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Adipose tissue-derived stem cells ameliorates dermal fibrosis in a mouse model of scleroderma
Conclusions ADSCs may provide a feasible and practical treatment for autoimmune diseases such as LS and ameliorate dermal fibrosis. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - November 8, 2016 Category: Tropical Medicine Source Type: research

Effect of PPAR γ agonist (rosiglitazone) on the secretion of Th2 cytokine in asthma mice
Conclusions Rosiglitazone can regulate the proportion of Treg and Th17 cells and inhibit the secretion of Th2 cytokines, which inhibit the airway inflammatory response for asthma mice effectively. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - November 7, 2016 Category: Tropical Medicine Source Type: research

Evaluation of interleukin 8  +2767 A/T polymorphism in visceral leishmaniasis
Conclusions Our findings indicate that the IL-8 +2767 polymorphism is significantly involved in impaired immune responses against VL and it could be considered as a risk factor for the VL progress. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - November 6, 2016 Category: Tropical Medicine Source Type: research

In  vitro biofilm formation in ESBL producing Escherichia coli isolates from cage birds
Conclusions As a result, biofilm formation in cage bird feces originated ESBL positive Escherichia coli isolates was performed for the first time in Turkey. In order to present the relation between pathogenicity and biofilm production in animal originated ESBL positive isolates, further studies are required. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - November 6, 2016 Category: Tropical Medicine Source Type: research

Iron dysregulation in beta-thalassemia
Publication date: Available online 3 November 2016 Source:Asian Pacific Journal of Tropical Medicine Author(s): Kamonlak Leecharoenkiat, Pathrapo, Lithanatudom, Wannapa Sornjai, Duncan R. Smith Iron deficiency anemia and iron overload conditions affect more than one billion people worldwide. Iron homeostasis involves the regulation of cells that export iron into the plasma and cells that utilize or store iron. The cellular iron balance in humans is primarily mediated by the hepcidin-ferroportin axis. Ferroportin is the sole cellular iron export protein, and its expression is regulated transcriptionally, post-transcr...
Source: Asian Pacific Journal of Tropical Medicine - November 3, 2016 Category: Tropical Medicine Source Type: research

Based on the risk of dengue virus transmission via blood transfusion: What about the risk in case of Zika virus?
Publication date: Available online 3 November 2016 Source:Asian Pacific Journal of Tropical Medicine Author(s): Somsri Wiwanitkit, Viroj Wiwanitkit The risk of dengue virus transmission via blood transfusion is confirmed. As a similar virus, the risk for the case of Zika virus should be mentioned. Here, the authors calculated for the risk of Zika virus transmission via blood transmission referring to the previous data on the risk in case of dengue virus. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - November 3, 2016 Category: Tropical Medicine Source Type: research

In vitro biofilm formation in ESBL producing Escherichia coli isolates from cage birds
Conclusions As a result, biofilm formation in cage bird feces originated ESBL positive Escherichia coli isolates was performed for the first time in Turkey. In order to present the relation between pathogenicity and biofilm production in animal originated ESBL positive isolates, further studies are required. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - November 3, 2016 Category: Tropical Medicine Source Type: research

Evaluation of Interleukin 8 +2767 A/T polymorphism in visceral leishmaniasis
Conclusions Our findings indicate that the IL-8 +2767 polymorphism is significantly involved in impaired immune responses against VL and it could be considered as a risk factor for the VL progress. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - November 1, 2016 Category: Tropical Medicine Source Type: research

Corrigendum to “CETP polymorphisms confer genetic contribution to centenarians of Hainan, south of China” [Asian Pac J Trop Med 9 (9) (2016) 872–876]
Publication date: Available online 19 October 2016 Source:Asian Pacific Journal of Tropical Medicine Author(s): Yun-Xia Zhang, Ya Su, Li Tang, Ze-Xing Yang, Dai-Feng Zhou, Yi-Min Qiu (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - October 29, 2016 Category: Tropical Medicine Source Type: research

Anti-tubercular peptides: A quest of future therapeutic weapon to combat tuberculosis
Publication date: Available online 19 October 2016 Source:Asian Pacific Journal of Tropical Medicine Author(s): Ameer Khusro, Chirom Aarti, Paul Agastian Tuberculosis (TB) is a symbolic menace to mankind, infecting almost one third of the world's populace and causing over a million mortalities annually. Mycobacterium tuberculosis (Mtb) is the key pathogen of TB that invades and replicates inside the host's macrophage. With the emerging dilemma of multi-drug resistant tuberculosis (MDR-TB) and extensively-drug resistant tuberculosis (XDR-TB), the exigency for developing new TB drugs is an obligation now for worldwide r...
Source: Asian Pacific Journal of Tropical Medicine - October 29, 2016 Category: Tropical Medicine Source Type: research

Mechanism of action of Zhuyu Annao pill in mice with cerebral intrahemorrhage based on TLR4
Conclusions Zhuyu Annao pill can alleviateencephaledema for mice with ICH and reduce inflammatory responsesandnerve cell apoptosis. TLR4 can mediate inflammatory injury induced by ICH. Thus, Zhuyu Annao pill can play a protective role for brains by decreasing the expression of TLR4. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - October 29, 2016 Category: Tropical Medicine Source Type: research

Comparative genome analysis between Southeast Asian and South American Zika viruses
Conclusions These findings may help explain the cross-reactivity of DENV antibodies to ZIKV. Thus, major caveats must be exercised in using existing diagnostic tools for ZIKV. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - October 29, 2016 Category: Tropical Medicine Source Type: research

Anti-tumor activity of tanshinone IIA in combined with cyclophosphamide against Lewis mice with lung cancer
Conclusions Tan IIA in combined with CTX can down regulate Bcl-2 expression in lung cancer tissues, up regulate Bax expression, inhibit the neovascularization of tumor tissues, and enhance the immunological function, with a significant anti-tumor activity. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - October 29, 2016 Category: Tropical Medicine Source Type: research

Modifiable determinants of attitude towards dengue vaccination among healthy inhabitants of Aceh, Indonesia: Findings from a community-based survey
Conclusions This study reveals that low KAP regarding dengue fever, low education level and low socioeconomic status are associated with a poor attitude towards dengue vaccination. Therefore, inhabitants of suburbs who are working as farmers or traditional market traders with low socioeconomic status are the most appropriate target group for a dengue vaccine introduction program. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - October 29, 2016 Category: Tropical Medicine Source Type: research

Protoscolicidal and immunomodulatory activity of Ziziphora tenuior extract and its fractions
Conclusion The Z. tenuior extract and its fractions were effective against protoscolices yet the effect of total extract was considerable. Our findings indicates that the extract and its ethanolic and petroleum ether fractions could have anti-inflammatory properties. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - October 29, 2016 Category: Tropical Medicine Source Type: research