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Who should be checked for hepatitis C virus infection in endemic areas?
Conclusions Male gender, increasing age, and family history of liver cancer are predictors of HCV infection in endemic areas. Males with a family history of liver cancer in their first-degree relatives should be tested for HCV infection regardless of symptoms. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - August 10, 2016 Category: Tropical Medicine Source Type: research

Zika virus is arriving at the American continent
Publication date: Available online 11 August 2016 Source:Asian Pacific Journal of Tropical Medicine Author(s): Saul Levy-Blitchtein, Juana del Valle-Mendoza Zika virus is the last arbovirosis arriving at the American continent and it is able to produce severe complications due to its neurotropism, such as microcephaly and it is also associated with Guillain-Barre syndrome. However, due to its neurotropism, it causes microcephaly and is associated with GBS. Presence of Aedes aegypti in many regions of Peru makes it easier to spread and it could be present in population, not being detected because there is a lack of rapi...
Source: Asian Pacific Journal of Tropical Medicine - August 10, 2016 Category: Tropical Medicine Source Type: research

Antidotal effects of curcumin against neurotoxic agents: an updated review
This study found that CUR may be effective in nervous system problems induced by neurotoxic agents. However, due to the lack of information on human, more investigations are needed to determine the efficacy of CUR as an antidote matter. The current study aimed to critically review the recent literature data from 2014 to 2016 that regarding the therapeutic aspects of CUR versus neurotoxic agents-induced brain damage and its involved mechanisms. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - August 9, 2016 Category: Tropical Medicine Source Type: research

Estimated number of local transmission cases of Zika virus infection imported from Brazil to France
Publication date: Available online 10 August 2016 Source:Asian Pacific Journal of Tropical Medicine Author(s): Somsri Wiwanitkit, Viroj Wiwanitkit The Zika virus infection becomes the present public health threat and the control of this disease needs international collaboration. An important problem is the international travel that promotes the importation of Zika virus disease to the new setting. The local transmission of the imported infection is the big problem. Based on the available data on published articles, in this letter, the authors estimated the number of local transmission cases, by both mosquito borne and ...
Source: Asian Pacific Journal of Tropical Medicine - August 9, 2016 Category: Tropical Medicine Source Type: research

Meteorological influences on dengue transmission in Pakistan
Conclusions This study provides preliminary results of climate influences on dengue transmission in the Lahore District of Pakistan. An increasing dengue transmission risk accompanied by frequent climate changes should be noted. Integrating the influences of climate variability into disease prevention strategies should be considered by public health authorities. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - August 9, 2016 Category: Tropical Medicine Source Type: research

Chikungunya infection: A potential re-emerging global threat
Publication date: Available online 10 August 2016 Source:Asian Pacific Journal of Tropical Medicine Author(s): Shanmugaraj Bala Murugan, Ramalingam Sathishkumar Infectious diseases are indeed a lifelong threat to everyone irrespective of age, sex, lifestyle and socio-economic status. The infectious diseases have persisted among the prominent causes of death globally. Recently, re-emergence of Chikungunya viral infection harmed many in Asian and African countries. Chikungunya was considered as a major threat in developing and under-developed countries; the recent epidemiological outbreak of Chikungunya in La Reunion urg...
Source: Asian Pacific Journal of Tropical Medicine - August 9, 2016 Category: Tropical Medicine Source Type: research

Effect and mechanism of Irbesartan on occurrence of ventricular arrhythmias in rats with myocardial ischemia through connexin43 (cx43)
Conclusions Irbesartan can inhibit the injury of H9c2 cardiomyocytes and the decreased expression of Cx43 that are induced by the ischemic myocardial infarction. Irbesartan can also improve the reconstruction of Cx43 in rats with ischemic myocardium to inhibit the myocardial infarction-induced arrhythmias. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - August 9, 2016 Category: Tropical Medicine Source Type: research

