Copper chelation and interleukin-6 proinflammatory cytokine effects on expression of different proteins involved in iron metabolism in HepG2 cell line

In vertebrates, there is an intimate relationship between copper and iron homeostasis. Copper deficiency, which leads to a defect in ceruloplasmin enzymatic activity, has a strong effect on iron homeostasis re...

Source: BMC Biochemistry - January 24, 2017 Category: Biochemistry Authors: Luca Marco Di Bella, Roberto Alampi, Flavia Biundo, Giovanni Toscano and Maria Rosa Felice Source Type: research