild GDM (mGDM) group according to the IADPSG criteria. Of the remaining 178 women, 135 women with normal 50-g glucose challenge test were reclassified into a normal glucose tolerance (NGT) group.

Source: Early Human Development - January 5, 2016 Category: Perinatology & Neonatology Authors: Yu Kanai, Tomohiro Kamoda, Makoto Saito, Satoshi Fujiyama, Kazunori Nishimura, Atsushi Iwabuchi, Yayoi Miyazono, Hiromi Hamada, Ryo Sumazaki Source Type: research