Ulcer pressure prevention and opportunity for innovation during the COVID-19 crisis
The aim of this study was to evaluate whether there is a relationship between bleeding response and radiotherapy dose to palliate patients with local recurrence or progression of gastric cancer (GC). To this end, we conducted a systematic review and meta-analysis of observational studies that evaluated the bleeding response in patients with GC with local recurrence or progression. A meta-regression analysis between biological effective dose (BED) and bleeding response was performed, as was subgroup analysis to evaluate the outcome by BED level and radiotherapy (RT) technique. A p-value<0.05 was considered significant. T...
Source: Clinics - September 2, 2020 Category: General Medicine Source Type: research
Palliative radiotherapy for gastric cancer: Is there a dose relationship between bleeding response and radiotherapy?
The aim of this study was to evaluate whether there is a relationship between bleeding response and radiotherapy dose to palliate patients with local recurrence or progression of gastric cancer (GC). To this end, we conducted a systematic review and meta-analysis of observational studies that evaluated the bleeding response in patients with GC with local recurrence or progression. A meta-regression analysis between biological effective dose (BED) and bleeding response was performed, as was subgroup analysis to evaluate the outcome by BED level and radiotherapy (RT) technique. A p-value<0.05 was considered significant. T...
Source: Clinics - September 2, 2020 Category: General Medicine Source Type: research
Aprepitant plus palonosetron for the prevention of postoperative nausea and vomiting after breast cancer surgery: a double blind, randomized trial
CONCLUSION: The addition of aprepitant as a third antiemetic resulted in no significant reduction in the incidence of PONV in this population. However, the incidence of PONV was reduced in relation to the general population. (Source: Clinics)
Source: Clinics - September 2, 2020 Category: General Medicine Source Type: research
Characteristics and outcomes of patients with COVID-19 admitted to the ICU in a university hospital in São Paulo, Brazil - study protocol
CONCLUSIONS: This study will provide epidemiological data about critically ill patients with COVID-19 in Brazil, which could inform health policy and resource allocation in low- and middle-income countries. (Source: Clinics)
Source: Clinics - August 26, 2020 Category: General Medicine Source Type: research
Physical activity among women of low socioeconomic status living with HIV in two major cities of Brazil and Mozambique: A cross-sectional comparative study
This study compared the PA assessed by accelerometers in women of low SES living with HIV under common antiretroviral therapy (cART) from two major cities in Brazil (Rio de Janeiro, n=33; 40.1 ±6.1 years) and Mozambique (Maputo, n=50; 38.8±8.7 years). METHODS: Eligible women wore triaxial accelerometers during seven consecutive days, to estimate their habitual PA and daily energy expenditure. RESULTS: The proportion of participants with overweight/obesity was greater in Rio than Maput o (57% vs. 30%; p=0.021), as well as those classified as sedentary based on steps/day (45% vs. 22%; p=0.02). Sedentary time was prevalen...
