COVID-19 and pediatric inflammatory bowel disease: How to manage it?
Pediatric gastroenterologists, family members, and caregivers of patients with inflammatory bowel disease (IBD) are on alert; they are all focused on implementing prophylactic measures to prevent infection by severe acute respiratory syndrome coronavirus 2, evaluating the risks in each patient, guiding them in their treatment, and keeping IBD in remission. To face the current issues of the coronavirus disease pandemic, we have developed a synthesis of the main recommendations of the literature directed at pediatric gastroenterologists in control of patients with pediatric IBD and adapted to the national reality. (Source: Clinics)
Source: Clinics - June 3, 2020 Category: General Medicine Source Type: research
Effects and mechanism of stem cells from human exfoliated deciduous teeth combined with hyperbaric oxygen therapy in type 2 diabetic rats
CONCLUSION: SHED combined with HBO therapy was effective for treating type 2 diabetic rats. The underlying mechanism may involve SHED-mediated increase in the proliferation and trans-differentiation of islet β -cells and decrease in pro-inflammatory cytokines and apoptosis of islets. (Source: Clinics)
Source: Clinics - June 3, 2020 Category: General Medicine Source Type: research
Clinical and laboratory parameters as predictors of long-term outcome according to the etiology of underlying chronic liver disease in patients who underwent liver transplantation for hepatocellular carcinoma treatment
CONCLUSION: Clinical and laboratory characteristics according to etiologic groups were not different, which might have led to comparable long-term outcomes among these patient groups and failure to identify predictors that could aid in better selection of subjects for liver transplantation in the management of this cancer. (Source: Clinics)
Source: Clinics - June 3, 2020 Category: General Medicine Source Type: research
How Institutions Can Protect the Mental Health and Psychosocial Well-Being of Their Healthcare Workers in the Current COVID-19 Pandemic
(Source: Clinics)
Source: Clinics - June 3, 2020 Category: General Medicine Source Type: research
Ultrasound-guided minimally invasive autopsies: A protocol for the study of pulmonary and systemic involvement of COVID-19
Considering that female sexual hormones may modulate the inflammatory response and also exhibit direct effects on the cells of the immune system, herein, we intend to discuss the sex differences and the role of estradiol in modulating the lung and systemic inflammatory response, focusing on its possible application as a treatment modality for SARS-CoV-2 patients. COVID-19 patients develop severe hypoxemia early in the course of the disease, which is silent most of the time. Small fibrinous thrombi in pulmonary arterioles and a tumefaction of endothelial were observed in the autopsies of fatal COVID-19 cases. Studies showed...
Source: Clinics - May 30, 2020 Category: General Medicine Source Type: research
COVID-19 Pandemic as a Driver for Spreading Virtual Care Globally: The Future Starts Now
Considering that female sexual hormones may modulate the inflammatory response and also exhibit direct effects on the cells of the immune system, herein, we intend to discuss the sex differences and the role of estradiol in modulating the lung and systemic inflammatory response, focusing on its possible application as a treatment modality for SARS-CoV-2 patients. COVID-19 patients develop severe hypoxemia early in the course of the disease, which is silent most of the time. Small fibrinous thrombi in pulmonary arterioles and a tumefaction of endothelial were observed in the autopsies of fatal COVID-19 cases. Studies showed...
Source: Clinics - May 30, 2020 Category: General Medicine Source Type: research
Technological Innovation in Outpatient Assistance for Chronic Liver Disease and Liver Transplant Patients During the Coronavirus Disease Outbreak: A Method to Minimize Transmission
Considering that female sexual hormones may modulate the inflammatory response and also exhibit direct effects on the cells of the immune system, herein, we intend to discuss the sex differences and the role of estradiol in modulating the lung and systemic inflammatory response, focusing on its possible application as a treatment modality for SARS-CoV-2 patients. COVID-19 patients develop severe hypoxemia early in the course of the disease, which is silent most of the time. Small fibrinous thrombi in pulmonary arterioles and a tumefaction of endothelial were observed in the autopsies of fatal COVID-19 cases. Studies showed...
