Asian Pacific Journal of Tropical Medicine This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

miR-21 targets and inhibits tumor suppressor gene PTEN to promote prostate cancer cell proliferation and invasion: An experimental study
Conclusions miR-21 can target and inhibit tumor suppressor gene PTEN expression to promote prostate cancer cell proliferation and invasion. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - November 11, 2016 Category: Tropical Medicine Source Type: research

NS1 antigen: A new beam of light in the early diagnosis of dengue infection
Conclusions NS1 antigen detection ELISA is highly suitable diagnostic tools and it also has great value for use in outbreak and epidemic situation. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - November 9, 2016 Category: Tropical Medicine Source Type: research

Asiatic acid-pectin hydrogel matrix patch transdermal delivery system influences parasitaemia suppression and inflammation reduction in P. berghei murine malaria infected Sprague-Dawley rats
Conclusions AA influences bio-physicochemical changes and parasitaemia suppression in dose dependent manner. In comparison by dose administered, AA has much better efficacy than CHQ. AA may be a useful antimalarial. AA and CHQ displays bimodal peaks suggesting possible synergism if used in combination therapy. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - November 9, 2016 Category: Tropical Medicine Source Type: research

Geohelminths eggs contamination of sandpits in Vladivostok, Russia
Conclusions Considering the high sand contamination with parasite infective elements of both human and animal origin, measures to improve environmental and sanitary conditions are indicated, as well as promoting the concept of responsible pet ownership. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - November 9, 2016 Category: Tropical Medicine Source Type: research

Control of animal brucellosis: the Malaysian experience
Publication date: Available online 9 November 2016 Source:Asian Pacific Journal of Tropical Medicine Author(s): M. Zamri-Saad, M.I. Kamarudin Brucellosis is a zoonotic disease characterized by reproductive failure in animals and undulent fever in humans. In cattle, it is caused by Brucella abortus while in goats by Brucella melitensis, the main cause of brucellosis in humans. Brucellosis in livestock has been associated with importation of animals from breeder herd of unknown disease status. The prevalence of bovine brucellosis Brucella abortus in 2014 ranged between 1%-2% in Thailand and Indonesia, and 4%-5% in Malays...
Source: Asian Pacific Journal of Tropical Medicine - November 9, 2016 Category: Tropical Medicine Source Type: research

EUS for pancreatic cystic neoplasms: The roadmap to the future is much more than just a few shades of gray
Publication date: Available online 9 November 2016 Source:Asian Pacific Journal of Tropical Medicine Author(s): Tejas Kirtane, Manoop S. Bhutani Pancreatic cystic and neoplasms are being diagnosed with increasing frequency. Accurate diagnosis and determination of benign versus malignant lesions is crucial for determining need for surveillance versus surgery or endoscopic therapy as well as avoiding unnecessary surgery in cysts with no malignant potential. Tumor markers such as KRAS and GNAS hold promise, but which molecular marker or a combination of markers is most useful and cost effective remains to be seen. Advance...
Source: Asian Pacific Journal of Tropical Medicine - November 9, 2016 Category: Tropical Medicine Source Type: research

Genetic association study of P2x7 A1513C (rs 3751143) polymorphism and susceptibility to pulmonary tuberculosis: A meta-analysis based on the findings of 11 case-control studies
Conclusions Our meta-analysis did not suggest the association of P2x7 A1513C polymorphism with PTB risk in overall or separately in Caucasian population. However, it plays a significant risk factor for predisposing PTB in Asians. Future larger sample and expression studies are needed to validate this association. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - November 9, 2016 Category: Tropical Medicine Source Type: research

Protective effects of a polymethoxy flavonoids-rich Citrus aurantium peel extract on liver fibrosis induced by bile duct ligation in mice
Conclusions CAE can efficiently regulate BDL-induced liver injury with antioxidant, anti-inflammatory, and antiapoptotic activities. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - November 9, 2016 Category: Tropical Medicine Source Type: research

Recombinant expression and purification of functional vascular endothelial growth factor-121 in the baculovirus expression system
Conclusions Results from this study demonstrated that the recombinantly-produced VEGF can be considered as a promising candidate for therapeutic purposes. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - November 9, 2016 Category: Tropical Medicine Source Type: research

Glycoproteomics analysis of plasma proteins associated with Opisthorchis viverrini infection-induced cholangiocarcinoma in hamster model
Conclusions NDRG1, FETUB and NSFL1C glycoproteins isolated by ConA-based affinity chromatography could be potential biomarkers for CCA. Plasma samples with negative for NDRG1 and FETUB proteins but positive for NSFL1C are likely to be OV-associated CCA. Nevertheless, this conclusion remains to be confirmed whether this battery test can discriminate OV-associated CCA from other risk factors. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - November 9, 2016 Category: Tropical Medicine Source Type: research

Influence of bioactive sulphated polysaccharide-protein complexes on hepatocarcinogenesis, angiogenesis and immunomodulatory activities
Conclusions The pronounced antitumor activity of sulphated polysaccharide-protein complexes of JCEM and EHEM is due to direct cytotoxic activity, anti-hepatocarcinogensis, and anti-angiogenesis. In addition, JCEM, PCEM and EHEM had an immunostimulatory response and improved the humoral immune response in HCC induced rats. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - November 9, 2016 Category: Tropical Medicine Source Type: research

Seronegative disseminated Bartonella spp. infection in an immunocompromised patient
In conclusion, Bartonella spp. infection should have a particular diagnostic consideration in immunocompromised patients with fever of unknown origin and further investigation regarding the patient’s past exposures with cats should also be elicited. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - November 9, 2016 Category: Tropical Medicine Source Type: research

Phytochemical overview and medicinal importance of Coffea species from the past until now
Publication date: Available online 9 November 2016 Source:Asian Pacific Journal of Tropical Medicine Author(s): Éva Brigitta Patay, Tímea Bencsik, Nóra Papp Coffea (coffee) species are grown in almost all countries along the Equator. Many members of the genus have a large production history and an important role both in the global market and researches. Seeds (Coffeae semen) are successfully used in food, cosmetic, and pharmaceutical industries due to its caffeine and high polyphenol content. Nowadays, the three best-known coffee species are Arabic (Coffea arabica L.), Robusta (Coffea robusta L. Linden), and Liberi...
Source: Asian Pacific Journal of Tropical Medicine - November 9, 2016 Category: Tropical Medicine Source Type: research

Medical plant extracts and natural compounds with a hepatoprotective effect against damage caused by antitubercular drugs: a review
Publication date: Available online 9 November 2016 Source:Asian Pacific Journal of Tropical Medicine Author(s): María Adelina Jiménez-Arellanes, Gabriel Alfonso Gutiérrez-Rebolledo, Mariana Meckes-Fischer, Rosalba León-Díaz Drug-induced liver injury encompasses a spectrum of diseases ranging from mild biochemical abnormalities to acute liver failure; example of this scenery is hepatotoxicity caused by the first-line antituberculous drugs isoniazid, rifampin and pyrazinamide, which are basic for treatment of drug-sensible and drug-resistant tuberculosis. In the search for pharmacological alternatives to prevent l...
Source: Asian Pacific Journal of Tropical Medicine - November 9, 2016 Category: Tropical Medicine Source Type: research

Novel neuroprotective and hepatoprorective effects of citric acid in acute malathion intoxication
Conclusions The study demonstrates a beneficial effect for citric acid upon brain oxidative stress, neuronal injury, liver and DNA damage due to acute malathion exposure. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - November 9, 2016 Category: Tropical Medicine Source Type: research