Interactions of histatin-3 and histatin-5 with actin
Histatins are histidine rich polypeptides produced in the parotid and submandibular gland and secreted into the saliva. Histatin-3 and −5 are the most important polycationic histatins. They possess antimicrobi... (Source: BMC Biochemistry)
Source: BMC Biochemistry - March 6, 2017 Category: Biochemistry Authors: Edna Blotnick, Asaf Sol, Gilad Bachrach and Andras Muhlrad Source Type: research
Systematic substitutions at BLIP position 50 result in changes in binding specificity for class A β-lactamases
The production of β-lactamases by bacteria is the most common mechanism of resistance to the widely prescribed β-lactam antibiotics. β-lactamase inhibitory protein (BLIP) competitively inhibits class A β-lacta... (Source: BMC Biochemistry)
Source: BMC Biochemistry - March 6, 2017 Category: Biochemistry Authors: Carolyn J. Adamski and Timothy Palzkill Source Type: research
Interactions of histatin-3 and histatin-5 with actin
Histatins are histidine rich polypeptides produced in the parotid and submandibular gland and secreted into the saliva. Histatin-3 and −5 are the most important polycationic histatins. They possess antimicrobi... (Source: BMC Biochemistry)
Source: BMC Biochemistry - March 6, 2017 Category: Biochemistry Authors: Edna Blotnick, Asaf Sol, Gilad Bachrach and Andras Muhlrad Source Type: research
Systematic substitutions at BLIP position 50 result in changes in binding specificity for class A β-lactamases
The production of β-lactamases by bacteria is the most common mechanism of resistance to the widely prescribed β-lactam antibiotics. β-lactamase inhibitory protein (BLIP) competitively inhibits class A β-lacta... (Source: BMC Biochemistry)
Source: BMC Biochemistry - March 6, 2017 Category: Biochemistry Authors: Carolyn J. Adamski and Timothy Palzkill Source Type: research
Copper chelation and interleukin-6 proinflammatory cytokine effects on expression of different proteins involved in iron metabolism in HepG2 cell line
In vertebrates, there is an intimate relationship between copper and iron homeostasis. Copper deficiency, which leads to a defect in ceruloplasmin enzymatic activity, has a strong effect on iron homeostasis re... (Source: BMC Biochemistry)
Source: BMC Biochemistry - January 24, 2017 Category: Biochemistry Authors: Luca Marco Di Bella, Roberto Alampi, Flavia Biundo, Giovanni Toscano and Maria Rosa Felice Source Type: research
Knockdown of GGCT inhibits cell proliferation and induces late apoptosis in human gastric cancer
Gamma glutamylcyclotransferase (GGCT) has been proved to be involved in various cancers, but the biological function of GGCT in gastric cancer is still largely unknown. (Source: BMC Biochemistry)
Source: BMC Biochemistry - December 1, 2016 Category: Biochemistry Authors: Wenjie Zhang, Lei Chen, Honggang Xiang, Chunhua Hu, Weibin Shi, Ping Dong and Wenjie Lv Source Type: research
Identification of replication-dependent and replication-independent linker histone complexes: Tpr specifically promotes replication-dependent linker histone stability
There are 11 variants of linker histone H1 in mammalian cells. Beyond their shared abilities to stabilize and condense chromatin, the H1 variants have been found to have non-redundant functions, the mechanisms... (Source: BMC Biochemistry)
Source: BMC Biochemistry - October 1, 2016 Category: Biochemistry Authors: Pei Zhang, Owen E. Branson, Michael A. Freitas and Mark R. Parthun Source Type: research
Avoiding false discovery in biomarker research
Human tyrosine-protein phosphatase non-receptor type substrate 1 α (SIRPA) is a surface marker identified in cardiomyocytes differentiated from human embryonic stem cells. Our objective was to determine if circ... (Source: BMC Biochemistry)
Source: BMC Biochemistry - July 30, 2016 Category: Biochemistry Authors: Pranali Patel, Uros Kuzmanov and Seema Mital Source Type: research
Computational studies of human class V alcohol dehydrogenase - the odd sibling
All known attempts to isolate and characterize mammalian class V alcohol dehydrogenase (class V ADH), a member of the large ADH protein family, at the protein level have failed. This indicates that the class V... (Source: BMC Biochemistry)
Source: BMC Biochemistry - July 25, 2016 Category: Biochemistry Authors: Linus J. Östberg, Bengt Persson and Jan-Olov Höög Source Type: research
Effect of mutations to amino acid A301 and F361 in thermostability and catalytic activity of the β-galactosidase from Bacillus subtilis VTCC-DVN-12-01
Beta-galactosidase (EC 3.2.1.23), a commercially important enzyme, catalyses the hydrolysis of β-1,3- and β-1,4-galactosyl bonds of polymer or oligosaccharidesas well as transglycosylation of β-galactopyranosi... (Source: BMC Biochemistry)
Source: BMC Biochemistry - July 8, 2016 Category: Biochemistry Authors: Thao Thi Nguyen, Hanh Van Vu, Nhung Thi Hong Nguyen, Tuyen Thi Do and Thanh Sy Le Nguyen Source Type: research
Sustained activation of mTORC1 in macrophages increases AMPK α-dependent autophagy to maintain cellular homeostasis
The mechanistic target of rapamycin complex 1 (mTORC1) is a well-conserved serine/threonine protein kinase that controls autophagy as well as many other processes such as protein synthesis, cell growth, and me... (Source: BMC Biochemistry)
Source: BMC Biochemistry - July 7, 2016 Category: Biochemistry Authors: Hongjie Pan, Xiao-ping Zhong and Sunhee Lee Source Type: research
Sustained activation of mTORC1 in macrophages increases AMPKα-dependent autophagy to maintain cellular homeostasis
The mechanistic target of rapamycin complex 1 (mTORC1) is a well-conserved serine/threonine protein kinase that controls autophagy as well as many other processes such as protein synthesis, cell growth, and me... (Source: BMC Biochemistry)
Source: BMC Biochemistry - July 7, 2016 Category: Biochemistry Authors: Hongjie Pan, Xiao-ping Zhong and Sunhee Lee Source Type: research
Auto-thiophosphorylation activity of Src tyrosine kinase
Intermolecular autophosphorylation at Tyr416 is a conserved mechanism of activation among the members of the Src family of nonreceptor tyrosine kinases. Like several other tyrosine kinases, Src can catalyze th... (Source: BMC Biochemistry)
Source: BMC Biochemistry - July 7, 2016 Category: Biochemistry Authors: M. Zulema Cabail, Emily I. Chen, Antonius Koller and W. Todd Miller Source Type: research
