Update on the diagnosis and management of COVID-19 in pediatric patients
Coronavirus disease (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), became a pandemic in March 2020, affecting millions of people worldwide. However, COVID-19 in pediatric patients represents 1-5% of all cases, and the risk for developing severe disease and critical illness is much lower in children with COVID-19 than in adults. Multisystem inflammatory syndrome in children (MIS-C), a possible complication of COVID-19, has been described as a hyperinflammatory condition with multiorgan involvement similar to that in Kawasaki disease or toxic shock syndrome in children with evidence of SA...
Source: Clinics - December 1, 2020 Category: General Medicine Source Type: research
Differences among Severe Cases of Sars-CoV-2, Influenza, and Other Respiratory Viral Infections in Pediatric Patients: Symptoms, Outcomes and Preexisting Comorbidities
CONCLUSION: Severe COVID-19 had a higher mortality rate than other viral respiratory illnesses, despite the lower frequency of fever, cough, dyspnea, respiratory distress, and desaturation. Death risk was strongly associated with preexisting comorbidities. (Source: Clinics)
Source: Clinics - December 1, 2020 Category: General Medicine Source Type: research
Comparative evaluation of Latanoprostene Bunod, Timolol Maleate, and latanoprost Ophthalmic Solutions to assess their safety and efficacy in lowering intraocular pressure for the management of Open-Angle Glaucoma
CONCLUSION: Latanoprostene bunod was superior to latanoprost and timolol for the treatment of open-angle glaucoma. (Source: Clinics)
Source: Clinics - December 1, 2020 Category: General Medicine Source Type: research
Increased Serum Expression of Inflammatory Cytokines may Serve as Potential Diagnostic Biomarker for Bilirubin Encephalopathy
CONCLUSION: IL-1 β and TGF- β levels were upregulated in BE and might function as potential biomarkers or therapeutic targets for BE patients. (Source: Clinics)
Source: Clinics - December 1, 2020 Category: General Medicine Source Type: research
Prevalence of Sarcopenic Obesity and its Association with Functionality, Lifestyle, Biomarkers and Morbidities in Older Adults: the FIBRA-RJ Study of Frailty in Older Brazilian Adults
CONCLUSION: The study showed a high prevalence of sarcopenic obesity in non-institutionalized older adults in Brazil. The finding that this condition was associated with modifiable risk factors may provide insights into measures directed at prevention and reduction of the risk of sarcopenic obesity in this population subgroup. (Source: Clinics)
Source: Clinics - December 1, 2020 Category: General Medicine Source Type: research
Effects of an Intratympanic Injection of Dexamethasone Combined with Gentamicin on the Expression Level of Serum P0 Protein Antibodies in Patients with Meniere’s Disease
CONCLUSION: For patients with MD, dexamethasone combined with gentamicin can reduce the incidence of vertigo, tinnitus, and gait instability, but it has no effect on the efficacy or number of vertigo attacks 6 months after treatment. Therefore, the levels of myelin P0 protein antibodies after treatment can be used as predictors of vertigo at 6 months after treatment. (Source: Clinics)
Source: Clinics - December 1, 2020 Category: General Medicine Source Type: research
COVID-19 pandemic: Challenges and advances in the Physical Therapy, Speech-Language-Hearing Science, and Occupational Therapy undergraduate programs in Brazil
(Source: Clinics)
Source: Clinics - December 1, 2020 Category: General Medicine Source Type: research
Neonatal manifestations in COVID-19 patients at a Brazilian tertiary center
Here we used a meta-analysis of several clinical trials to determine whether anti-Helicobacter pylori therapy has any positive effect on IBS patients. Here we compared the effective clinical remission rates between IBS patients treated with anti-H. pylori therapy and those who were not. This data would provide more clinical evidence regarding the efficacy of novel treatments and intervention points for IBS patients. Relevant studies were identified using keyword searches on various electronic databases, including PubMed, Embase, the Cochrane Central Register of Controlled Trials, CNKI, and CBM. Keywords included “ helico...
