Microablative fractional radiofrequency as a therapeutic option for vulvar lichen sclerosus: a pilot study
CONCLUSIONS: MFR may be an effective and safe treatment for symptomatic VLS. (Source: Clinics)
Source: Clinics - March 27, 2021 Category: General Medicine Source Type: research
Evaluation of the RSNA and CORADS classifications for COVID-19 on chest computed tomography in the Brazilian population
CONCLUSION: The RSNA and CORADS classifications showed excellent inter-observer agreement for reviewers with the same level of experience, although the agreement between less experience reviewers and the reviewer with the most experience was only reasonable. Combined analysis of both classifications with the first RT-PCR results did not reveal any false-negative results for detecting COVID-19 in patients. (Source: Clinics)
Source: Clinics - March 27, 2021 Category: General Medicine Source Type: research
Hearing loss, tinnitus, and hypertension: analysis of the baseline data from the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil)
CONCLUSION: Hearing thresholds were worse in participants with hypertension. However, after adjusting for age, sex, diagnosis of diabetes, and exposure to noise, no significant differences were observed between participants with and without hypertension. A higher prevalence of tinnitus was observed in participants with hypertension compared to those without hypertension, but without significance after adjusting for age. (Source: Clinics)
Source: Clinics - March 27, 2021 Category: General Medicine Source Type: research
Efficacy of abdominal ultrasound inspection in the diagnosis and prognosis of neonatal necrotizing enterocolitis
CONCLUSIONS: The application of abdominal color Doppler US can provide high accuracy and sensitivity in NEC diagnosis and also contribute to its prognosis, without induction of radiation. Suspected neonates should be examined using this technique as early as possible. (Source: Clinics)
Source: Clinics - March 27, 2021 Category: General Medicine Source Type: research
Considerations about ethical and legal aspects at the end of life during the COVID-19 pandemic
(Source: Clinics)
Source: Clinics - March 27, 2021 Category: General Medicine Source Type: research
Insights into the Classification of Cardiomyopathies: Past, Present, and Future Directions
(Source: Clinics)
Source: Clinics - March 27, 2021 Category: General Medicine Source Type: research
Post-coronavirus disease syndrome and disseminated microthrombosis: the role of the von Willebrand factor and antiphospholipid antibodies
The novel coronavirus disease (COVID-19) showed increased morbidity and mortality rates and worse prognosis in individuals with underlying chronic diseases, especially cardiovascular disease and its risk factors, such as hypertension, diabetes, and obesity. There is also evidence of possible links among COVID-19, myocardial infarction, and stroke. Emerging evidence suggests a pro-inflammatory milieu and hypercoagulable state in patients with this infection. Despite anticoagulation, a large proportion of patients requiring intensive care may develop life-threatening thrombotic complications. Indeed, the levels of some marke...
Source: Clinics - March 24, 2021 Category: General Medicine Source Type: research
Assistance and health care provided to adolescents with chronic and immunosuppressive conditions in a tertiary university hospital during the COVID-19 pandemic
The novel coronavirus disease (COVID-19) showed increased morbidity and mortality rates and worse prognosis in individuals with underlying chronic diseases, especially cardiovascular disease and its risk factors, such as hypertension, diabetes, and obesity. There is also evidence of possible links among COVID-19, myocardial infarction, and stroke. Emerging evidence suggests a pro-inflammatory milieu and hypercoagulable state in patients with this infection. Despite anticoagulation, a large proportion of patients requiring intensive care may develop life-threatening thrombotic complications. Indeed, the levels of some marke...
Source: Clinics - March 24, 2021 Category: General Medicine Source Type: research
COVID-19 and Thromboinflammation: Is There a Role for Statins?
The novel coronavirus disease (COVID-19) showed increased morbidity and mortality rates and worse prognosis in individuals with underlying chronic diseases, especially cardiovascular disease and its risk factors, such as hypertension, diabetes, and obesity. There is also evidence of possible links among COVID-19, myocardial infarction, and stroke. Emerging evidence suggests a pro-inflammatory milieu and hypercoagulable state in patients with this infection. Despite anticoagulation, a large proportion of patients requiring intensive care may develop life-threatening thrombotic complications. Indeed, the levels of some marke...
Source: Clinics - March 24, 2021 Category: General Medicine Source Type: research
Geriatric nutritional risk index predicts all-cause mortality in patients with heart failure: A systematic review and meta-analysis
CONCLUSIONS: GNRI is a simple and well-established nutritional assessment tool to predict all-cause mortality in patients with HF. (Source: Clinics)
Source: Clinics - March 24, 2021 Category: General Medicine Source Type: research
Efficacy of short-term moderate or high-dose statin therapy for the prevention of contrast-induced nephropathy in high-risk patients with chronic kidney disease: systematic review and meta-analysis
Although previous studies have indicated that statin therapy can effectively prevent the development of CIN, this observation remains controversial, especially in high-risk patients. A meta-analysis was performed to evaluate the efficacy of statin pretreatment for preventing the development of CIN in patients with chronic kidney disease (CKD) and to determine its effectiveness in various subgroups. We searched the online databases PubMed, EMBASE, and the Cochrane Library. RCTs that involved the comparison of the short-term moderate or high-dose statin pretreatment with placebo for CIN prevention in CKD patients undergoing ...
Source: Clinics - March 24, 2021 Category: General Medicine Source Type: research
Is it Safe to Perform Elective Colorectal Surgical Procedures during the COVID-19 Pandemic? A Single Institution Experience with 103 Patients
CONCLUSION: Our study demonstrated that elective colorectal surgical procedures may be safely performed during the pandemic; however, preoperative testing should be performed to reduce in-hospital infection rates, since the mortality rate due to SARS-CoV-2 in this setting is particularly high. (Source: Clinics)
Source: Clinics - March 24, 2021 Category: General Medicine Source Type: research
Medical students with performance difficulties need wide support: Initial results of an academic tutoring program
CONCLUSIONS: The Academic Tutoring Program showed positive results for most of the students. Close monitoring and tutor intervention allowed students with poor academic performance to overcome the low performance cycle. These important tasks demand time and energy from tutors, and institutional recognition of these professionals is essential for the successful maintenance of the program. (Source: Clinics)
Source: Clinics - March 24, 2021 Category: General Medicine Source Type: research
Multicomponent physical activity program to prevent body changes and metabolic disturbances associated with antiretroviral therapy and improve quality of life of people living with HIV: a pragmatic trial
CONCLUSIONS: Understanding how effective PA is in preventing body changes and metabolic disturbances, and in improving the quality of PLH starting ART may help establish guidelines to better incorporate PA in HIV care. (Source: Clinics)
Source: Clinics - March 24, 2021 Category: General Medicine Source Type: research
Association of tumor mutation burden and epidermal growth factor receptor inhibitor history with survival in patients with metastatic stage III/IV non-small-cell lung cancer: A retrospective study
CONCLUSIONS: EGFR inhibitor treatment history and tumor mutation load are risk factors for the overall survival of patients with stage III/IV NSCLC who have undergone only hospice care. These results provide a critical clinical basis for further study of nontraditional anti-tumor responses induced by EGFR inhibitors. (Source: Clinics)
Source: Clinics - March 24, 2021 Category: General Medicine Source Type: research
