Oral Candidiasis and Inflammatory Response: a Potential Synergic Contribution to the Onset of Type-2 Diabetes Mellitus
In this study, we explore the hypothesis that yeast colonization of the oral cavity directly influences the tendency of an individual to develop type 2 Diabetes. According to this hypothesis, oral yeast colonization may influence the pathway in which the immune response handles subsequent responses to glucose intake. The first part of this work presents data concerning oral Candida carriage in subjects with pre-diabetes, the second part explores the potential role of oral Candida infection, related to inflammatory response in promoting insulin resistance. (Source: Australasian Medical Journal - AMJ)
Source: Australasian Medical Journal - AMJ - July 3, 2017 Category: General Medicine Source Type: research
Fluconazole-Warfarin Interaction: A case report with deadly consequences
Adverse drug-drug interactions are more common in the elderly because of the commonality of polypharmacy. When one of the interacting drugs has a low therapeutic index, the consequences can be life-threatening or fatal. This case describes a fatal cerebral haemorrhage in an 80-year old male on stable doses of warfarin prescribed by his cardiologist, who was prescribed fluconazole 200mg, once daily, for 14 days by an oral and maxillofacial surgeon to treat an intraoral fungal infection. The oral surgeon was aware that the patient was on warfarin and his INR two days prior to the appointment was 2.4. While a drug interaction...
Source: Australasian Medical Journal - AMJ - July 3, 2017 Category: General Medicine Source Type: research
Healthcare meets Aesthetics: New approaches to the complex oral rehabilitations with implant-supported dental prostheses
Edentulism can lead to significant functional impairment as well as unfavourable aesthetic and psychological changes in patients. Main problems include restrictions in diet, speech impairment and loss of bone tissue in the zone where the teeth are missing. Many patients choose to retard the replacement of missing teeth for economic reasons, as they believe that overdenture prosthesis can mean poor quality or poor aesthetics. The modern dentistry has greatly improved the quality of overdenture prosthesis on dental implants. Nowadays, such rehabilitative solution is considered as a fair compromise between economic and biolog...
Source: Australasian Medical Journal - AMJ - July 3, 2017 Category: General Medicine Source Type: research
Oral rehabilitation with an implant-supported mesostructure on a microvascularized mandibular graft
This article aims to demonstrate an aesthetic and functional oral rehabilitation method, both in terms of the oral cavity and the lower face, in a young patient submitted to a left lateral hemimandibulectomy, using a mesostructure fixed onto implants. (Source: Australasian Medical Journal - AMJ)
Source: Australasian Medical Journal - AMJ - July 3, 2017 Category: General Medicine Source Type: research
Trichobezoar - A hair-raising surgical emergency
We present a case of an intellectually impaired 14-year-old girl with a gastric trichobezoar discovered during an emergency laparotomy. We will discuss the limited but salient findings on history and examination. Through a review of the literature, imaging modalities and treatment options for the early versus late stage of trichobezoar presentations will be identified. Through our case, subsequent holistic management will also be highlighted to prevent recurrence. (Source: Australasian Medical Journal - AMJ)
Source: Australasian Medical Journal - AMJ - July 3, 2017 Category: General Medicine Source Type: research
Australian general practitioners ’ current practice for chronic kidney disease (CKD) detection and management
Background Guidelines for early detection of chronic kidney disease (CKD) emphasise regular testing of kidney health in high-risk individuals. However, evidence suggests that CKD is not being adequately detected or appropriately managed in primary care. Aims Assess Australian general practitioners ’ (GP) current practice in relation to CKD detection and management. Methods This was a cross-sectional study utilising a random sample of GPs identified by interrogation of the national online telephone directory, and stratified by geographical location. Data collection occurred between Octob er 2014 and January 2015. Of 2,...
