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The contributors of emotional distress in painful diabetic neuropathy
Conclusions: This study found a high prevalence of emotional distress in patients with painful DN. It highlights that the differing independent contributors to anxiety and depressive symptoms are based on an individual’s circumstances and experience. We conclude by highlighting the importance of adopting a holistic approach to pain management, incorporating interventions to increase psychological flexibility alongside conventional pharmacological treatments to improve emotional distress in painful DN. (Source: Diabetes and Vascular Disease Research)
Source: Diabetes and Vascular Disease Research - June 16, 2014 Category: Endocrinology Authors: Selvarajah, D., Cash, T., Sankar, A., Thomas, L., Davies, J., Cachia, E., Gandhi, R., Wilkinson, I. D., Wilkinson, N., Emery, C. J., Tesfaye, S. Tags: Original Articles Source Type: research

Suboptimal glycaemic control enhances the risk of impaired prothrombotic state in youths with type 1 diabetes mellitus
Conclusion: Impaired prothrombotic state and consequently endothelial dysfunction are present in youths with T1DM, representing a cumulative risk factor for future cardiovascular disease (CVD). Achievement and maintenance of euglycaemia and normolipidaemia are crucial to decelerate progress of this process. (Source: Diabetes and Vascular Disease Research)
Source: Diabetes and Vascular Disease Research - May 6, 2014 Category: Endocrinology Authors: Kyrgios, I., Maggana, I., Giza, S., Stergidou, D., Mouzaki, K., Kotanidou, E. P., Papadakis, E., Galli-Tsinopoulou, A. Tags: Original Articles Source Type: research

Test-retest reliability of peripheral arterial tonometry in the metabolic syndrome
In conclusion, we have demonstrated that PAT can be used to assess endothelial dysfunction in adults with the metabolic syndrome as reliably as in healthy samples. (Source: Diabetes and Vascular Disease Research)
Source: Diabetes and Vascular Disease Research - May 6, 2014 Category: Endocrinology Authors: Sauder, K. A., West, S. G., McCrea, C. E., Campbell, J. M., Jenkins, A. L., Jenkins, D. J., Kendall, C. W. Tags: Original Articles Source Type: research

Prevalence of peripheral vascular disease and its association with carotid intima-media thickness and arterial stiffness in type 2 diabetes: The Chennai Urban Rural Epidemiology Study (CURES 111)
In conclusion, among urban south Indian type 2 diabetic subjects, the prevalence of PVD is 8.3% and IMT is more strongly associated with PVD than AGI. (Source: Diabetes and Vascular Disease Research)
Source: Diabetes and Vascular Disease Research - May 6, 2014 Category: Endocrinology Authors: Pradeepa, R., Chella, S., Surendar, J., Indulekha, K., Anjana, R. M., Mohan, V. Tags: Original Articles Source Type: research

Decade-long trends in the characteristics, management and hospital outcomes of diabetic patients with ST-segment elevation myocardial infarction
Conclusion: Despite reduced hospital mortality in patients hospitalized with STEMI, diabetic patients continue to experience significantly more adverse outcomes than non-diabetics. (Source: Diabetes and Vascular Disease Research)
Source: Diabetes and Vascular Disease Research - May 6, 2014 Category: Endocrinology Authors: Tisminetzky, M., Joffe, S., McManus, D. D., Darling, C., Gore, J. M., Yarzebski, J., Lessard, D., Goldberg, R. J. Tags: Original Articles Source Type: research

The flavonols quercetin and 3',4'-dihydroxyflavonol reduce platelet function and delay thrombus formation in a model of type 1 diabetes
Diabetes is associated with increased cardiovascular risk. We have recently shown that the naturally occurring flavonol quercetin (Que) or the synthetic flavonol 3',4'-dihydroxyflavonol (DiOHF) inhibits platelet function and delays thrombus formation in healthy mice. Therefore, the aim of this study was to investigate the effect of Que or DiOHF treatment on platelet function and ferric chloride–induced carotid artery thrombosis in a mouse model of type 1 diabetes. Diabetic mice treated with Que or DiOHF maintained blood flow at a significantly higher level than untreated diabetic mice at the end of the recording peri...
Source: Diabetes and Vascular Disease Research - May 6, 2014 Category: Endocrinology Authors: Mosawy, S., Jackson, D. E., Woodman, O. L., Linden, M. D. Tags: Original Articles Source Type: research

ESC Guidelines on diabetes, pre-diabetes, and cardiovascular diseases developed in collaboration with the EASD - Summary
(Source: Diabetes and Vascular Disease Research)
Source: Diabetes and Vascular Disease Research - May 6, 2014 Category: Endocrinology Authors: The Task Force on diabetes, pre-diabetes, and cardiovascular diseases of the European Society of Cardiology (ESC) and developed in collaboration with the European Association for the Study of Diabetes (EASD) Tags: ESC Guidelines Summary Source Type: research