Source: Clinics - August 26, 2020 Category: General Medicine Source Type: research
Association of bone mineral density with bone texture attributes extracted using routine magnetic resonance imaging
CONCLUSION: Specific TAs could be reliably extracted from routine MRI and correlated with BMD. Our results encourage future evaluation of the potential usefulness of quantitative texture measurements from MRI scans for predicting fragility fractures. (Source: Clinics)
Source: Clinics - August 26, 2020 Category: General Medicine Source Type: research
Cost Modifications during the Early Years of the Use of the National Cardiovascular Data Registry for Quality Improvement
CONCLUSION: The use of the NCDR® as a benchmark to guide QI programs outside the United States was associated with the positive impact of bending the cost curve to below that of national medical inflation and the comparison hospitals ’ costs, with a lower incidence of hospital readmission. (Source: Clinics)
Source: Clinics - August 26, 2020 Category: General Medicine Source Type: research
Cut-off point for high dysphonia risk in children based on the Child Dysphonia Risk Screening Protocol: preliminary findings
CONCLUSION: A cut-off point for high dysphonia risk was calculated. The DRSP-C proved to be a promising tool for children ’ s clinical vocal and health promotion and should be used in conjunction with General Dysphonia Risk Screening. (Source: Clinics)
Source: Clinics - August 26, 2020 Category: General Medicine Source Type: research
Circulating Exosomal microRNAs as Biomarkers of Systemic Lupus Erythematosus
CONCLUSIONS: These findings suggested that exosomal miR-21 and miR-155 expression levels may serve as potential biomarkers for the diagnosis of SLE and LN. (Source: Clinics)
Source: Clinics - August 26, 2020 Category: General Medicine Source Type: research
The interference of COVID-19 in the male reproductive system: Important questions and the future of assisted reproduction techniques
(Source: Clinics)
Source: Clinics - August 26, 2020 Category: General Medicine Source Type: research
The influence of bitter-taste receptor (TAS2R) expression in pharmacological response to Chloroquine in obese patients with COVID-19
(Source: Clinics)
Source: Clinics - August 26, 2020 Category: General Medicine Source Type: research
Contributions of residents from multiple specializations in managing the COVID-19 pandemic in the largest public hospital Brazil
Rotator cuff tears are common among the elderly, and studies on the outcomes after rotator cuff repair in the elderly are limited. We carried out this meta-analysis with systematic literature search, aiming to clarify the outcomes after rotator cuff repair in the elderly as assessed by the American Shoulder and Elbow Surgeons (ASES) shoulder score. We conducted a literature search through October 2019 in PubMed and EMBASE databases and performed meta-analysis to calculate the summary mean difference comparing the post- and pre-operation ASES scores under both fixed-effect and random-effect models. Among 4978 studies identi...
Source: Clinics - August 20, 2020 Category: General Medicine Source Type: research
Parathyroid surgery during the COVID-19 pandemic: Time to think about the “New Normal”
Rotator cuff tears are common among the elderly, and studies on the outcomes after rotator cuff repair in the elderly are limited. We carried out this meta-analysis with systematic literature search, aiming to clarify the outcomes after rotator cuff repair in the elderly as assessed by the American Shoulder and Elbow Surgeons (ASES) shoulder score. We conducted a literature search through October 2019 in PubMed and EMBASE databases and performed meta-analysis to calculate the summary mean difference comparing the post- and pre-operation ASES scores under both fixed-effect and random-effect models. Among 4978 studies identi...
Source: Clinics - August 20, 2020 Category: General Medicine Source Type: research
Cancer pain treatment during the COVID-19 pandemic: institutional recommendations
Rotator cuff tears are common among the elderly, and studies on the outcomes after rotator cuff repair in the elderly are limited. We carried out this meta-analysis with systematic literature search, aiming to clarify the outcomes after rotator cuff repair in the elderly as assessed by the American Shoulder and Elbow Surgeons (ASES) shoulder score. We conducted a literature search through October 2019 in PubMed and EMBASE databases and performed meta-analysis to calculate the summary mean difference comparing the post- and pre-operation ASES scores under both fixed-effect and random-effect models. Among 4978 studies identi...
Source: Clinics - August 20, 2020 Category: General Medicine Source Type: research
Bioethical principles and values during pandemics
Rotator cuff tears are common among the elderly, and studies on the outcomes after rotator cuff repair in the elderly are limited. We carried out this meta-analysis with systematic literature search, aiming to clarify the outcomes after rotator cuff repair in the elderly as assessed by the American Shoulder and Elbow Surgeons (ASES) shoulder score. We conducted a literature search through October 2019 in PubMed and EMBASE databases and performed meta-analysis to calculate the summary mean difference comparing the post- and pre-operation ASES scores under both fixed-effect and random-effect models. Among 4978 studies identi...
Source: Clinics - August 20, 2020 Category: General Medicine Source Type: research