The phylogenetic and evolutionary history of Kokobera virus
Conclusions Data from the study showed as Kokobera virus, despite of its ancient origin and its circulation before the European colonization, remained limited to the Australian Country and nowadays limited mostly to the regions were Australian marsupials are mostly found. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - August 9, 2016 Category: Tropical Medicine Source Type: research

Arginine kinase in Toxocara canis: Exon-intron organization, functional analysis of site-directed mutants and evaluation of putative enzyme inhibitors
Conclusions Arginine kinase in T. canis has a seven-exon/six-intron gene structure. However, further studies are needed to identify a specific compound within the extract causing the inhibitory effect and also to determine the molecular mechanisms behind inhibition of arginine kinase in T. canis. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - August 9, 2016 Category: Tropical Medicine Source Type: research

Activation and IL-1 β secretion of human peripheral phagocytes infected with Actinomadura madurae, Nocardia asteroides and Candida albicans
Conclusions The extent of cell-viability and activation as well IL-1β secretion may be related with the virulence of C. albicans and N. asteroides and other parameters remain to be explored for assesing the virulence of A. madurae. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - August 9, 2016 Category: Tropical Medicine Source Type: research

Melaleuca quinquenervia (Cav.) S.T. Blake (Myrtales: Myrtaceae): natural alternative for mosquito control
Conclusions The adulticide activity was achieved with impregnated bottles at 40 and 50 mg/mL with the three mosquitoes species. In larvae, a growth inhibition was detected when exposed to sublethal doses. The results indicate that M. quinquinervia is a plant with promising environmentally sustainable source for vector control. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - August 9, 2016 Category: Tropical Medicine Source Type: research

Biotechnological intervention in Betelvine (Piper betle L.): a review on recent advances and future prospects
Publication date: Available online 10 August 2016 Source:Asian Pacific Journal of Tropical Medicine Author(s): Suryasnata Das, Reena Parida, I. Sriram Sandeep, Sanghamitra Nayak, Sujata Mohanty Betelvine (Piper betel L.) is cultivated for its deep green heart shaped leaf for (15-20) million Indian and 2 billion foreign consumers annually. The crop provides Rs (6 000-7 000) million of national income per year and at the same time leaves worth Rs (30-40) million is exported to other countries. The leaves are not only used directly for chewing purposes but also possesses antioxidant, anti-inflammatory, anti-apoptotic, ...
Source: Asian Pacific Journal of Tropical Medicine - August 9, 2016 Category: Tropical Medicine Source Type: research

Albiflorin Granule significantly decreased the cholesterol gallstone formation by the regulation of insulin transduction signal
Conclusions The model of insulin resistance in cholesterol gallstone guinea pig was successfully established, which plays an important role in the cholesterol gallstone formation. All aspects of insulin signaling pathway are involved in gallstone formation. Albiflorin can regulate various aspects of insulin signal transduction pathway to prevent the formation of gallbladder. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - August 4, 2016 Category: Tropical Medicine Source Type: research

The research and development on the antioxidants in prevention of diabetic complications
Publication date: Available online 5 August 2016 Source:Asian Pacific Journal of Tropical Medicine Author(s): Mohammad Rahimi-Madiseh, Afsaneh Malekpour-Tehrani, Mahmoud Bahmani, Mahmud Rafieian-kopaei Diabetes mellitus can damage the eyes, kidneys, nerves and heart. Microvascular and macrovascular disorders are the leading causes of morbidity and mortality in diabetic patients. Hyperglycemia can increase the indicators of lipid peroxidation and oxidative stress in which free radicals have the main role in the pathogenesis of these complications. Therefore, antioxidants which combat oxidative stress should be able to...
Source: Asian Pacific Journal of Tropical Medicine - August 4, 2016 Category: Tropical Medicine Source Type: research

Canova medication changes TNF- α and IL-10 serum levels in mice infected with Trypanosoma cruzi Y strain
Conclusions CM may change the balance between plasma cytokine levels (TNF-α and IL-10) in mice infected with Y strain T. cruzi, with important consequences leading towards a more severe infection. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - August 3, 2016 Category: Tropical Medicine Source Type: research