Lessons from the spatiotemporal expression patterns of RNA vs. proteins during the cell cycle
Single-cell analysisCell-to-cell variationsCell cycleOmicsPrecision medicine (Source: Cardiovascular Research)
Source: Cardiovascular Research - June 28, 2021 Category: Cardiology Source Type: research
Beyond diabetes: a relationship between cardiovascular outcomes and glycaemic index
Glycaemic indexObesityCardiovascular riskGlobalDiabetes (Source: Cardiovascular Research)
Source: Cardiovascular Research - June 24, 2021 Category: Cardiology Source Type: research
The post-pandemic legacy: the breakthrough of digital health and telemedicine
TelemedicineRemote monitoringDigital HealthCOVID-19mHealth (Source: Cardiovascular Research)
Source: Cardiovascular Research - June 18, 2021 Category: Cardiology Source Type: research
Corrigendum to: Scientist on the spot: Exploring the cause and cure for pulmonary arterial hypertension
Cardiovascular Research, Volume 117, Issue 6, 1 June 2021, Pages e82 –e83,https://doi.org/10.1093/cvr/cvab091 (Source: Cardiovascular Research)
Source: Cardiovascular Research - June 18, 2021 Category: Cardiology Source Type: research
IL-15 and IL-7: keys to dysregulated inflammation in acute coronary syndromes
This paper was handled by Guest Editor Thomas F. L üscher. (Source: Cardiovascular Research)
Source: Cardiovascular Research - June 18, 2021 Category: Cardiology Source Type: research
From translation to integration: how to approach the complexity of atrial fibrillation mechanisms
Recent observations that early and aggressive rhythm control for atrial fibrillation (AF) reduces adverse cardiovascular outcomes1 and that catheter ablation may outperform anti-arrhythmic drug therapy as first-line treatment2,3 refuel research efforts for new target mechanisms driving AF. The current spotlight issue ofCardiovascular Research contains a number of very elegant studies adding new mechanistic concepts to our current knowledge of mechanisms involved in AF. (Source: Cardiovascular Research)
Source: Cardiovascular Research - June 15, 2021 Category: Cardiology Source Type: research
COVID-19-related cardiac complications from clinical evidences to basic mechanisms: opinion paper of the ESC Working Group on Cellular Biology of the Heart
AbstractThe pandemic of coronavirus disease (COVID)-19 is a global threat, causing high mortality, especially in the elderly. The main symptoms and the primary cause of death are related to interstitial pneumonia. Viral entry also into myocardial cells mainly via the angiotensin converting enzyme type 2 (ACE2) receptor and excessive production of pro-inflammatory cytokines, however, also make the heart susceptible to injury. In addition to the immediate damage caused by the acute inflammatory response, the heart may also suffer from long-term consequences of COVID-19, potentially causing a post-pandemic increase in cardiac...
Source: Cardiovascular Research - June 12, 2021 Category: Cardiology Source Type: research
Progress in cardiac research: from rebooting cardiac regeneration to a complete cell atlas of the heart
AbstractWe review some of the important discoveries and advances made in basic and translational cardiac research in 2020. For example, in the field of myocardial infarction (MI), new aspects of autophagy and the importance of eosinophils were described. Novel approaches, such as a glycocalyx mimetic, were used to improve cardiac recovery following MI. The strategy of 3D bio-printing was shown to allow the fabrication of a chambered cardiac organoid. The benefit of combining tissue engineering with paracrine therapy to heal injured myocardium is discussed. We highlight the importance of cell-to-cell communication, in parti...
Source: Cardiovascular Research - June 11, 2021 Category: Cardiology Source Type: research
Erratum to: The year in basic vascular biology research: from mechanoreceptors and neutrophil extracellular traps to smartphone data and omics
Cardiovascular Research, cvab105,https://doi.org/10.1093/cvr/cvab105 (Source: Cardiovascular Research)
Source: Cardiovascular Research - June 10, 2021 Category: Cardiology Source Type: research
Challenges and opportunities in improving the management of atrial fibrillation: recent research advances and their clinical translation
Atrial fibrillation (AF) is a problem of major clinical importance, accounting for about 9 million cases in the European Union in 2010 with projections for an almost doubling by 2060.1 The worldwide economic burden of AF was estimated at 6 million disability-adjusted life-years of lost productivity in 2017.2 The average 3-year societal cost per patient in Denmark attributable to AF over the period 2001 –2012 was estimated to be of the order of 25 000 Euros ($30 000), providing an overall cost burden in Europe of the order of 10 billion Euros.3 Clearly, AF is a major issue at the level of public health and economic bu...
Source: Cardiovascular Research - June 4, 2021 Category: Cardiology Source Type: research
Calcium and postoperative atrial fibrillation: round up the usual suspects!
This editorial refers to ‘Altered atrial cytosolic calcium handling contributes to the development of postoperative atrial fibrillation’ by FE. Fakuadeet al., pp. 1790 –1801 (Source: Cardiovascular Research)
Source: Cardiovascular Research - May 29, 2021 Category: Cardiology Source Type: research
Corrigendum to: Platelets, coagulation and the vascular wall - The quest to better understand and smarten up our therapeutic targeting of this triad in primary and secondary prevention of cardiovascular events
Cardiovascular Research, cvab121,https://doi.org/10.1093/cvr/cvab121 (Source: Cardiovascular Research)
Source: Cardiovascular Research - May 25, 2021 Category: Cardiology Source Type: research
Coronary artery disease patients without standard modifiable risk factors (SMuRFs)- a forgotten group calling out for new discoveries
Coronary artery diseaseAtherosclerosisRisk factorsBioinformaticsBiomarkers (Source: Cardiovascular Research)
Source: Cardiovascular Research - May 22, 2021 Category: Cardiology Source Type: research
Scientists on the Spot: Re-awakening the heart ’s regenerative capacity
Cardiac repairRegenerationMicroRNAEmbryonicEndogenous (Source: Cardiovascular Research)
Source: Cardiovascular Research - May 22, 2021 Category: Cardiology Source Type: research
Scientist on the Spot: Exploring the cause and cure for pulmonary arterial hypertension
Pulmonary arterial hypertensionMitochondriaRedoxEpigeneticsPrecision medicine (Source: Cardiovascular Research)
Source: Cardiovascular Research - May 21, 2021 Category: Cardiology Source Type: research