Source: Australasian Medical Journal - AMJ - July 3, 2017 Category: General Medicine Source Type: research
Hypothyroidism in a 45, X phenotypic male with a Y/18 translocation
This is the first case report of a 45, X male with autoimmune thyroid disease. Chromosome analysis revealed that all cells were 45, X without chromosome Y. The entire short arm and the centromere of Y chromosome were translocated onto the short arm of chromosome 18. Fluorescence in situ hybridization revealed that the SRY gene was present in all cells. At the age of 3 years he was diagnosed with hypothyroidism, and treatment was initiated. In the rare event of 45, X karyotype in a male, hypothyroidism should be considered so that early treatment could be initiated. (Source: Australasian Medical Journal - AMJ)
Source: Australasian Medical Journal - AMJ - July 3, 2017 Category: General Medicine Source Type: research
HeberFERON, formulation based on IFNs alpha2b and gamma for the treatment of non-melanoma skin cancer
Conclusion HeberFERON is a novel, non-surgical, effective and safe option to treat advanced, high risk or recurrent non-melanoma skin cancer. (Source: Australasian Medical Journal - AMJ)
Source: Australasian Medical Journal - AMJ - July 3, 2017 Category: General Medicine Source Type: research
Risk of in-itinere accident in primary health care professionals
Conclusion A necessity to establish road safety programs rises to control such risk factors that influence the possibility to suffer a commuting accident for the sanitary personnel. (Source: Australasian Medical Journal - AMJ)
Source: Australasian Medical Journal - AMJ - July 3, 2017 Category: General Medicine Source Type: research
Plasma rich in growth factors in dentistry
Conclusion In order to determine the most effective therapeutic value for patients, further research is required. (Source: Australasian Medical Journal - AMJ)
Source: Australasian Medical Journal - AMJ - July 3, 2017 Category: General Medicine Source Type: research
Renal transplantation: Sonography and Doppler assessment of transplanted kidneys in adult Sudanese patients
Conclusion The Doppler resistive index is significantly correlated with allograft size and had no association with echogenicity. Patients with enlarged allograft had raised resistive indi ces. The study recommended that Duplex ultrasound should be used in the initial assessment and follow-up of renal transplant. (Source: Australasian Medical Journal - AMJ)
Source: Australasian Medical Journal - AMJ - July 3, 2017 Category: General Medicine Source Type: research
Renal transplantation: Sonography and Doppler assessment of transplanted kidneys in in adult Sudanese patients
Conclusion The Doppler resistive index is significantly correlated with allograft size and had no association with echogenicity. Patients with enlarged allograft had raised resistive indi ces. The study recommended that Duplex ultrasound should be used in the initial assessment and follow-up of renal transplant. (Source: Australasian Medical Journal - AMJ)
Source: Australasian Medical Journal - AMJ - July 3, 2017 Category: General Medicine Source Type: research
Improving Chances? A design strategy to improve health and wellbeing for marginalised people
Conclusion It is possible to undertake a collaborative and informed process, which can act as a catalyst for positive change and challenge the current common processes to date. (Source: Australasian Medical Journal - AMJ)
Source: Australasian Medical Journal - AMJ - July 3, 2017 Category: General Medicine Source Type: research
Painful shoulder? Remote clinical management of a Field Guide with shoulder pain and loss of shoulder function in Antarctica
We report the case of a female Field Guide based at the British Antarctic Survey ’s Rothera Science Research Station on Adelaide Island, Antarctica who independently contacted a physiotherapist specialising in climbing related injuries (GJ) located in the UK. for a second opinion. The Field Guide was experiencing significant work difficulties due to shoulder pain and subsequen t loss of function particularly in overhead activities. The case raises important issues about the medical management of Field Guides operating in extreme environments and remote locations. (Source: Australasian Medical Journal - AMJ)
Source: Australasian Medical Journal - AMJ - July 3, 2017 Category: General Medicine Source Type: research
Pre-operative immunonutrition therapy in upper gastrointestinal cancer patients
Conclusion We found no difference in post-operative outcomes; however, the pre- and post-implementation comparison was limited by poor adherence to the protocol as a consequence of late attendance at pre-admission clinic. Of those who did attend as planned, patient acceptance was high. Future studies incorporating prospective, quantitative pre-operative immunonutrition intake are needed. (Source: Australasian Medical Journal - AMJ)
Source: Australasian Medical Journal - AMJ - July 3, 2017 Category: General Medicine Source Type: research