Source: Clinics - November 27, 2020 Category: General Medicine Source Type: research
Comments on “Evaluation of the Accuracy of Mammography, Ultrasound and Magnetic Resonance Imaging in Suspect Breast Lesions”
Here we used a meta-analysis of several clinical trials to determine whether anti-Helicobacter pylori therapy has any positive effect on IBS patients. Here we compared the effective clinical remission rates between IBS patients treated with anti-H. pylori therapy and those who were not. This data would provide more clinical evidence regarding the efficacy of novel treatments and intervention points for IBS patients. Relevant studies were identified using keyword searches on various electronic databases, including PubMed, Embase, the Cochrane Central Register of Controlled Trials, CNKI, and CBM. Keywords included “ helico...
Source: Clinics - November 27, 2020 Category: General Medicine Source Type: research
Potential mouth rinses and nasal sprays that reduce SARS-CoV-2 viral load: What we know so far?
Here we used a meta-analysis of several clinical trials to determine whether anti-Helicobacter pylori therapy has any positive effect on IBS patients. Here we compared the effective clinical remission rates between IBS patients treated with anti-H. pylori therapy and those who were not. This data would provide more clinical evidence regarding the efficacy of novel treatments and intervention points for IBS patients. Relevant studies were identified using keyword searches on various electronic databases, including PubMed, Embase, the Cochrane Central Register of Controlled Trials, CNKI, and CBM. Keywords included “ helico...
Source: Clinics - November 27, 2020 Category: General Medicine Source Type: research
Comments on “Transcutaneous tibial nerve stimulation versus parasacral stimulation in the treatment of overactive bladder in elderly people: A triple-blinded randomized controlled trial”
Here we used a meta-analysis of several clinical trials to determine whether anti-Helicobacter pylori therapy has any positive effect on IBS patients. Here we compared the effective clinical remission rates between IBS patients treated with anti-H. pylori therapy and those who were not. This data would provide more clinical evidence regarding the efficacy of novel treatments and intervention points for IBS patients. Relevant studies were identified using keyword searches on various electronic databases, including PubMed, Embase, the Cochrane Central Register of Controlled Trials, CNKI, and CBM. Keywords included “ helico...
Source: Clinics - November 27, 2020 Category: General Medicine Source Type: research
Cardiac Magnetic Resonance Analysis of Mitral Annular Dynamics after Mitral Valve Repair
CONCLUSION: We observed a significant reduction in the MA size after MVR, with preservation of the MA mobility at the 2-year follow-up. (Source: Clinics)
Source: Clinics - November 27, 2020 Category: General Medicine Source Type: research
Validation of an Overnight Wireless High-Resolution Oximeter plus Cloud-Based Algorithm for the Diagnosis of Obstructive Sleep Apnea
CONCLUSION: Our results showed that ODM is a simple and accurate method for the diagnosis of OSA. (Source: Clinics)
Source: Clinics - November 27, 2020 Category: General Medicine Source Type: research
The need to standardize use of the newly deceased in medical trainings
CONCLUSION: According to the findings, the significance of — and need for — training is undeniable. Hence, it is urgent to normalize the practice and definition of the ethical limitations of medical conduct. (Source: Clinics)
Source: Clinics - November 27, 2020 Category: General Medicine Source Type: research
Levels of matrix metalloproteinase-9 and tissue inhibitor of metalloproteinase-1 are related to cardiopulmonary injury in fetal inflammatory response syndrome
CONCLUSION: MMP-9, TIMP-1, and the MMP-9/TIMP-1 ratio revealed a certain diagnostic value for FIRS; combined with gestational age, these parameters were effective for predicting cardiopulmonary injury. (Source: Clinics)
Source: Clinics - November 27, 2020 Category: General Medicine Source Type: research
