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MiR-200a and miR-200b target PTEN to regulate the endometrial cancer cell growth in vitro
Conclusion miR-200a and miR-200b can promote the endometrial cancer cell growth in vitro by targeted inhibition of PTEN gene expression. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - May 18, 2017 Category: Tropical Medicine Source Type: research

Traditional usage, phytochemistry and pharmacology of Croton sylvaticus Hochst. ex C. Krauss
Publication date: Available online 17 May 2017 Source:Asian Pacific Journal of Tropical Medicine Author(s): Alfred Maroyi Croton sylvaticus (C. sylvaticus) is widely used as herbal medicine by the indigenous people of tropical Africa. The potential of C. sylvaticus as herbal medicine, the phytochemistry and pharmacological properties of its parts used as herbal medicines are reviewed. The extensive literature survey revealed that C. sylvaticus is traditionally used to treat or manage at least 24 human and animal diseases and ailments. The species is used as herbal medicine for diseases and ailments such as abdominal pai...
Source: Asian Pacific Journal of Tropical Medicine - May 18, 2017 Category: Tropical Medicine Source Type: research

Activity of Tagetes minuta Linnaeus (Asteraceae) essential oil against L3 Anisakis larvae type 1
Conclusions The results obtained, showing a strong activity against Anisakis larvae, confirm TEO as a larvicidal agent in the treatment of human anisakidosis and in the industrial marinating process. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - May 18, 2017 Category: Tropical Medicine Source Type: research

Euphorbia neriifolia L.: Review on botany, ethnomedicinal uses, phytochemistry and biological activities
Publication date: Available online 18 May 2017 Source:Asian Pacific Journal of Tropical Medicine Author(s): Prashant Y. Mali, Shital S. Panchal The present review is intended to provide information on botany, ethnomedicinal uses, phytochemistry and biological activities of various parts of Euphorbia neriifolia (E. neriifolia). E. neriifolia has several ethnomedicinal uses. The latex of E. neriifolia is used as laxative, purgative, rubefacient, carminative and expectorant as well as in treatment of whooping cough, gonorrhea, leprosy, asthma, dyspepsia, jaundice, enlargement of the spleen, tumors, stone in the bladder, a...
Source: Asian Pacific Journal of Tropical Medicine - May 18, 2017 Category: Tropical Medicine Source Type: research

Pistacia chinensis: Strong antioxidant and potent testicular toxicity amelioration agent
Conclusions It is concluded that some bioactive antioxidants of P. chinensis bark might be a good source to isolate the potent antioxidant components. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - May 3, 2017 Category: Tropical Medicine Source Type: research

In  vitro, in vivo and in silico anti-hyperglycemic inhibition by sinigrin
Conclusions It can be evident from the present results that sinigrin has potent anti-hyperglycemic activity and it may prove to be effective treatment for the hyperglycemia. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - April 10, 2017 Category: Tropical Medicine Source Type: research

Combination of serum tumor markers dickkopf-1, DCP and AFP for the diagnosis of primary hepatocellular carcinoma
Conclusion The combination of AFP, DCP and dickkopf-1 as a biomarker panel can significantly improve the detection power with much higher sensitivity and specificity for HCC than any of the biomarkers alone. The tests are convenient and inexpensive, and may serve as a valuable addition to current options for the diagnosis of HCC. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - April 10, 2017 Category: Tropical Medicine Source Type: research

Acacia karroo Hayne: Ethnomedicinal uses, phytochemistry and pharmacology of an important medicinal plant in southern Africa
Publication date: Available online 6 April 2017 Source:Asian Pacific Journal of Tropical Medicine Author(s): Alfred Maroyi Acacia karroo (A. karroo) has been used as herbal medicine by the indigenous people of southern Africa for several centuries. The potential of A. karroo as herbal medicine, its associated phytochemistry and biological activities are reviewed. The extensive literature survey revealed that A. karroo is traditionally used to treat or manage 32 and five human and animal diseases and ailments, respectively. The species is used as herbal medicine for diseases and ailments such as colds, diarrhoea, dysente...
Source: Asian Pacific Journal of Tropical Medicine - April 10, 2017 Category: Tropical Medicine Source Type: research

Preliminary study on investigation of zoonotic visceral leishmaniasis in endemic foci of Ethiopia by detecting Leishmania infections in rodents
Conclusions Leishmania donovani might circulate among different species of rodents in kala-azar endemic lowlands and valleys of Ethiopia by Phlebotomus orientalis and Phlebotomus martini. Detailed studies to substantiate the preliminary data on the possible role of these rodents are urgently needed. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - April 10, 2017 Category: Tropical Medicine Source Type: research

Microsporidiosis in Iran: A systematic review and meta-analysis
Conclusions This study may be the first systematic review and meta-analysis that provides a broad outlook on the prevalence of microsporidiosis in Iran. It is necessary to investigate Microsporidia infection in vertebrate and invertebrate hosts and environmental resources in Iran. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - April 10, 2017 Category: Tropical Medicine Source Type: research

The protection of Thymus vulgaris leaves alcoholic extract against hepatotoxicity of alcohol in rats
Conclusion T. vulgaris extract protected hepatocytes from damaging by alcohol reflecting improvement on liver performance and inhibition of oxidative stress status of liver. T. vulgaris extract appeared hepatoprotective, hypolipidemic and antioxidant activities on alcohol-mediate hepatotoxicity rats compared to silymarin. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - April 10, 2017 Category: Tropical Medicine Source Type: research

Time-kill kinetics and biocidal effect of Euclea crispa leaf extracts against microbial membrane
Conclusion This study suggests the leaf of Euclea crispa a source of bioactive compound with membrane attack as one of the mechanisms of its biocidal action. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - April 10, 2017 Category: Tropical Medicine Source Type: research

Advances in research on Zika virus
Publication date: Available online 6 April 2017 Source:Asian Pacific Journal of Tropical Medicine Author(s): Amjad Ali, Braira Wahid, Shazia Rafique, Muhammad Idrees Zika virus (ZIKV) is rapidly spreading across the America and its devastating outcomes for pregnant women and infants have driven this previously ignored pathogen into the limelight. Clinical manifestations are fever, joint pain or rash and conjunctivitis. Emergence of ZIKV started with a first outbreak in the Pacific area in 2007, a second large outbreak occurred in the Pacific in 2013/2014 and subsequently the virus spread in other Pacific islands. Thr...
Source: Asian Pacific Journal of Tropical Medicine - April 10, 2017 Category: Tropical Medicine Source Type: research

Antitumor effect of thymoquinone combined with resveratrol on mice transplanted with breast cancer
Conclusions The combination of TQ and RES against breast cancer in mice can work synergistically. The anticancer effect of this combination is mediated by apoptosis induction, angiogenesis inhibition and immune modulation. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - April 10, 2017 Category: Tropical Medicine Source Type: research

Endogamous marriage and the prevalence of hemoglobin E in ethnic groups of northern Thailand
Conclusion Our study strongly documents that cultural impact has to be considered in the extensive prevalence studies for genetic disorders in the ethnic groups of northern Thailand. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - April 10, 2017 Category: Tropical Medicine Source Type: research