High serum superoxide dismutase activity improves radiation-related quality of life in patients with esophageal squamous cell carcinoma
CONCLUSION: In conclusion, high serum SOD activity improved post-radiotherapy quality of life but did not impact the prognosis of patients with ESCC. To the best of our knowledge, this study is the first to report that serum SOD activity is associated with radiation-induced toxicity and moderately increased radiotherapeutic response in patients with ESCC undergoing radiotherapy. (Source: Clinics)
Source: Clinics - April 26, 2021 Category: General Medicine Source Type: research
Long non-coding RNA KCNQ1 overlapping transcript 1 promotes the progression of esophageal squamous cell carcinoma by adsorbing microRNA-133b
CONCLUSION: KCNQ1OT1 facilitates ESCC progression by sponging miR-133b and activating the EGFR/PI3K/AKT pathway. (Source: Clinics)
Source: Clinics - April 26, 2021 Category: General Medicine Source Type: research
Risk factors for bronchiectasis in patients with chronic obstructive pulmonary disease: a systematic review and meta-analysis
The risk factors of bronchiectasis in patients with chronic obstructive pulmonary disease have not yet been established. This systematic review and meta-analysis aimed to investigate and identify potential risk factors for patients with chronic obstructive pulmonary disease accompanied by bronchiectasis. We reviewed eight electronic journal databases from their inception to November 2019 for observational studies with no language restrictions. The Newcastle-Ottawa Scale was applied to evaluate the quality of the literature. Binary variables were pooled using odds ratios and continuous variables using the standardized mean ...
Source: Clinics - April 16, 2021 Category: General Medicine Source Type: research
Corona Mortis: A Systematic Review of Literature
This study aimed to provide data about anastomosis in an attempt to avoid iatrogenic damage during surgery. Articles were searched online using the descriptor “ Corona Mortis ” in PubMed, Biblioteca Virtual em Sa úde (BVS) (Literatura Latino-Americana e do Caribe em Saúde [LILACS], MEDLINE, indice bibliografico espaãol en ciencias de la salud [IBECS]), and SciELO database. The time range was set between 1995 and 2020. The articles were selected according to their titles and later the abstracts' relation t o our research purpose. All the selected articles were read entirely. A manual search based of the references c...
Source: Clinics - April 16, 2021 Category: General Medicine Source Type: research
Core needle biopsy in fibroepithelial tumors: predicting factors for phyllodes tumors
CONCLUSION: Our data indicate that fibroepithelial lesions of the breast larger than 3 cm are more likely to be phyllodes tumors. (Source: Clinics)
Source: Clinics - April 16, 2021 Category: General Medicine Source Type: research
Systemic Inflammation and Oxidative Stress in Adults with Bronchiectasis: Association with Clinical and Functional Features
CONCLUSIONS: Adults with bronchiectasis presented an increased systemic inflammatory response that correlated negatively with physical capacity. (Source: Clinics)
Source: Clinics - April 16, 2021 Category: General Medicine Source Type: research
The role of platelet to mean platelet volume ratio in the identification of adult-onset still’s disease from sepsis
CONCLUSIONS: PMR could be used as a single indicator or a complementary indicator to distinguish AOSD from sepsis. (Source: Clinics)
Source: Clinics - April 16, 2021 Category: General Medicine Source Type: research
Renin-Angiotensin-Aldosterone System Inhibitors in COVID-19: A Review
This report prompted investigations to identify mechanisms by which blocking angiotensin-converting enzyme 2 (ACE2) could lead to serious consequences in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The possible association between RAAS inhibitors use and unfavorable prognosis in this disease may have been biased by the presence of underlying cardiovascular diseases. As the number of COVID-19 cases has increased worldwide, it has now become possible to investigate the association between RAAS inhibitors and unfavorable prognosis in larger cohorts. Observational studies and one randomized clinical trial fai...
Source: Clinics - April 9, 2021 Category: General Medicine Source Type: research
Ocular motility changes after inferomedial wall and balanced medial plus lateral wall orbital decompression in Graves’ orbitopathy: a randomized prospective comparative study
CONCLUSIONS: IM-OD is as safe as ML-OD with regard to new-onset strabismus, and represents a good alternative for patients who do not require significant exophthalmos reduction. ML-OD offers greater exophthalmos reduction and smoother postoperative recovery. Patients with preoperative enlarged medial rectus muscle on CT are at risk for new-onset esotropia, and preoperative esotropia is likely to increase after OD. (Source: Clinics)
Source: Clinics - April 9, 2021 Category: General Medicine Source Type: research
Vitamin D status and prevalence of hypovitaminosis D in different genders throughout life stages: A Brazilian cross-sectional study
CONCLUSIONS: Mean 25(OH) D values were higher in children and lower in adolescents and women. Approximately 90% of non-seniors and presumably healthy residents of the urban metropolitan region of Rio de Janeiro presented satisfactory levels of 25(OH) D during the summer months; however, in over half of the elderly, the serum concentrations of 25(OH) D were inadequate. Therefore, strategies for the prevention of hypovitaminosis D should be considered in the senior population. (Source: Clinics)
Source: Clinics - April 9, 2021 Category: General Medicine Source Type: research
The novel fibrosis index at diagnosis may predict all-cause mortality in patients with antineutrophil cytoplasmic antibody-associated vasculitis without substantial liver diseases
CONCLUSIONS: NFI ≥ 1.24, which may be an independent predictive marker for all-cause mortality in AAV patients without substantial liver disease. (Source: Clinics)
Source: Clinics - April 9, 2021 Category: General Medicine Source Type: research
Effects of the timing of laparoscopic cholecystectomy after endoscopic retrograde cholangiopancreatography on liver, bile, and inflammatory indices and cholecysto-choledocholithiasis patient prognoses
CONCLUSION: For cholecysto-choledocholithiasis patients, LC at 1-3 d after ERCP can shorten surgical times, reduce intraoperative blood loss, improve liver function and bile biochemistry, relieve inflammatory reactions, reduce complications, and improve prognoses. (Source: Clinics)
Source: Clinics - April 9, 2021 Category: General Medicine Source Type: research
Standardization of an experimental model of intradural injection after spinal cord injury in rats
CONCLUSIONS: The present work standardizes the model of intradural injection in experimental SCI in rats. Intrathecal puncture and injection did not independently cause significant functional or histological changes. (Source: Clinics)
Source: Clinics - March 27, 2021 Category: General Medicine Source Type: research
COVID-19 and the teacher's voice: self-perception and contributions of speech therapy to voice and communication during the pandemic
CONCLUSION: Although teachers generally noticed voice improvements during the pandemic, a proportion of them perceived worsening of voices. Many indicated several factors in which speech-language pathologists could guide them with the aim of improving performance and comfort during remote and hybrid classes, an initiative that will positively impact not only their voice and communication but also their quality of life. (Source: Clinics)
Source: Clinics - March 27, 2021 Category: General Medicine Source Type: research
Modelling the impact of contact tracing of symptomatic individuals on the COVID-19 epidemic
CONCLUSION: Contact tracing of symptomatic individuals may potentially be an alternative strategy when the number of diagnostic tests available is not sufficient for massive testing. (Source: Clinics)
Source: Clinics - March 27, 2021 Category: General Medicine Source Type: research