Source: Clinics - May 30, 2020 Category: General Medicine Source Type: research
17β-Estradiol, a potential ally to alleviate SARS-CoV-2 infection
Considering that female sexual hormones may modulate the inflammatory response and also exhibit direct effects on the cells of the immune system, herein, we intend to discuss the sex differences and the role of estradiol in modulating the lung and systemic inflammatory response, focusing on its possible application as a treatment modality for SARS-CoV-2 patients. COVID-19 patients develop severe hypoxemia early in the course of the disease, which is silent most of the time. Small fibrinous thrombi in pulmonary arterioles and a tumefaction of endothelial were observed in the autopsies of fatal COVID-19 cases. Studies showed...
Source: Clinics - May 30, 2020 Category: General Medicine Source Type: research
Health literacy and depression in women with type 2 diabetes mellitus
CONCLUSIONS: A negative correlation was identified between health literacy and depression. Self-rated health status, economic satisfaction, employment status, and higher education level are factors that also affect depressive tendency among diabetic women. (Source: Clinics)
Source: Clinics - May 30, 2020 Category: General Medicine Source Type: research
COVID-19, Vascular Diseases, and Vascular Services
(Source: Clinics)
Source: Clinics - May 30, 2020 Category: General Medicine Source Type: research
Lung transplantation during the COVID-19 pandemic
(Source: Clinics)
Source: Clinics - May 30, 2020 Category: General Medicine Source Type: research
Social media: friend or foe in the COVID-19 pandemic?
This article presents expert recommendations for assisting newborn children of mothers with suspected or diagnosed coronavirus disease 2019</mac_aq>(COVID-19). The consensus was developed by five experts with an average of 20 years of experience in neonatal intensive care working at a reference university hospital in Brazil for the care of pregnant women and newborns with suspected or confirmed COVID-19. Despite the lack of scientific evidence regarding the potential for viral transmission to their fetus in pregnant mothers diagnosed with or suspected of COVID-19, it is important to elaborate the lines of care by sp...
Source: Clinics - May 15, 2020 Category: General Medicine Source Type: research
Expert recommendations for the care of newborns of mothers with COVID-19
This article presents expert recommendations for assisting newborn children of mothers with suspected or diagnosed coronavirus disease 2019</mac_aq>(COVID-19). The consensus was developed by five experts with an average of 20 years of experience in neonatal intensive care working at a reference university hospital in Brazil for the care of pregnant women and newborns with suspected or confirmed COVID-19. Despite the lack of scientific evidence regarding the potential for viral transmission to their fetus in pregnant mothers diagnosed with or suspected of COVID-19, it is important to elaborate the lines of care by sp...
Source: Clinics - May 15, 2020 Category: General Medicine Source Type: research
Surgical Practice in the Current COVID-19 Pandemic: A Rapid Systematic Review
The coronavirus disease (COVID-19) outbreak</mac_aq>started in Wuhan, China, in December 2019, and evolved into a global problem in a short period. The pandemic has led to many social and health-care challenges. In this context, surgery is an area that is facing the need for many adaptations. In this systematic literature review, we analyzed different perspectives concerning this situation, aiming to provide recommendations that could guide surgeons and</mac_aq>entities toward screening, elective and emergency surgeries, decision making, and operating room management. A computerized search in PubMed, Scopus, an...
Source: Clinics - May 15, 2020 Category: General Medicine Source Type: research
Susceptibility of the Elderly to SARS-CoV-2 Infection: ACE-2 Overexpression, Shedding, and Antibody-dependent Enhancement (ADE)
The world is currently facing a serious SARS-CoV-2 infection pandemic.</mac_aq>This virus is a new isolate of coronavirus, and the current infection crisis has surpassed the SARS and MERS epidemics</mac_aq> that occurred in 2002 and 2013, respectively. SARS-CoV-2 has currently infected more than 142,000 people, causing</mac_aq>5,000 deaths and spreading across more than 130</mac_aq>countries worldwide. The spreading capacity of the virus clearly demonstrates the potential threat</mac_aq>of respiratory viruses to human health, thereby reiterating to the governments around the world that prevent...
Source: Clinics - May 15, 2020 Category: General Medicine Source Type: research
